PDLIM2 (NM_021630) Human Untagged Clone

CAT#: SC321005

PDLIM2 (untagged)-Human PDZ and LIM domain 2 (mystique) (PDLIM2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PDLIM2
• Synonyms: MYSTIQUE; SLIM
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021630.4 AGAGTCGGGTAGACGGCAGCGGGAGCGGTGGCGTCTCCCCGCCTTCCCTCCCTCCCGGGC
  CTGGGCGCCCAGCCGGACAGGGGAGCGGCAGCCAGGTGAGCGCGCCCACCTGCGCCTCTC
  CGCGCGGCCCGCCCTCCCCGGCGCCGGGCTCCTCTCCGCGCCCCTGTCGGCGCGGAACCC
  TGGCCTCGTCCGCGGCCCAGCTCCCTGGAGCCTCGCATCAGCGGGGGCGCCCCCGCGAGC
  TGCGCTCTCCCCGGCCGGAGCGCTCCTCCTCCAGCCCCCAGCCCGCAGGGTACTTTGCCC
  TCGGAGCGAAGGAGGCTCCAGAACTGGTAGAGCCGGGCCATCGGGCTGGGCACCTCCCCG
  CGGCGCCCGCAGCGCGGAGTCCACTGACCGGCTCAAAGGTATGGCGTTGACGGTGGATGT
  GGCCGGGCCAGCGCCCTGGGGCTTCCGTATCACAGGGGGCAGGGATTTCCACACGCCCAT
  CATGGTGACTAAGGTGGCCGAGCGGGGCAAAGCCAAGGACGCTGACCTCCGGCCTGGAGA
  CATAATCGTGGCCATCAACGGGGAAAGCGCGGAGGGCATGCTGCATGCCGAGGCCCAGAG
  CAAGATCCGCCAGAGCCCCTCGCCCCTGCGGCTGCAGCTGGACCGGTCTCAGGCTACGTC
  TCCAGGGCAGACCAATGGGGACAGCTCCTTGGAAGTGCTGGCGACTCGCTTCCAGGGCTC
  CGTGAGGACATACACTGAGAGTCAGTCCTCCTTAAGGTCCTCCTACTCCAGCCCAACCTC
  CCTCAGCCCGAGGGCCGGCAGCCCCTTCTCACCACCACCCTCTAGCAGCTCCCTCACTGG
  AGAGGCGGCCATCAGCCGCAGCTTCCAGAGTCTGGCATGTTCCCCGGGCCTCCCCGCTGC
  TGACCGCCTGTCCTACTCAGGCCGCCCTGGAAGCCGACAGGCCGGCCTCGGCCGCGCTGG
  CGACTCGGCGGTGCTGGTGCTGCCGCCTTCCCCGGGCCCTCGTTCCTCCAGGCCCAGCAT
  GGACTCGGAAGGGGGAAGCCTCCTCCTGGACGAGGACTCGGAAGTCTTCAAGATGCTGCA
  GGAAAATCGCGAGGGACGGGCGGCCCCCCGACAGTCCAGCTCCTTTCGGCTCTTGCAGGA
  AGCCCTGGAGGCTGAGGAGAGAGGTGGCACGCCAGCCTTCTTGCCCAGCTCACTGAGCCC
  CCAGTCCTCCCTGCCCGCCTCCAGGGCCCTGGCCACCCCTCCCAAGCTCCACACTTGTGA
  GAAGTGCAGTACCAGCATCGCGAACCAGGCTGTGCGCATCCAGGAGGGCCGGTACCGCCA
  CCCCGGCTGCTACACCTGTGCCGACTGTGGGCTGAACCTGAAGATGCGCGGGCACTTCTG
  GGTGGGTGACGAGCTGTACTGTGAGAAGCATGCCCGCCAGCGCTACTCCGCACCTGCCAC
  CCTCAGCTCTCGGGCCTGAGCCCGCCATGCCCTCAGCCTGCCTCACTGCTGGGCCAGGGT
  CATGCCTATATAAGTTGGCATGGCAGGGACAATGGTGGGCAGTTGCTCTTACATGAGCTA
  AGTTTGGAGACCTGAGGCCCCTTTGTCCTCGCTGGGTGGGCCAAGGTCTGGGACCTGTCT
  TGGACTGTGGGAGACTCACCCTCACCTTGCCAGGCCTCTCCCCTGCAGGACTGGCATTGC
  ACTAGTCTGAGGTGGCCACTGCCTTTGATCAACCTTTGTGTGCCAGGGTCTAAGTAGGGT
  CGAACACAGAAGTGGGAAGGAGAGGGGTGGGCCAGGGGCTAATGGTGTCACTGTGTAAAG
  TTTTTGACATACTAGCTCTATAAATATATGAATATGGACAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021630.4 unedited
  GCGATTGTATACGACTCCTATAGGGCGGCGTGGGCCTTCGGCCATTACGGCCGGGGAGAG
  TCGGGTAGACGGCAGCGGGAGCGGTGGCGTCTCCCCGCCTTCCCTCCCTCCCGGGCCTGG
  GCGCCCAGCCGGACAGGGGAGCGGCAGCCAGGTGAGCGCGCCCACCTGCGCCTCTCCGCG
  CGGCCCGCCCTCCCCGGCGCCGGGCTCCTCTCCGCGCCCCTGTCGGCGCGGAACCCTGGC
  CTCGTCCGCGGCCCAGCTCCCTGGAGCCTCGCATCAGCGGGGGCGCCCCCGCGAGCTGCG
  CTCTCCCCGGCCGGAGCGCTCCTCCTTTTTTTTTTTTTCCCGCAGGGTACTTTGCCCTCG
  GAGCGAAGGAGGCTCCAGAACTGGTAGAGCCGGGCCATCGGGCTGGGCACCTCCCCGCGG
  CGCCCGCAGCGCGGAGTCCACTGACCGGCTCAAAGGTATGGCGTTGACGGTGGATGTGGC
  CGGGCCAGCGCCCTGGGGCTTCCGTATCACAGGGGGCAGGGATTTCCACACGCCCATCAT
  GGTGACTAAGGTGGCCGAGCGGGGCAAAGCCAAGGACGCTGACCTCCGGCCTGGAGACAT
  AATCGTGGCCATCAACGGGGAAAGCGCGGAGGGCATGCTGCATGCCGAGGCCCAGAGCAA
  GATCCGCCAGAGCCCCTCGCCCCTGCGGCTGCAGCTGGACCGGTCTCAGGCTACGTCTCC
  AGGGCAGACCAATGGGGACAGCTCCTTGGAAGTGCTGGCGACTCGCTTCCAGGGCTCCGT
  GAGGACATACACTGGAAGTCAGTACCTCCTTAGGTCTCTACTCCAGCCCAACCTCCTCAG
  CCCGAGGGACGGCAGGCGCCGTGCTGACCACCACCCCTTCTAGCAGCCTCCCTCACTTGG
  TAAAGGCCGGTCAATCAAGCCGAAGCTTCCAGAAGTCCTG
• Restriction Sites: Please inquire
• ACCN: NM_021630
• ORF Size: 1059 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_021630.4, NP_067643.2
• RefSeq Size: 1857
• RefSeq ORF: 1059
• Locus ID: 64236
• Domains: PDZ, LIM
• Gene Summary: This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
  Transcript Variant: This variant (2) differs in both UTRs and in the 5' and 3' coding regions, compared to variant 1. The resulting isoform (2) has distinct N- and C-termini and is longer than isoform 1.