AP1S2 (NM_003916) Human Untagged Clone

CAT#: SC321009

AP1S2 (untagged)-Human adaptor-related protein complex 1, sigma 2 subunit (AP1S2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AP1S2
• Synonyms: DC22; MRX59; MRXS5; MRXS21; MRXSF; PGS; SIGMA1B
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003916.3 CGGCGACAGGGGCTTCCCCTTCGCCGCCGCCGCCGCCGCCGGCCAAGCTCCGCCGCGCCC
  GCGGCCCGCGGCCGCCATGCAGTTTATGTTGCTTTTTAGTCGTCAGGGAAAGCTTCGACT
  GCAAAAATGGTATGTCCCACTATCAGACAAAGAGAAGAAAAAGATCACAAGAGAACTTGT
  TCAGACCGTTTTAGCACGGAAACCTAAAATGTGCAGCTTCCTTGAGTGGCGAGATCTGAA
  GATTGTTTACAAAAGATATGCTAGTCTGTATTTTTGCTGTGCTATTGAGGATCAGGACAA
  TGAACTAATTACCCTGGAAATAATTCATCGTTATGTGGAATTACTTGACAAGTATTTCGG
  CAGTGTCTGTGAACTAGATATCATCTTTAATTTTGAGAAGGCTTATTTTATTTTGGATGA
  GTTTCTTTTGGGAGGGGAAGTTCAGGAAACATCCAAGAAAAATGTCCTTAAAGCAATTGA
  GCAGGCTGATCTACTGCAGGAGGAAGCTGAAACCCCACGTAGTGTTCTTGAAGAAATTGG
  ACTGACATAACTCTCCTCCCTTGTTGATGACTTCTTGTGGCATTTCACACACTGTAGATG
  GTCACTCCCTTCATGTCCATGTTAGCTCATGGTGTAAGATGATGTCTTGTCAGTATTACT
  GTTTTGCTAAGCCGCTTCATTCATGCCTACACAATTTTTTTTAAAAGGGAACTTTAGTTA
  ATTAAGTGATAAGGGACTTAAATATGAATTAGAATGGTGCAGAAAGAGATACCTTTTCTG
  GATATTTTAAAGTTTAAAGGTCAGTTTCTCTTAATCTGATTATGTGCACATATGAAAATG
  GCACATCATATACATGTAAAATCAGGCAGTATACATTTATTAATTACTGTATTTGACAAA
  GGAAACTCTTAAATTATAATGTGAAACCTGGTTTTATGAAACCAAAGACTAGTGCAGCAT
  TTCAGCATATGTAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003916.3 unedited
  TCGATTGTATACGACTCCTATAGGGCGGCCGGCAAATTCGGCACGAGGCGGCGACAGGGG
  CTTCCCCTTCGCCGCCGCCGCCGCCGCCGGCCAAGCTCCGCCGCGCCCGCGGCCCGCGGC
  CGCCATGCAGTTTATGTTGCTTTTTAGTCGTCAGGGAAAGCTTCGACTGCAAAAATGGTA
  TGTCCCACTATCAGACAAAGAGAAGAAAAAGATCACAAGAGAACTTGTTCAGACCGTTTT
  AGCACGGAAACCTAAAATGTGCAGCTTCCTTGAGTGGCGAGATCTGAAGATTGTTTACAA
  AAGATATGCTAGTCTGTATTTTTGCTGTGCTATTGTGGATCAGGACAATGAACTAATTAC
  CCTGGAAATAATTCATCGTTATGTGGAATTACTTGACAAGTATTTCGGCAGTGTCTGTGA
  ACTAGATATCATCTTTAATTTTGAGAAGGCTTATTTTATTTTGGATGAGTTTCTTTTGGG
  AGGGGAAGTTCAGGAAACATCCAAGAAAAATGTCCTTAAAGCAATTGAGCAGGCTGATCT
  ACTGCAGGAGGAAGCTGAAACCCCACGTAGTGTTCTTGAAGAAATTGGACTGACATAACT
  CTCCTCCCTTGTTGATGACTTCTTGTGGCATTTCACACACTGTAGATGGTCACTCCCTTC
  ATGTCCATGTTAGCTCATGGTGTAAGATGATGTCTTGTCAGTATTACTGTTTTGCTAAGC
  CGCTTCATTCATGCCTACACAATTTTTTTTAAAAGGGAACTTTAGTTAATTAAGTGATAA
  GGACTTAAATATGAATTAGATGGTGCAGAAAGAAGATACCTTTCTGATATTTTAAAGTTT
  AAAGGTCAGTTTCTCTTAATCTGATTATGTGCACATATGAAAATGGCACATCATATACAT
  GTAAATCAGGCAGTATACATTTATATTACTGTATTTGACAAGAACTCCTTAAATTATATA
  TTGGTGAACCCTGGAGTG
• Restriction Sites: Please inquire
• ACCN: NM_003916
• ORF Size: 474 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_003916.3, NP_003907.3
• RefSeq Size: 2283
• RefSeq ORF: 474
• Locus ID: 8905
• Domains: Clat_adaptor_s
• Protein Families: Druggable Genome
• Protein Pathways: Lysosome
• Gene Summary: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]
  Transcript Variant: This variant (2) lacks an alternate in-frame 3' exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.