G3BP (G3BP1) (NM_005754) Human Untagged Clone

CAT#: SC321062

G3BP1 (untagged)-Human GTPase activating protein (SH3 domain) binding protein 1 (G3BP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: G3BP1
• Synonyms: G3BP; HDH-VIII
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005754.2 GTGTGCGGACGCAGTTGCGTGAGGGGTTTGTGCTATCCTCGGTGCTGTGGTGCAGAGCTA
  GTTCCTCTCCAGCTCAGCCGCGTAGGTTTGGACATATTTGACTCTTTTCCCCCCAGGTTG
  AATTGACCAAAGCAATGGTGATGGAGAAGCCTAGTCCCCTGCTGGTCGGGCGGGAATTTG
  TGAGACAGTATTACACACTGCTGAACCAGGCCCCAGACATGCTGCATAGATTTTATGGAA
  AGAACTCTTCTTATGTCCATGGGGGATTGGATTCAAATGGAAAGCCAGCAGATGCAGTCT
  ACGGACAGAAAGAAATCCACAGGAAAGTGATGTCACAAAACTTCACCAACTGCCACACCA
  AGATTCGCCATGTTGATGCTCATGCCACGCTAAATGATGGTGTGGTAGTCCAGGTGATGG
  GGCTTCTCTCTAACAACAACCAGGCTTTGAGGAGATTCATGCAAACGTTTGTCCTTGCTC
  CTGAGGGGTCTGTTGCAAATAAATTCTATGTTCACAATGATATCTTCAGATACCAAGATG
  AGGTCTTTGGTGGGTTTGTCACTGAGCCTCAGGAGGAGTCTGAAGAAGAAGTAGAGGAAC
  CTGAAGAAAGACAGCAAACACCTGAGGTGGTACCTGATGATTCTGGAACTTTCTATGATC
  AGGCAGTTGTCAGTAATGACATGGAAGAACATTTAGAGGAGCCTGTTGCTGAACCAGAGC
  CTGATCCTGAACCAGAACCAGAACAAGAACCTGTATCTGAAATCCAAGAGGAAAAGCCTG
  AGCCAGTATTAGAAGAAACTGCCCCTGAGGATGCTCAGAAGAGTTCTTCTCCAGCACCTG
  CAGACATAGCTCAGACAGTACAGGAAGACTTGAGGACATTTTCTTGGGCATCTGTGACCA
  GTAAGAATCTTCCACCCAGTGGAGCTGTTCCAGTTACTGGGATACCACCTCATGTTGTTA
  AAGTACCAGCTTCACAGCCCCGTCCAGAGTCTAAGCCTGAATCTCAGATTCCACCACAAA
  GACCTCAGCGGGATCAAAGAGTGCGAGAACAACGAATAAATATTCCTCCCCAAAGGGGAC
  CCAGACCAATCCGTGAGGCTGGTGAGCAAGGTGACATTGAACCCCGAAGAATGGTGAGAC
  ACCCTGACAGTCACCAACTCTTCATTGGCAACCTGCCTCATGAAGTGGACAAATCAGAGC
  TTAAAGATTTCTTTCAAAGTTATGGAAACGTGGTGGAGTTGCGCATTAACAGTGGTGGGA
  AATTACCCAATTTTGGTTTTGTTGTGTTTGATGATTCTGAGCCTGTTCAGAAAGTCCTTA
  GCAACAGGCCCATCATGTTCAGAGGTGAGGTCCGTCTGAATGTCGAAGAGAAGAAGACTC
  GAGCTGCCAGGGAAGGCGACCGACGAGATAATCGCCTTCGGGGACCTGGAGGCCCTCGAG
  GTGGGCTGGGTGGTGGAATGAGAGGCCCTCCCCGTGGAGGCATGGTGCAGAAACCAGGAT
  TTGGAGTGGGAAGGGGGCTTGCGCCACGGCAGTGAATCTTCATGGATCTTCATGCAGCCA
  TACAAACCCTGGTTCCAACAGAATGGTGAATTTTCGACAGCCTTTGGTATCTTGGAGTAT
  GACCCCAGTCTGTTATAAACTGCTTAAGTTTGTATAATTTTACTTTTTTTGTGTGTTAAT
  GGTGTGTGCTCCCTCTCCCTCTCTTCCCTTTCCTGACCTTTAGTCTTTCACTTCCAATTT
  TGTGGAATGATATTTTAGGAATAACGGACTTTTAAAGAAGCAAAAAAAAAAGACTGAATT
  TCCTTGCTTACTTTGCATATACAGACTGGATTTTTTTTTTTTTTTTACAGCCATTTCCCC
  AAAGGAATGTCTTGCATATTACTGACATTTGGTATGTTTCATTCATTGGAATATTTCTTA
  TTTTCTACGTGTTTGAAAAGCCTGTAAGAAATACAGGATTTGATAATATTTTGAAGGCAG
  GAAAAACCCAAATTGTTTCTTCTTTGAGAGTCATGACTACCTTCTGGTGTGGAGAAATTG
  CCATTGGAAAATTTGACAATTTTGATTCTCACTGGTATGTTTAAAAACTGAATAAAAGGA
  ATAGAATTTTTTTTTGATAAAGGATCACAAAACAATTCTAAAACCTAACTGTTTTTACCA
  TTGAAATTTAAATTGTGATAATAGGTTTTAAATGTCTAGAATGCAACTGATAGGCTTTTC
  TTGAACTGTTAGTTTTTTTGAAGTAGTTTTTTCATGTTTAATTTGTATTTGTAAAAAAAC
  AAAAAGCAAAAAAATTCCCAAAACCCAGATAACAACCAGAGCAAAACTGTTGTGCCTTCT
  ATTTATCTTTGATTTCAGTCTTGGCAATTGTTTAAAAAAAAAATCTAGATTTGTTTTATT
  AGGTTCAGAGTATGTGGGGAATTATAGAATCCCTCTTTCATCACTTTGTGTATGTCTTTT
  GTTAACATATTTGTTATGCCTTATTCTAAAATTGAGTCTCAAACTGGAATGCCTTTGAAG
  ACAGATGCTTCTATAGAGGTTCTTTGACCTAAATAGTTCAGCATTTGTATTTTTATTCTG
  GTATCTAATCAGATTCCTAATCATAGCCCGTAAGAAGGAATGTTACTTTAATATTGGACT
  TTGCTCATGTGCTCGTGTCCGCATTTTTTTTTTTCTTAAAATCATAGCCATATGGTAAAT
  TTTCTATTTTGTTATGGTTCTCTTTTATTGATGGGCATGCAGTGGGTGTTACTTGGAAAT
  GGCCAATTTTTATTAAAATATTTCTGGAAGAAAATCCAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005754.2 unedited
  TACCATTGTATACGACTCCTATAGGGCGGCCGCGAATTCGGCCATTACGGCCGGGGGTGT
  GCGGACGCAGTTGCGTGAGGGGTTTGTGCTATCCTCGGTGCTGTGGTGCAGAGCTAGTTC
  CTCTCCAGCTCAGCCGCGTAGGTTTGGACATATTTGACTCTTTTCCCCCCAGGTTGAATT
  GACCAAAGCAATGGTGATGGAGAAGCCTAGTCCCCTGCTGGTCGGGCGGGAATTTGTGAG
  ACAGTATTACACACTGCTGAACCAGGCCCCAGACATGCTGCATAGATTTTATGGAAAGAA
  CTCTTCTTATGTCCATGGGGGATTGGATTCAAATGGAAAGCCAGCAGATGCAGTCTACGG
  ACAGAAAGAAATCCACAGGAAAGTGATGTCACAAAACTTCACCAACTGCCACACCAAGAT
  TCGCCATGTTGATGCTCATGCCACGCTAAATGATGGTGTGGTAGTCCAGGTGATGGGGCT
  TCTCTCTAACAACAACCAGGCTTTGAGGAGATTCATGCAAACGTTTGTCCTTGCTCCTGA
  GGGGTCTGTTGCAAATAAATTCTATGTTCACAATGATATCTTCAGATACCAAGATGAGGT
  CTTTGGTGGGTTTGTCACTGAGCCTCAGGAGGAGTCTGAAGAAGAAGTAGAGGAACCTGA
  AGAAAGACAGCAAACACCTGAGTGGTACCTGATGATTCTGGAACTTTCTATGATCAGGCA
  GTTGTCAGTAATGACATGGAAGAACATTTAGAGGAGCCTGTTGCTGAACCAGAGCCTGAT
  CCTGACCAGACCCAGACAGACCCTGTATCTGAAATCCAGAGGAAAGCCTGAGCCAGTATT
  AGAGAACTGCCCTGAGATGCTCAGAGAGTTCTTCTCAGCACTGCAGAACATAGCTCAGAC
  GGTACAGAGACTGAGAACTTTTTCTTGGCATCTGGTGACCAGTAAGAAATCCTCAACCAA
  TGGGAGCTGT
• Restriction Sites: Please inquire
• ACCN: NM_005754
• ORF Size: 1401 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005754.2, NP_005745.1
• RefSeq Size: 2855
• RefSeq ORF: 1401
• Locus ID: 10146
• Domains: RRM, NTF2
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 2. Variants 1 and 2 encode the same isoform.