DARC (ACKR1) (NM_002036) Human Untagged Clone

CAT#: SC321096

DARC (untagged)-Human Duffy blood group, chemokine receptor (DARC), transcript variant 2


  "NM_002036" in other vectors (7)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ACKR1
Synonyms CCBP1; CD234; DARC; DARC/ACKR1; Dfy; FY; GPD; GpFy; WBCQ1
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_002036.2 GCAGGCAGTGGGCGTGGGGTAAGGCTTCCTGATGCCCCCTGTCCCTGCCCAGAACCTGAT
GGCCCTCATTAGTCCTTGGCTCTTATCTTGGAAGCACAGGCGCTGACAGCCGTCCCAGCC
CTTCTGTCTGCGGGCCTGAACCAAACGGTGCCATGGGGAACTGTCTGCACAGGGCGGAGC
TCTCCCCCTCAACTGAGAACTCAAGTCAGCTGGACTTCGAAGATGTATGGAATTCTTCCT
ATGGTGTGAATGATTCCTTCCCAGATGGAGACTATGGTGCCAACCTGGAAGCAGCTGCCC
CCTGCCACTCCTGTAACCTGCTGGATGACTCTGCACTGCCCTTCTTCATCCTCACCAGTG
TCCTGGGTATCCTAGCTAGCAGCACTGTCCTCTTCATGCTTTTCAGACCTCTCTTCCGCT
GGCAGCTCTGCCCTGGCTGGCCTGTCCTGGCACAGCTGGCTGTGGGCAGTGCCCTCTTCA
GCATTGTGGTGCCCGTCTTGGCCCCAGGGCTAGGTAGCACTCGCAGCTCTGCCCTGTGTA
GCCTGGGCTACTGTGTCTGGTATGGCTCAGCCTTTGCCCAGGCTTTGCTGCTAGGGTGCC
ATGCCTCCCTGGGCCACAGACTGGGTGCAGGCCAGGTCCCAGGCCTCACCCTGGGGCTCA
CTGTGGGAATTTGGGGAGTGGCTGCCCTACTGACACTGCCTGTCACCCTGGCCAGTGGTG
CTTCTGGTGGACTCTGCACCCTGATATACAGCACGGAGCTGAAGGCTTTGCAGGCCACAC
ACACTGTAGCCTGTCTTGCCATCTTTGTCTTGTTGCCATTGGGTTTGTTTGGAGCCAAGG
GGCTGAAGAAGGCATTGGGTATGGGGCCAGGCCCCTGGATGAACATCCTGTGGGCCTGGT
TTATTTTCTGGTGGCCTCATGGGGTGGTTCTAGGACTGGATTTCCTGGTGAGGTCCAAGC
TGTTGCTGTTGTCAACATGTCTGGCCCAGCAGGCTCTGGACCTGCTGCTGAACCTGGCAG
AAGCCCTGGCAATTTTGCACTGTGTGGCTACGCCCCTGCTCCTCGCCCTATTCTGCCACC
AGGCCACCCGCACCCTCTTGCCCTCTCTGCCCCTCCCTGAAGGATGGTTTTCTCATCTGG
ACACCCTTGGAAGCAAATCCTAGTTCTCTTCCCACCTGTCAACCTGAATTAAAGTCTACA
CTGCCTTTGTGATAAAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_002036
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002036.2, NP_002027.2
RefSeq Size 1317 bp
RefSeq ORF 1011 bp
Locus ID 2532
Cytogenetics 1q23.2
Protein Families Druggable Genome, GPCR, Transmembrane
Gene Summary 'The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus compared to isoform a.

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