TIMP3 (NM_000362) Human Untagged Clone

CAT#: SC321254

TIMP3 (untagged)-Human TIMP metallopeptidase inhibitor 3 (TIMP3)


  "NM_000362" in other vectors (6)

Reconstitution Protocol

USD 420.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol TIMP3
Synonyms HSMRK222; K222; K222TA2; SFD
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_000362.4 GCTCCTCCAGCTCCTGCTCCTTCGCCGGGAGGCCGCCCGCCGAGTCCTGCGCCAGCGCCG
AGGCAGCCTCGCTGCGCCCCATCCCGTCCCGCCGGGCACTCGGAGGGCAGCGCGCCGGAG
GCCAAGGTTGCCCCGCACGGCCCGGCGGGCGAGCGAGCTCGGGCTGCAGCAGCCCCGCCG
GCGGCGCGCACGGCAACTTTGGAGAGGCGAGCAGCAGCCCCGGCAGCGGCGGCAGCAGCG
GCAATGACCCCTTGGCTCGGGCTCATCGTGCTCCTGGGCAGCTGGAGCCTGGGGGACTGG
GGCGCCGAGGCGTGCACATGCTCGCCCAGCCACCCCCAGGACGCCTTCTGCAACTCCGAC
ATCGTGATCCGGGCCAAGGTGGTGGGGAAGAAGCTGGTAAAGGAGGGGCCCTTCGGCACG
CTGGTCTACACCATCAAGCAGATGAAGATGTACCGAGGCTTCACCAAGATGCCCCATGTG
CAGTACATCCATACGGAAGCTTCCGAGAGTCTCTGTGGCCTTAAGCTGGAGGTCAACAAG
TACCAGTACCTGCTGACAGGTCGCGTCTATGATGGCAAGATGTACACGGGGCTGTGCAAC
TTCGTGGAGAGGTGGGACCAGCTCACCCTCTCCCAGCGCAAGGGGCTGAACTATCGGTAT
CACCTGGGTTGTAACTGCAAGATCAAGTCCTGCTACTACCTGCCTTGCTTTGTGACTTCC
AAGAACGAGTGTCTCTGGACCGACATGCTCTCCAATTTCGGTTACCCTGGCTACCAGTCC
AAACACTACGCCTGCATCCGGCAGAAGGGCGGCTACTGCAGCTGGTACCGAGGATGGGCC
CCCCCGGATAAAAGCATCATCAATGCCACAGACCCCTGAGCGCCAGACCCTGCCCCACCT
CACTTCCCTCCCTTCCCGCTGAGCTTCCCTTGGACACTAACTCTTCCCAGATGATGACAA
TGAAATTAGTGCCTGTTTTCTTGCAAATTTAGCACTTGGAACATTTAAAGAAAGGTCTAT
GCTGTCATATGGGGTTTATTGGGAACTATCCTCCTGGCCCCACCCTGCCCCTTCTTTTTG
GTTTTGACATCATTCATTTCCACCTGGGAATTTCTGGTGCCATGCCAGAAAGAATGAGGA
ACCTGTATTCCTCTTCTTCGTGATAATATAATCTCTATTTTTTTAGGAAAACAAAAATGA
AAAACTACTCCATTTGAGGATTGTAATTCCCACCCCTCTTGCTTCTTCCCCACCTCACCA
TCTCCCAGACCCTCTTCCCTTTGCCCTTCTCCTCCAATACATAAAGGACACAGACAAGGA
ACTTGCTGAAAGGCCAACCATTTCAGGATCAGTCAAAGGCAGCAAGCAGATAGACTCAAG
GTGTGTGAAAGATGTTATACACCAGGAGCTGCCACTGCATGTCCCAACCAGACTGTGTCT
GTCTGTGTCTGCATGTAAGAGTGAGGGAGGGAAGGAAGGAACTACAAGAGAGTCGGAGAT
GATGCAGCACACACACAATTCCCCAGCCCAGTGATGCTTGTGTTGACCAGATGTTCCTGA
GTCTGGAGCAAGCACCCAGGCCAGAATAACAGAGCTTTCTTAGTTGGTGAAGACTTAAAC
ATCTGCCTGAGGTCAGGAGGCAATTTGCCTGCCTTGTACAAAAGCTCAGGTGAAAGACTG
AGATGAATGTCTTTCCTCTCCCTGCCTCCCACCAGACTTCCTCCTGGAAAACGCTTTGGT
AGATTTGGCCAGGAGCTTTCTTTTATGTAAATTGGATAAATACACACACCATACACTATC
CACAGATATAGCCAAGTAGATTTGGGTAGAGGATACTATTTCCAGAATAGTGTTTAGCTC
ACCTAGGGGGATATGTTTGTATACACATTTGCATATACCCACATGGGGACATAAGCTAAT
TTTTTTACAGGACACAGAATTCTGTTCAATGCTGTTAAATATGCCAATAGTTTAATCTCT
TCTATTTTGTTGTCGTTGCTTGTTTGAAGAAAATCATGACATTCCAAGTTGACATTTTTT
TTTCATTTTAATTAAAATTTGAAATTCTGAACACCGTCAGCACCCTCTCTTCCCTATCAT
GGGTCATCTGACCCCTGTCCGTCTCCTTGTCCCTGCTTCATGTTTGGGGGCCTTTCTTTA
ACTGCCTTCCTGGCTTAGCTCAGATGGCAGATGAGAGTGTAGTCAAGGGCCTGGGCACAG
GAGGGAGAGCTGCAGAGTGTCCTGCCTGCCTTGGCTGGAGGGACACCTCTCCTGGGTGTG
GAGACAGCTTGGTTCCCTTTCCCTAGCTCCCTGGTGGGTGAATGCCACCTCCTGAGATCC
TCACCTCTTGGAATTAAAATTGTTGGTCACTGGGGAAAGCCTGAGTTTGCAACCAGTTGT
AGGGTTTCTGTTGTGTTTTTTTTTTTTTTTTTGAAATAAAACTATAATATAAATTCTCCT
ATTAAATAAAATTATTTTAAGTTTTAGTGTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_000362
Insert Size 2500 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000362.4, NP_000353.1
RefSeq Size 5496 bp
RefSeq ORF 636 bp
Locus ID 7078
Cytogenetics 22q12.3
Domains NTR
Protein Families Druggable Genome, Secreted Protein
Gene Summary 'This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.