CX3CL1 (NM_002996) Human Untagged Clone

CAT#: SC321351

CX3CL1 (untagged)-Human chemokine (C-X3-C motif) ligand 1 (CX3CL1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CX3CL1
• Synonyms: ABCD-3; C3Xkine; CXC3; CXC3C; fractalkine; neurotactin; NTN; NTT; SCYD1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002996.3 CTGAGCTCTGCCGCCTGGCTCTAGCCGCCTGCCTGGCCCCCGCCGGGACTCTTGCCCACC
  CTCAGCCATGGCTCCGATATCTCTGTCGTGGCTGCTCCGCTTGGCCACCTTCTGCCATCT
  GACTGTCCTGCTGGCTGGACAGCACCACGGTGTGACGAAATGCAACATCACGTGCAGCAA
  GATGACATCAAAGATACCTGTAGCTTTGCTCATCCACTATCAACAGAACCAGGCATCATG
  CGGCAAACGCGCAATCATCTTGGAGACGAGACAGCACAGGCTGTTCTGTGCCGACCCGAA
  GGAGCAATGGGTCAAGGACGCGATGCAGCATCTGGACCGCCAGGCTGCTGCCCTAACTCG
  AAATGGCGGCACCTTCGAGAAGCAGATCGGCGAGGTGAAGCCCAGGACCACCCCTGCCGC
  CGGGGGAATGGACGAGTCTGTGGTCCTGGAGCCCGAAGCCACAGGCGAAAGCAGTAGCCT
  GGAGCCGACTCCTTCTTCCCAGGAAGCACAGAGGGCCCTGGGGACCTCCCCAGAGCTGCC
  GACGGGCGTGACTGGTTCCTCAGGGACCAGGCTCCCCCCGACGCCAAAGGCTCAGGATGG
  AGGGCCTGTGGGCACGGAGCTTTTCCGAGTGCCTCCCGTCTCCACTGCCGCCACGTGGCA
  GAGTTCTGCTCCCCACCAACCTGGGCCCAGCCTCTGGGCTGAGGCAAAGACCTCTGAGGC
  CCCGTCCACCCAGGACCCCTCCACCCAGGCCTCCACTGCGTCCTCCCCAGCCCCAGAGGA
  GAATGCTCCGTCTGAAGGCCAGCGTGTGTGGGGTCAGGGACAGAGCCCCAGGCCAGAGAA
  CTCTCTGGAGCGGGAGGAGATGGGTCCCGTGCCAGCGCACACGGATGCCTTCCAGGACTG
  GGGGCCTGGCAGCATGGCCCACGTCTCTGTGGTCCCTGTCTCCTCAGAAGGGACCCCCAG
  CAGGGAGCCAGTGGCTTCAGGCAGCTGGACCCCTAAGGCTGAGGAACCCATCCATGCCAC
  CATGGACCCCCAGAGGCTGGGCGTCCTTATCACTCCTGTCCCTGACGCCCAGGCTGCCAC
  CCGGAGGCAGGCGGTGGGGCTGCTGGCCTTCCTTGGCCTCCTCTTCTGCCTGGGGGTGGC
  CATGTTCACCTACCAGAGCCTCCAGGGCTGCCCTCGAAAGATGGCAGGAGAGATGGCGGA
  GGGCCTTCGCTACATCCCCCGGAGCTGTGGTAGTAATTCATATGTCCTGGTGCCCGTGTG
  AACTCCTCTGGCCTGTGTCTAGTTGTTTGATTCAGACAGCTGCCTGGGATCCCTCATCCT
  CATACCCACCCCCACCCAAGGGCCTGGCCTGAGCTGGGATGATTGGAGGGGGGAGGTGGG
  ATCCTCCAGGTGCACAAGCTCCAAGCTCCCAGGCATTCCCCAGGAGGCCAGCCTTGACCA
  TTCTCCACCTTCCAGGGACAGAGGGGGTGGCCTCCCAACTCACCCCAGCCCCAAAACTCT
  CCTCTGCTGCTGGCTGGTTAGAGGTTCCCTTTGACGCCATCCCAGCCCCAATGAACAATT
  ATTTATTAAATGCCCAGCCCCTTCTGACCCATGCTGCCCTGTGAGTACTACAGTCCTCCC
  ATCTCACACATGAGCATCAGGCCAGGCCCTCTGCCCACTCCCTGCAACCTGATTGTGTCT
  CTTGGTCCTGCTGCAGTTGCCAGTCACCCCGGCCACCTGCGGTGCTATCTCCCCCAGCCC
  CATCCTCTGTACAGAGCCCACGCCCCCACTGGTGACATGTCTTTTCTTGCATGAGGCTAG
  TGTGGTGTTTCCTGGCACTGCTTCCAGTGAGGCTCTGCCCTTGGTTAGGCATTGTGGGAA
  GGGGAGATAAGGGTATCTGGTGACTTTCCTCTTTGGTCTACACTGTGCTGAGTCTGAAGG
  CTGGGTTCTGATCCTAGTTCCACCATCAAGCCACCAACATACTCCCATCTGTGAAAGGAA
  AGAGGGAGGTAAGGAATACCTGTCCCCCTGACAACACTCATTGACCTGAGGCCCTTCTCT
  CCAGCCCCTGGATGCAGCCTCACAGTCCTTACCAGCAGAGCACCTTAGACAGTCCCTGCC
  AATGGACTAACTTGTCTTTGGACCCTGAGGCCCAGAGGGCCTGCAAGGGAGTGAGTTGAT
  AGCACAGACCCTGCCCTGTGGGCCCCCAAATGGAAATGGGCAGAGCAGAGACCATCCCTG
  AAGGCCCCGCCCAGGCTTAGTCACTGAGACAGCCCGGGCTCTGCCTCCCATCACCCGCTA
  AGAGGGAGGGAGGGCTCCAGACACATGTCCAAGAAGCCCAGGAAAGGCTCCAGGAGCAGC
  CACATTCCTGATGCTTCTTCAGAGACTCCTGCAGGCAGCCAGGCCACAAGACCCTTGTGG
  TCCCACCCCACACACGCCAGATTCTTTCCTGAGGCTGGGCTCCCTTCCCACCTCTCTCAC
  TCCTTGAAAACACTGTTCTCTGCCCTCCAAGACCTTCTCCTTCACCTTTGTCCCCACCGC
  AGACAGGACCAGGGATTTCCATGATGTTTTCCATGAGTCCCCTGTTTGTTTCTGAAAGGG
  ACGCTACCCGGGAAGGGGGCTGGGACATGGGAAAGGGGAAGTTGTAGGCATAAAGTCAGG
  GGTTCCCTTTTTTGGCTGCTGAAGGCTCGAGCATGCCTGGATGGGGCTGCACCGGCTGGC
  CTGGCCCCTCAGGGTCCCTGGTGGCAGCTCACCTCTCCCTTGGATTGTCCCCGACCCTTG
  CCGTCTACCTGAGGGGCCTCTTATGGGCTGGGTTCTACCCAGGTGCTAGGAACACTCCTT
  CACAGATGGGTGCTTGGAGGAAGGAAACCCAGCTCTGGTCCATAGAGAGCAAGACGCTGT
  GCTGCCCTGCCCACCTGGCCTCTGCACTCCCCTGCTGGGTGTGGCGCAGCATATTCAGGA
  AGCTCAGGGCCTGGCTCAGGTGGGGTCACTCTGGCAGCTCAGAGAGGGTGGGAGTGGGTC
  CAATGCACTTTGTTCTGGCTCTTCCAGGCTGGGAGAGCCTTTCAGGGGTGGGACACCCTG
  TGATGGGGCCCTGCCTCCTTTGTGAGGAAGCCGCTGGGGCCAGTTGGTCCCCCTTCCATG
  GACTTTGTTAGTTTCTCCAAGCAGGACATGGACAAGGATGATCTAGGAAGACTTTGGAAA
  GAGTAGGAAGACTTTGGAAAGACTTTTCCAACCCTCATCACCAACGTCTGTGCCATTTTG
  TATTTTACTAATAAAATTTAAAAGTCTTGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAA
• Restriction Sites: Please inquire
• ACCN: NM_002996
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002996.3, NP_002987.1
• RefSeq Size: 3304 bp
• RefSeq ORF: 1194 bp
• Locus ID: 6376
• Cytogenetics: 16q21
• Domains: IL8
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Gene Summary: 'This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017]'
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).