AGPAT2 (NM_006412) Human Untagged Clone

CAT#: SC321376

AGPAT2 (untagged)-Human 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (AGPAT2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AGPAT2
• Synonyms: 1-AGPAT2; BSCL; BSCL1; LPAAB; LPAAT-beta
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006412.3 GGAGCGGGAGCGAGCTGGCGGCGCCGTCGGGCGCCGGGCCGGGCCATGGAGCTGTGGCCG
  TGTCTGGCCGCGGCGCTGCTGTTGCTGCTGCTGCTGGTGCAGCTGAGCCGCGCGGCCGAG
  TTCTACGCCAAGGTCGCCCTGTACTGCGCGCTGTGCTTCACGGTGTCCGCCGTGGCCTCG
  CTCGTCTGCCTGCTGCGCCACGGCGGCCGGACGGTGGAGAACATGAGCATCATCGGCTGG
  TTCGTGCGAAGCTTCAAGTACTTTTACGGGCTCCGCTTCGAGGTGCGGGACCCGCGCAGG
  CTGCAGGAGGCCCGTCCCTGTGTCATCGTCTCCAACCACCAGAGCATCCTGGACATGATG
  GGCCTCATGGAGGTCCTTCCGGAGCGCTGCGTGCAGATCGCCAAGCGGGAGCTGCTCTTC
  CTGGGGCCCGTGGGCCTCATCATGTACCTCGGGGGCGTCTTCTTCATCAACCGGCAGCGC
  TCTAGCACTGCCATGACAGTGATGGCCGACCTGGGCGAGCGCATGGTCAGGGAGAACCTC
  AAAGTGTGGATCTATCCCGAGGGTACTCGCAACGACAATGGGGACCTGCTGCCTTTTAAG
  AAGGGCGCCTTCTACCTGGCAGTCCAGGCACAGGTGCCCATCTTCCCCGTGGTGTACTCT
  TCCTTCTCCTCCTTCTACAACACCAAGAAGAAGTTCTTCACTTCAGGAACAGTCACAGTG
  CAGGTGCTGGAAGCCATCCCCACCAGCGGCCTCACTGCGGCGGACGTCCCTGCGCTCGTG
  GACACCTGCCACCGGGCCATGAGGACCACCTTCCTCCACATCTCCAAGACCCCCCAGGAG
  AACGGGGCCACTGCGGGGTCTGGCGTGCAGCCGGCCCAGTAGCCCAGACCACGGCAGGGC
  ATGACCTGGGGAGGGCAGGTGGAAGCCGATGGCTGGAGGATGGGCAGAGGGGACTCCTCC
  CGGCTTCCAAATACCACTCTGTCCGGCTCCCCCAGCTCTCACTCAGCCCGGGAAGCAGGA
  AGCCCCTTCTGTCACTGGTCTCAGACACAGGCCCCTGGTGTCCCCTGCAGGGGGCTCAGC
  TGGACCCTCCCCGGGCTCGAGGGCAGGGACTCGCGCCCACGGCACCTCTGGGAGCTGGGA
  TGATAAAGATGAGGCTTGCGGCTGTGGCCCGCTGGTGGGCTGAGCCACAAGGCCCCCGAT
  GGCCCAGGAGCAGATGGGAGGACCCCGAGGCCAGACGCACACTGTCCGAGCCCTCTGCTC
  AGCCGCCTGGGACCCACCAGGGTGCAGCTGGGCTCCAGGGTCCAGCCCACAAGCTGCATC
  AGGGTCTCTGGGAGAGGAGGGGCCTGGAGGGCCAGGAGTCCCAGACTCACGCACCCTGGG
  CCACAGGGAGCCGGGAATCGGGGCCTGCTGCTCCTGCTGGCCTGGAAGACTCTGTGGGGT
  CAGCACTGTACTCCGTTGCTGTTTTTTTATAAACACACTCTTGGAAGTGGCAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006412.3 unedited
  CACCTTGTATACGACTCCTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAG
  GAGATCTGCCGCCGCGATCGCGGCGCGCCAGATCTCAAGCTTAACTAGTTAGCGGACCGA
  CGCGTTAAGCGGCCGCGAATTCAGATCCACAAGTTTGTACAAAAAAGCAGGCTTGTAAAA
  CGACGGCCAGTAACTATAACGGTCCTAAGGTAGCGAGGCCTGGGTGGCGAATTCGGCACG
  AGGGGAGCGGGAGCGAGCTGGCGGCGCCGTCGGGCGCCGGGCCGGGCCATGGAGCTGTGG
  CCGTGTCTGGCCGCGGCGCTGCTGTTGCTGTTGTTGCTGGTGCAGCTGAGCCGCGCGGCC
  GAGTTCTACGCCAAGGTCGCCCTGTACTGCGCGCTGTGCTTCACGGTGTCCGCCGTGGCC
  TCGCTCGTCTGCCTGCTGCGCCACGGCGGCCGGACGGTGGAGAACATGAGCATCATCGGC
  TGGTTCGTGCGAAGCTTCAAGTACTTTTACGGGCTCCGCTTCGAGGTGCGGGACCCGCGC
  AGGCTGCAGGAGGCCCGTCCCTGTGTCATCGTCTCCAACCACCAGAGCATCCTGGACATG
  ATGGGCCTCATGGAGGTCCTTCCGGAGCGCTGCGTGCAGATCGCCAAGCGGGAGCTGCTC
  TTCCTGGGGCCCGTGGGCCTCATCATGTACCTCGGGGGCGTCTTCTTCATCAACCGGCAG
  CGCTCTAGCACTGCCATGACAGTGATGGCCGACCTGGGCGAGCGCATGGTCAGGAGAACC
  TCAAGTGTGATCTATCCCGAGGTACTCGCACGACCATGGGGACCTGCTGCCCTTTAAGAA
  GGCGCCTTCTACTGCAGTCAGCACAGTGCCCATCTTCCCCGTGGTGTACTCTTCCTTCTC
  TCCCTTACAACACCCAAGAAGAAAGTACTTACAA
• Restriction Sites: Please inquire
• ACCN: NM_006412
• ORF Size: 837 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006412.3, NP_006403.2
• RefSeq Size: 1576
• RefSeq ORF: 837
• Locus ID: 10555
• Domains: Acyltransferase
• Protein Families: Transmembrane
• Protein Pathways: Ether lipid metabolism, Glycerolipid metabolism, Glycerophospholipid metabolism, Metabolic pathways
• Gene Summary: This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).