PPP3CC (NM_005605) Human Untagged Clone

CAT#: SC321511

PPP3CC (untagged)-Human protein phosphatase 3, catalytic subunit, gamma isozyme (PPP3CC)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPP3CC
• Synonyms: CALNA3; CNA3; PP2Bgamma
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005605.3 CACGAGGGCCCGGGCCGCGAGCAGCCGCGGCTGTCCCGGTCGCCACCCTTAGCAGCGGTC
  GAGGTCGGTGCCGAAGCGGTGTTCCCCGCCTTAGCCGCTGGCGCCTCCCAAGAGAGCGGC
  CGGTGGGCCCTCGTCCTGTCAGTGGCGTCGGAGGCCGGCGCTGCGGTGGCCGCGCCCTTC
  TGGTGCTCGGACACCGCTGAGGAGCCGGGGCCGGGCACGGCTGGCTGACGGCTCCGGGCA
  GCTAAGGCTGCCCGAGGAGAAGGCGGCGGCCGCGGCGTAGGCGCACGTCCGGCGGGCTCC
  TGGAGCCTGGAGGAGGCCGAGGGGACCATGTCCGGGAGGCGCTTCCACCTCTCCACCACC
  GACCGCGTCATCAAAGCTGTCCCCTTTCCTCCAACCCAACGGCTTACTTTCAAGGAAGTA
  TTTGAGAATGGGAAACCTAAAGTTGATGTTTTAAAAAACCATTTGGTAAAGGAAGGACGA
  CTGGAAGAGGAAGTAGCCTTAAAGATAATCAATGATGGGGCTGCCATCCTGAGGCAAGAG
  AAGACTATGATAGAAGTAGATGCTCCAATCACAGTATGTGGTGATATTCATGGACAATTC
  TTTGACCTAATGAAGTTATTTGAAGTTGGAGGATCACCTAGTAACACACGCTACCTCTTT
  CTGGGTGACTATGTGGACAGAGGCTATTTCAGTATAGAGTGTGTGCTGTATTTATGGAGT
  TTAAAGATTAATCATCCCAAAACATTGTTTCTGCTTCGGGGAAATCATGAATGCAGGCAT
  CTTACAGACTATTTCACCTTCAAACAGGAATGTCGAATCAAATATTCGGAACAGGTGTAT
  GATGCCTGTATGGAGACATTTGACTGTCTTCCTCTTGCTGCCCTCTTAAACCAGCAGTTT
  CTCTGTGTACATGGAGGAATGTCACCTGAAATTACTTCTTTAGATGACATTAGGAAATTA
  GACAGGTTTACGGAACCTCCCGCCTTTGGACCTGTGTGTGACCTGCTTTGGTCTGATCCC
  TCAGAGGATTATGGCAATGAGAAGACCTTGGAGCACTATACCCACAACACTGTCCGAGGG
  TGCTCTTATTTCTACAGTTACCCTGCAGTTTGTGAATTTTTGCAGAACAATAATTTACTA
  TCAATTATCAGAGCCCATGAAGCCCAAGATGCTGGGTATCGAATGTACAGGAAGAGCCAA
  GCCACAGGCTTTCCATCACTTATTACAATTTTCTCTGCCCCCAATTACCTAGATGTCTAT
  AACAATAAAGCTGCTGTGTTGAAATATGAAAACAATGTCATGAATATCAGGCAGTTTAAC
  TGTTCTCCACACCCCTACTGGCTTCCAAACTTTATGGATGTTTTCACATGGTCTTTGCCT
  TTTGTTGGGGAAAAAGTCACAGAGATGCTGGTAAATGTGCTCAACATATGCTCTGATGAC
  GAACTGATTTCTGATGATGAAGCAGAAGGAAGCACTACAGTTCGTAAGGAGATCATCAGG
  AATAAGATCAGAGCCATTGGGAAGATGGCACGGGTCTTTTCAATTCTTCGGCAAGAAAGT
  GAGAGTGTGCTGACTCTCAAGGGCCTGACTCCCACAGGCACACTCCCTCTGGGCGTCCTC
  TCAGGAGGCAAGCAGACTATCGAGACAGCCACAGTAGAAGCGGTAGAGGCCCGGGAAGCC
  ATCAGAGGGTTCTCGCTTCAGCACAAGATCCGGAGTTTTGAAGAAGCGCGAGGTCTGGAC
  CGAATTAATGAGCGAATGCCACCCCGAAAGGATAGCATACACGCTGGTGGGCCAATGAAA
  TCTGTAACCTCAGCACACTCACATGCTGCGCACAGGAGCGACCAAGGGAAGAAAGCCCAT
  TCATGACTTAGAGTCCTGCCGTGGCTCAGGTGGATCTAAAACTCAAGAACAAATTCTATT
  TATTTATTATTGGAAAATGAAAAGCAACTCAAAACAACTTCAACCTGGAGGTGCATTTAT
  AATTCAGTCTGCATTTATTCTGTAAAAAGGTGACTGTTTTATAAATTCTTTTAATTTATG
  TTCAATATATATAAAAAGTGCATCTGTTTTGTTTTTCCCTTTTTTCTCCATAATTTTAAG
  AAATGAATCTGATTGTTGTCAACACATTTGTGAAGTCTTGTGCTATAAAGGGGAACTTCC
  CCTAATAAAAGGGCCTTGGAAACCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  A
• Restriction Sites: Please inquire
• ACCN: NM_005605
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005605.3, NP_005596.2
• RefSeq Size: 2221 bp
• RefSeq ORF: 1539 bp
• Locus ID: 5533
• Cytogenetics: 8p21.3
• Domains: Metallophos, PP2Ac
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Axon guidance, B cell receptor signaling pathway, Calcium signaling pathway, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway
• Gene Summary: 'Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]'
  Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.