Claudin 4 (CLDN4) (NM_001305) Human Untagged Clone

CAT#: SC321565

CLDN4 (untagged)-Human claudin 4 (CLDN4)


  "NM_001305" in other vectors (6)

Reconstitution Protocol

USD 310.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol CLDN4
Synonyms CPE-R; CPER; CPETR; CPETR1; hCPE-R; WBSCR8
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_001305.3 GGCAGCTGTCGGCTGGAAGGAACTGGTCTGCTCACACTTGCTGGCTTGCGCATCAGGACT
GGCTTTATCTCCTGACTCACGGTGCAAAGGTGCACTCTGCGAACGTTAAGTCCGTCCCCA
GCGCTTGGAATCCTACGGCCCCCACAGCCGGATCCCCTCAGCCTTCCAGGTCCTCAACTC
CCGCGGACGCTGAACAATGGCCTCCATGGGGCTACAGGTAATGGGCATCGCGCTGGCCGT
CCTGGGCTGGCTGGCCGTCATGCTGTGCTGCGCGCTGCCCATGTGGCGCGTGACGGCCTT
CATCGGCAGCAACATTGTCACCTCGCAGACCATCTGGGAGGGCCTATGGATGAACTGCGT
GGTGCAGAGCACCGGCCAGATGCAGTGCAAGGTGTACGACTCGCTGCTGGCACTGCCGCA
GGACCTGCAGGCGGCCCGCGCCCTCGTCATCATCAGCATCATCGTGGCTGCTCTGGGCGT
GCTGCTGTCCGTGGTGGGGGGCAAGTGTACCAACTGCCTGGAGGATGAAAGCGCCAAGGC
CAAGACCATGATCGTGGCGGGCGTGGTGTTCCTGTTGGCCGGCCTTATGGTGATAGTGCC
GGTGTCCTGGACGGCCCACAACATCATCCAAGACTTCTACAATCCGCTGGTGGCCTCCGG
GCAGAAGCGGGAGATGGGTGCCTCGCTCTACGTCGGCTGGGCCGCCTCCGGCCTGCTGCT
CCTTGGCGGGGGGCTGCTTTGCTGCAACTGTCCACCCCGCACAGACAAGCCTTACTCCGC
CAAGTATTCTGCTGCCCGCTCTGCTGCTGCCAGCAACTACGTGTAAGGTGCCACGGCTCC
ACTCTGTTCCTCTCTGCTTTGTTCTTCCCTGGACTGAGCTCAGCGCAGGCTGTGACCCCA
GGAGGGCCCTGCCACGGGCCACTGGCTGCTGGGGACTGGGGACTGGGCAGAGACTGAGCC
AGGCAGGAAGGCAGCAGCCTTCAGCCTCTCTGGCCCACTCGGACAACTTCCCAAGGCCGC
CTCCTGCTAGCAAGAACAGAGTCCACCCTCCTCTGGATATTGGGGAGGGACGGAAGTGAC
AGGGTGTGGTGGTGGAGTGGGGAGCTGGCTTCTGCTGGCCAGGATGGCTTAACCCTGACT
TTGGGATCTGCCTGCATCGGTGTTGGCCACTGTCCCCATTTACATTTTCCCCACTCTGTC
TGCCTGCATCTCCTCTGTTGCGGGTAGGCCTTGATATCACCTCTGGGACTGTGCCTTGCT
CACCGAAACCCGCGCCCAGGAGTATGGCTGAGGCCTTGCCCACCCACCTGCCTGGGAAGT
GCAGAGTGGATGGACGGGTTTAGAGGGGAGGGGCGAAGGTGCTGTAAACAGGTTTGGGCA
GTGGTGGGGGAGGGGGCCAGAGAGGCGGCTCAGGTTGCCCAGCTCTGTGGCCTCAGGACT
CTCTGCCTCACCCGCTTCAGCCCAGGGCCCCTGGAGACTGATCCCCTCTGAGTCCTCTGC
CCCTTCCAAGGACACTAATGAGCCTGGGAGGGTGGCAGGGAGGAGGGGACAGCTTCACCC
TTGGAAGTCCTGGGGTTTTTCCTCTTCCTTCTTTGTGGTTTCTGTTTTGTAATTTAAGAA
GAGCTATTCATCACTGTAATTATTATTATTTTCTACAATAAATGGGACCTGTGCACAGGA
AAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_001305
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001305.3, NP_001296.1
RefSeq Size 1846 bp
RefSeq ORF 630 bp
Locus ID 1364
Cytogenetics 7q11.23
Domains PMP22_Claudin
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
Gene Summary 'The protein encoded by this intronless gene belongs to the claudin family. Claudins are integral membrane proteins that are components of the epithelial cell tight junctions, which regulate movement of solutes and ions through the paracellular space. This protein is a high-affinity receptor for Clostridium perfringens enterotoxin (CPE) and may play a role in internal organ development and function during pre- and postnatal life. This gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems. [provided by RefSeq, Sep 2013]'

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.