RAB6A (NM_002869) Human Untagged Clone

CAT#: SC321570

RAB6A (untagged)-Human RAB6A, member RAS oncogene family (RAB6A), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RAB6A
• Synonyms: RAB6
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002869.4 GGCGGCGGCAGCTGTGGAAGCTCAGGCGCTGCGCGTGAGAGGTCCCAGATACGTCTGCGG
  TTCCGGCTCCGCCACCCTCAGCTTCTCTTCCCCAGGTCTGGGAGCCGAGTGCGGAAGGAG
  GGAACGGCCCTAGCTTTGGGAAGCCAGAGGACACCCCTGGCTCCTGCCGACACCGCCCTC
  CTTCCCTTCCCAGCCGCGGGCCTCGCTCGGTGCTAGGCTACTCTGCCGGGAGGCGGCGGC
  GGCTGCCAGTCTGTGGAGAGTCCTGCTGCCCTCCAGCCGGGCTCCTCCACCGGGCCTTGC
  AGGGGCCGAGAGAGCTCGGTGCCCGCCCTTCCGCTCGCCTTTTTCGTCAGCTGGCTGGAG
  CAGCATCGGTCCGGGAGGTCTCTAGGCTGAGGCGGCGGCCGCTCCTCTAGTTCCACAATG
  TCCACGGGCGGAGACTTCGGGAATCCGCTGAGGAAATTCAAGCTGGTGTTCCTGGGGGAG
  CAAAGCGTTGGAAAGACATCTTTGATCACCAGATTCATGTATGACAGTTTTGACAACACC
  TATCAGGCAACAATTGGCATTGACTTTTTATCAAAAACTATGTACTTGGAGGATCGAACA
  ATCAGGCTTCAGCTGTGGGATACTGCGGGTCAGGAACGTTTCCGTAGCCTCATTCCCAGT
  TACATCCGTGATTCTGCTGCAGCTGTAGTAGTTTACGATATCACAAATGTTAACTCATTC
  CAGCAAACTACAAAGTGGATTGATGATGTCAGAACAGAAAGAGGAAGTGATGTTATCATC
  ATGCTAGTAGGAAATAAAACAGATCTTGCTGACAAGAGGCAAGTGTCAATTGAGGAGGGA
  GAGAGGAAAGCCAAAGAGCTGAATGTTATGTTTATTGAAACTAGTGCAAAAGCTGGATAC
  AATGTAAAGCAGCTCTTTCGACGTGTAGCAGCAGCTTTGCCGGGAATGGAAAGCACACAG
  GACAGAAGCAGAGAAGATATGATTGACATAAAACTGGAAAAGCCTCAGGAGCAACCAGTC
  AGTGAAGGAGGCTGTTCCTGCTAATCTCCCATGTCATCTTCAACCTTCTTCAGAAGCTCA
  CTGCTTTGGCCCCCTTACTCTTTCATTGACTGCAGTGTGAATATTGGCTTGAACCTTTTC
  CCTTCAGTAATAACGTATTGCAATTCATCATTGCTGCCTGTCTCGTGGAGATGATCTATT
  AGCTTCACAAGCACAACAAAAGTCAGTGTCTTCATTATTTATATTTTACAAAAAGCCAAA
  ATATTTCAGCATATTCCAGTGATAACTTTAAAAATTAGATACATTTTCTTAACATTTTTT
  TCTTTTTTAATGTTATGATAATGTACTTCAAAATGATGGAAATCTCAACAGTATGAGTAT
  GGCTTGGTTAACGAGCGCTATGTTCACAGCCTACTTTATCTCTCCTTGCTTTTCTCACCT
  CTCACTTACCCCCATTCCCTATTACCCTATTCTTACCTAGCCTCCCCCGACTTCCTCAAA
  ACAAACAAGAGATGGCAAAGCAGCAGTTCTACCAAGCCCATTGGAATTATCCTTTAATTT
  TACAGATACCACTTGCTGTAGGCTACGGACCAAGATGTCCAAAATTATTCTTGAGCACTG
  ATATAAATTACGGTCTTCTTTGAGGTCAAAATTCAGCCATCATGGTAGGCAGTGCTTGAA
  TGAGAAAAGGCTCCTGGTGCATCTTCAAAATGAGTCCTAAAGAACATACTGAGTACTTAG
  AAGTAGAAGAACATAAGATGTATTTCTGACTAAAACAAATGGCTCTTTCACATGTGCTTT
  ATTAGACTCTGGGAGAGAAAATTAACCAAGTGCTTCAGAACAGGTTTTTAGTATTTAATT
  CTTCACGGTAAGAAAATGAAGTTCTAATGAACTGTTTCTCCCAAGGTTTTAAAATTGTCA
  AGAGTTATTCTGTTTGTTTAAAAAATAAGAAACCTCTTTAAGCAATAGATTTTGCTTGGG
  TTTTCTTTTTTAAAAACATAATACTGTGCAGGCAAGGCACTGTAAAAGTTTTAATTCCTT
  CCAGAAGAACCAGTGGAAGAATTTAAATTTGGCGCTACGATCAAAACTACTGAATTAGTA
  GAAATAATGATGTCTAAAGCTTACCAACAAAAGAACCCTCAGCAGAATAACAAAAACTTT
  GCTCAGGACATTTGAGGTCAAATTGAAGACGGAAACCGGAAACCGTTTTCTTGTAAGCCC
  CTAGAGGCAGATCAGGTAAAGCATACATAGTAGAGGGAAAGGAGAGAATGGAAATAAAAC
  TCAATATTATGCAGATTTATGCCTTATTTTTTAGCATTTTTTAAGGTTGGGTCTTTCAGG
  CTGGTTTTGGTTTGTATTAGATCTGTATAGTTTAATTAACTGGTGATTTAGTTTTATATT
  TAAGCTACAATTAATCTTTTTTCTTTGGTGATATTTATTTCTTTGCCTTTTTTTTTTTTA
  ACAACTTTCAATCTTCAGATGTTTCGTTGAATCTATTTAGAGCTTCACCATGGCAATATG
  TATTTCCCTTAAAACACTGCAAACAAATATACTAGGAGTGTGCCCTTTTAATCTTTACTA
  GTTATTGTGAGATTGCTGTGTAAGCTAATAAACACATTTGTAAATACATTGTTTGCAGGA
  CGAAAACTTCTGAGTTACAGCTCAGGAAAAGCCTGCTGAATTTATGTTGTAAGCATTACT
  TAACACAGTATAAAGATGAAAAGACAACAAAAATATCTTCATACTTCCTCATCCCCTCAT
  TGGAACAAAAACCTTAAACTGGGAGAACCTTAGTCCCCTCTCTTTCCTCTTCCTCCTCCA
  CTTCCCACTTATTGTCACCTTGTAATATTCAGAGAGCACTTGGATTATGGATCTGAATAG
  AGAAATGCTTACAGATAATCATTAGCCCACATACCAGTAACTTATACTTAAAGATGGGAT
  GGAGTTGTAAAGTGCTTTTATAATACAATATAATTGTTAAAGGCAAGGGTTGACTCTTTG
  TTTTATTTTGACATGGCATGTCCTGAAATAAATATTGATTCAATATGGCAAAAAAAAAAA
  AAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_002869
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002869.4, NP_002860.2
• RefSeq Size: 3419 bp
• RefSeq ORF: 627 bp
• Locus ID: 5870
• Cytogenetics: 11q13.4
• Domains: ras, RAN, RAS, RHO, RAB
• Protein Families: Druggable Genome
• Gene Summary: 'This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]'
  Transcript Variant: This variant (1) encodes isoform a, also known as RAB6A' or RAB6C.