SP110 (NM_004510) Human Untagged Clone

CAT#: SC321631

SP110 (untagged)-Human SP110 nuclear body protein (SP110), transcript variant b

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SP110
• Synonyms: IFI41; IFI75; IPR1; VODI
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004510.2 GTTTTGCCTGCTAGCATCTCCCTGTAACTCTCCCAATCTTGAGGAGTGATCCCTGTCCCA
  GCCCCTGGAAAGGGGCAGGAACGACAAACTCAAAGTCCAGGATGTTCACCATGACAAGAG
  CCATGGAAGAGGCTCTTTTTCAGCACTTCATGCACCAGAAGCTGGGGATCGCCTATGCCA
  TACACAAGCCATTTCCCTTCTTTGAAGGCCTCCTAGACAACTCCATCATCACTAAGAGAA
  TGTACATGGAATCTCTGGAAGCCTGTAGAAATTTGATCCCTGTATCCAGAGTGGTGCACA
  ACATTCTCACCCAACTGGAGAGGACTTTTAACCTGTCTCTTCTGGTGACATTGTTCAGTC
  AAATTAACCTGCGTGAATATCCCAATCTGGTGACGATTTACAGAAGCTTCAAACGTGTTG
  GTGCTTCCTATGAACGGCAGAGCAGAGACACACCAATCCTACTTGAAGCCCCAACTGGCC
  TAGCAGAAGGAAGCTCCCTCCATACCCCACTGGCGCTGCCCCCACCACAACCCCCTCAAC
  CAAGCTGTTCACCCTGTGCGCCAAGAGTCAGTGAGCCTGGAACATCCTCCCAGCAAAGCG
  ATGAGATCCTGAGTGAGTCGCCCAGCCCATCTGACCCTGTCCTGCCTCTCCCTGCACTCA
  TCCAGGAAGGAAGAAGCACTTCAGTGACCAATGACAAGTTAACATCCAAAATGAATGCGG
  AAGAAGACTCAGAAGAGATGCCCAGCCTCCTCACTAGCACTGTGCAAGTGGCCAGTGACA
  ACCTGATCCCCCAAATAAGAGATAAAGAAGACCCTCAAGAGATGCCCCACTCTCCCTTGG
  GCTCTATGCCAGAGATAAGAGATAATTCTCCAGAACCAAATGACCCAGAAGAGCCCCAGG
  AGGTGTCCAGCACACCTTCAGACAAGAAAGGAAAGAAAAGAAAAAGATGTATCTGGTCAA
  CTCCAAAAAGGAGACATAAGAAAAAAAGCCTCCCAAGAGCCTTATCTAGACACGGAATCC
  AAAAGAAGCTCAAAAGGGTGGATCAGGTTCCTCAAAAGAAAGATGACTCAACTTGTAACT
  CCACGGTAGAGACAAGGGCCCAAAAGGCGAGAACTGAATGTGCCCGAAAGTCGAGATCAG
  AGGAGATCATTGATGGCACTTCAGAAATGAATGAAGGAAAGAGGTCCCAGAAGACGCCTA
  GTACACCACGAAGGGTCACACAAGGGGCAGCCTCACCTGGGCATGGCATCCAAGAGAAGC
  TCCAAGTGGTGGATAAGGTGACTCAAAGGAAAGACGACTCAACCTGGAACTCAGAGGTCA
  TGATGAGGGTCCAAAAGGCAAGAACTAAATGTGCCCGAAAGTCCAGATCGAAAGAAAAGA
  AAAAGGAGAAAGATATCTGTTCAAGCTCAAAAAGGAGATTTCAGAAAAATATTCACCGAA
  GAGGAAAACCCAAAAGTGACACTGTGGATTTTCACTGTTCTAAGCTCCCCGTGACCTGTG
  GTGAGGCGAAAGGGATTTTATATAAGAAGAAAATGAAACACGGATCCTCAGTGAAGTGCA
  TTCGGAATGAGGATGGAACTTGGTTAACACCAAATGAATTTGAAGTCGAAGGAAAAGGAA
  GGAACGCAAAGAACTGGAAACGGAATATACGTTGTGAAGGAATGACCCTAGGAGAGCTGC
  TGAAGAGTGGACTTTTGCTCTGTCCTCCAAGAATAAATCTCAAGAGAGAGTTAAATAGCA
  AGTGAATTTCTACTACCCTCTCAGTCACCATGTTGCAGACTTTCCCTGTCTGGAGGCTCA
  CCTTAGAGCTTCTGAGTTTCCAAGCTCTGAGTCACCTCCACATTTGGGCATGGCATCTTC
  AAAACAATTAATTTGCATAGTTAATTTGGGATGGGGAAGCAAATGACTCTAAAATAAAAA
  TTAAATGAAAAAGCTCAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_004510
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004510.2, NP_004501.2
• RefSeq Size: 1962 bp
• RefSeq ORF: 1650 bp
• Locus ID: 3431
• Cytogenetics: 2q37.1
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: 'The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (b) uses an alternate exon for the 3' coding region and 3' UTR, as compared to variant c. The encoded protein (isoform b) has a shorter and distinct C-terminus and lacks the bromodomain when it is compared to isoform c.