MDC (CCL22) (NM_002990) Human Untagged Clone

CAT#: SC321689

CCL22 (untagged)-Human chemokine (C-C motif) ligand 22 (CCL22)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CCL22
• Synonyms: A-152E5.1; ABCD-1; DC/B-CK; MDC; SCYA22; STCP-1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002990.3 CAGGACAGAGCATGGCTCGCCTACAGACTGCACTCCTGGTTGTCCTCGTCCTCCTTGCTG
  TGGCGCTTCAAGCAACTGAGGCAGGCCCCTACGGCGCCAACATGGAAGACAGCGTCTGCT
  GCCGTGATTACGTCCGTTACCGTCTGCCCCTGCGCGTGGTGAAACACTTCTACTGGACCT
  CAGACTCCTGCCCGAGGCCTGGCGTGGTGTTGCTAACCTTCAGGGATAAGGAGATCTGTG
  CCGATCCCAGAGTGCCCTGGGTGAAGATGATTCTCAATAAGCTGAGCCAATGAAGAGCCT
  ACTCTGATGACCGTGGCCTTGGCTCCTCCAGGAAGGCTCAGGAGCCCTACCTCCCTGCCA
  TTATAGCTGCTCCCCGCCAGAAGCCTGTGCCAACTCTCTGCATTCCCTGATCTCCATCCC
  TGTGGCTGTCACCCTTGGTCACCTCCGTGCTGTCACTGCCATCTCCCCCCTGACCCCTCT
  AACCCATCCTCTGCCTCCCTCCCTGCAGTCAGAGGGTCCTGTTCCCATCAGCGATTCCCC
  TGCTTAAACCCTTCCATGACTCCCCACTGCCCTAAGCTGAGGTCAGTCTCCCAAGCCTGG
  CATGTGGCCCTCTGGATCTGGGTTCCATCTCTGTCTCCAGCCTGCCCACTTCCCTTCATG
  AATGTTGGGTTCTAGCTCCCTGTTCTCCAAACCCATACTACACATCCCACTTCTGGGTCT
  TTGCCTGGGATGTTGCTGACACTCAGAAAGTCCCACCACCTGCACATGTGTAGCCCCACC
  AGCCCTCCAAGGCATTGCTCGCCCAAGCAGCTGGTAATTCCATTTCATGTATTAGATGTC
  CCCTGGCCCTCTGTCCCCTCTTAATAACCCTAGTCACAGTCTCCGCAGATTCTTGGGATT
  TGGGGGTTTTCTCCCCCACCTCTCCACTAGTTGGACCAAGGTTTCTAGCTAAGTTACTCT
  AGTCTCCAAGCCTCTAGCATAGAGCACTGCAGACAGGCCCTGGCTCAGAATCAGAGCCCA
  GAAAGTGGCTGCAGACAAAATCAATAAAACTAATGTCCCTCCCCTCTCCCTGCCAAAAGG
  CAGTTACATATCAATACAGAGACTCAAGGTCACTAGAAATGGGCCAGCTGGGTCAATGTG
  AAGCCCCAAATTTGCCCAGATTCACCTTTCTTCCCCCACTCCCTTTTTTTTTTTTTTTTT
  GAGATGGAGTTTCGCTCTTGTCACCCACGCTGGAGTGCAATGGTGTGGTCTTGGCTTATT
  GAAGCCTCTGCCTCCTGGGTTCAAGTGATTCTCTTGCCTCAGCCTCCTGAGTAGCTGGGA
  TTACAGGTTCCTGCTACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGAGGCTTC
  ACCATGTTGGCCAGGCTGGTCTCGAACTCCTGTCCTCAGGTAATCCGCCCACCTCAGCCT
  CCCAAAGTGCTGGGATTACAGGCGTGAGCCACAGTGCCTGGCCTCTTCCCTCTCCCCACT
  CCCCCCCCCAACTTTTTTTTTTTTTTTATGGCAGGGTCTCACTCTGTCGCCCAGGCTGGA
  GTGCAGTGGCGTGATCTCGGCTCACTACAACCTCGACCTCCTGGGTTCAAGTGATTCTCC
  CACCCCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGTGCCACTACGGCTGGCTAATTTT
  TGTATTTTTAGTAGAGACAGGTTTCACCATATTGGCCAGGCTGGTCTTGAACTCCTGACC
  TCAAGTGATCCACCTTCCTTGTGCTCCCAAAGTGCTGAGATTACAGGCGTGAGCTATCAC
  ACCCAGCCTCCCCCTTTTTTTCCTAATAGGAGACTCCTGTACCTTTCTTCGTTTTACCTA
  TGTGTCGTGTCTGCTTACATTTCCTTCTCCCCTCAGGCTTTTTTTGGGTGGTCCTCCAAC
  CTCCAATACCCAGGCCTGGCCTCTTCAGAGTACCCCCCATTCCACTTTCCCTGCCTCCTT
  CCTTAAATAGCTGACAATCAAATTCATGCTATGGTGTGAAAGACTACCTTTGACTTGGTA
  TTATAAGCTGGAGTTATATATGTATTTGAAAACAGAGTAAATACTTAAGAGGCCAAATAG
  ATGAATGGAAGAATTTTAGGAACTGTGAGAGGGGGACAAGGTGGAGCTTTCCTGGCCCTG
  GGAGGAAGCTGGCTGTGGTAGCGTAGCGCTCTCTCTCTCTGTCTGTGGCAGGAGGCAAAG
  AGTAGGGTGTAATTGAGTGAAGGAATCCTGGGTAGAGACCATTCTCAGGTGGTTGGGCCA
  GGCTAAAGACTGGGATTTGGGTCTATCTATGCCTTTCTGGCTGATTTTTGTAGAGACGGG
  GTTTTGCCATGTTACCCAGGCTGGTCTCAAACTCCTGGGCTCAAGCGATCCTCCTGGCTC
  AGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGTCACTGCGCCTGGCTTCCTCTTCCTCT
  TGAGAAATATTCTTTTCATACAGCAAGTATGGGACAGCAGTGTCCCAGGTAAAGGACATA
  AATGTTACAAGTGTCTGGTCCTTTCTGAGGGAGGCTGGTGCCGCTCTGCAGGGTATTTGA
  ACCTGTGGAATTGGAGGAGGCCATTTCACTCCCTGAACCCAGCCTGACAAATCACAGTGA
  GAATGTTCACCTTATAGGCTTGCTGTGGGGCTCAGGTTGAAAGTGTGGGGAGTGACACTG
  CCTAGGCATCCAGCTCAGTGTCATCCAGGGCCTGTGTCCCTCCCGAACCCAGGGTCAACC
  TGCCTGCCACAGGCACTAGAAGGACGAATCTGCCTACTGCCCATGAACGGGGCCCTCAAG
  CGTCCTGGGATCTCCTTCTCCCTCCTGTCCTGTCCTTGCCCCTCAGGACTGCTGGAAAAT
  AAATCCTTTAAAATAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_002990
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002990.3, NP_002981.2
• RefSeq Size: 2918 bp
• RefSeq ORF: 282 bp
• Locus ID: 6367
• Cytogenetics: 16q21
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Protein Pathways: Chemokine signaling pathway, Cytokine-cytokine receptor interaction
• Gene Summary: 'This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. [provided by RefSeq, Sep 2014]'