ZC3H8 (NM_032494) Human Untagged Clone

CAT#: SC321774

ZC3H8 (untagged)-Human zinc finger CCCH-type containing 8 (ZC3H8)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZC3H8
• Synonyms: Fliz1; ZC3HDC8
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_032494.1 CTCTGTAGCTTCCCGGCTCGCGAAAGGGAGGACCTGTCTGGGTCATGGATTTTGAGAATC
  TTTTCTCAAAACCCCCCAACCCGGCCCTCGGCAAAACGGCCACGGACTCTGACGAAAGAA
  TCGATGATGAAATAGATACAGAAGTTGAAGAAACACAAGAAGAGAAAATTAAACTGGAGT
  GCGAGCAAATTCCCAAAAAATTTAGACACTCTGCAATATCACCAAAAAGTTCGCTGCATA
  GAAAATCAAGAAGTAAGGACTATGATGTATATAGTGATAATGATATCTGCAGTCAGGAAT
  CAGAAGATAATTTTGCCAAAGAGCTTCAACAGTACATACAAGCCAGAGAAATGGCAAATG
  CTGCTCAACCTGAAGAATCTACAAAGAAAGAAGGAGTAAAAGATACCCCACAGGCTGCTA
  AACAAAAAAATAAAAATCTTAAAGCTGGTCACAAGAATGGCAAACAGAAGAAAATGAAGC
  GAAAATGGCCTGGCCCTGGAAACAAAGGATCAAATGCTTTGCTGAGGAACAGCGGCTCAC
  AGGAAGAGGACGGTAAACCTAAAGAGAAGCAGCAGCATTTGAGTCAGGCATTCATCAACC
  AACATACAGTGGAACGCAAGGGAAAACAAATTTGTAAATATTTTCTTGAAAGGAAATGTA
  TTAAGGGAGACCAGTGTAAATTTGATCATGATGCAGAGATAGAAAAGAAAAAGGAAATGT
  GTAAGTTTTATGTACAAGGATATTGTACCAGAGGTGAAAACTGTCTGTATTTGCATAATG
  AATATCCTTGTAAGTTTTACCATACAGGAACAAAATGTTATCAGGGAGAATACTGCAAGT
  TTTCTCATGCTCCACTGACTCCTGAAACACAAGAATTGTTGGCTAAAGTTTTGGATACTG
  AAAAGAAGTCATGTAATAAAATAGACATAAAAAGGTAGCAATGTACAGATAAAGAGTACT
  TTAACGCCCATGCGTGTTCAAGACTGTTCAAGACTGGTGATTTGGAGTAGTTTACAAGAT
  TCCTCATTCAGAGTGCCCTCTTGTGTGACTGGGGTGATGTGCAGCTTCCATAATGGATGG
  GACAGAGAGCTGGGATCTAATGTACAAGTGAAGGGCTTGGTCTTCCCTGAGACATTCCAG
  CCATTGGAATAGGAGAGGAGCATATATGGCAGAGGTGATGGCTGGTGGGTAAATGTGATA
  GTAAATTGTAGAAACCTCTTCTGATTGATTGGATTTCCTTAATAAAATCGGAAGCAAGGT
  TAGGCTGAGTGAGGGTGAGTAAAGAGGTAGAGGAGGTTTGAGGAGAGAGAACTGCTCGGA
  AGACATTGGTAGATGGACCATAAAAACAGAGTTAGTTCTCTTTATGACATTAAATAGTTT
  TACAACATATTTTTAATGGTTCACAATTTCATTTTAGGGCTTAAAATAAATTATGGTTCT
  ATGATTTTTTTAAACCAGTTTCCTATTGTTAGACATTTGTTTCCAGTTTCTTACTATTAT
  AAATAAAGTGAAACAATATCTCTTACTATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_032494.1 unedited
  GACCATTGTATACGACTCCTATAGGGCGGCGCGGCGATCGCGGCGCGCCGGTACCGGTCC
  GGAATTCCCGGGATCTCTGTAGCTTCCCGGCTCGCGAAAGGGAGGACCTGTCTGGGTCAT
  GGATTTTGAGAATCTTTTCTCAAAACCCCCCAACCCGGCCCTCGGCAAAACGGCCACGGA
  CTCTGACGAAAGAATCGATGATGAAATAGATACAGAAGTTGAAGAAACACAAGAAGAGAA
  AATTAAACTGGAGTGCGAGCAAATTCCCAAAAAATTTAGACACTCTGCAATATCACCAAA
  AAGTTCGCTGCATAGAAAATCAAGAAGTAAGGACTATTTATGTATATAGTGATAATGATA
  TCTGCAGTCAGGAATCAGAAGATAATTTTGCCAAAGAGCTTCAACAGTACATACAAGCCA
  GAGAAATGGCAAATGCTGCTCAACCTGAAGAATCTACAAAGAAAGAAGGAGTAAAAGATA
  CCCCACAGGCTGCTAAACAAAAAAATAAAAATCTTAAAGCTGGTCACAAGAATGGCAAAC
  AGAAGAAAATGAAGCGAAAATGGCCTGGCCCTGGAAACAAAGGATCAAATGCTTTGCTGA
  GGAACAGCGGCTCACAGGAAGAGGACGGTAAACCTAAAGAGAAGCAGCAGCATTTGAGTC
  AGCATTCATCAACCAACATACAGTGGAACGCAAGGGAAAACAAATTTGTAAATATTTTCT
  TGAAAGGAAATGTATTAAGGAGACCAGTGTAAATTTGATCATGATGCAGAGATAGAAAAG
  AAAAGGAAATGTGTAAGTTTTATGTACAAGGATATTTGTACCAGAGGTGAAAACTGTTCT
  GTATTTGCATAATGAATATCCTTGTAAGTTTACCATACAGGAACAAAAATGTTATCAAGG
  AAGAAATACTGCAGTTTTCTCATGCCTCCACTGACTCCTGAAACACAAGATGTGCTAAGT
  TGATCTGAAAGAAGTCTGTTATAAAATAGACTAAAGGTGACCATGTGTCCGGTTGAG
• Restriction Sites: Please inquire
• ACCN: NM_032494
• ORF Size: 876 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_032494.1, NP_115883.1
• RefSeq Size: 1595
• RefSeq ORF: 876
• Locus ID: 84524
• Domains: zf-CCCH
• Gene Summary: Acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5'-AGGTCTC-3' sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis. [UniProtKB/Swiss-Prot Function]