LILRB2 (NM_005874) Human Untagged Clone

CAT#: SC321856

LILRB2 (untagged)-Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 (LILRB2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LILRB2
• Synonyms: CD85D; ILT-4; ILT4; LIR-2; LIR2; MIR-10; MIR10
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005874.1 GACGGCACAGCCAGATGCGAGATGCGTCTCTGCTGATCTGAGTCTGCCTGCAGCATGGAC
  CTGGGTCTTCCCTGAAGCATCTCCAGGGCTGGAGGGACGACTGCCATGCACCGAGGGCTC
  ATCCATCCGCAGAGCAGGGCAGTGGGAGGAGACGCCATGACCCCCATCGTCACAGTCCTG
  ATCTGTCTCGGGCTGAGTCTGGGCCCCAGGACCCACGTGCAGACAGGGACCATCCCCAAG
  CCCACCCTGTGGGCTGAGCCAGACTCTGTGATCACCCAGGGGAGTCCCGTCACCCTCAGT
  TGTCAGGGGAGCCTTGAAGCCCAGGAGTACCGTCTATATAGGGAGAAAAAATCAGCATCT
  TGGATTACACGGATACGACCAGAGCTTGTGAAGAACGGCCAGTTCCACATCCCATCCATC
  ACCTGGGAACACACAGGGCGATATGGCTGTCAGTATTACAGCCGCGCTCGGTGGTCTGAG
  CTCAGTGACCCCCTGGTGCTGGTGATGACAGGAGCCTACCCAAAACCCACCCTCTCAGCC
  CAGCCCAGCCCTGTGGTGACCTCAGGAGGAAGGGTGACCCTCCAGTGTGAGTCACAGGTG
  GCATTTGGCGGCTTCATTCTGTGTAAGGAAGGAGAAGATGAACACCCACAATGCCTGAAC
  TCCCAGCCCCATGCCCGTGGGTCGTCCCGCGCCATCTTCTCCGTGGGCCCCGTGAGCCCG
  AATCGCAGGTGGTCGCACAGGTGCTATGGTTATGACTTGAACTCTCCCTATGTGTGGTCT
  TCACCCAGTGATCTCCTGGAGCTCCTGGTCCCAGGTGTTTCTAAGAAGCCATCACTCTCA
  GTGCAGCCGGGTCCTGTCGTGGCCCCTGGGGAAAGCCTGACCCTCCAGTGTGTCTCTGAT
  GTCGGCTATGACAGATTTGTTCTGTACAAGGAGGGGGAACGTGACCTTCGCCAGCTCCCT
  GGCCGGCAGCCCCAGGCTGGGCTCTCCCAGGCCAACTTCACCCTGGGCCCTGTGAGCCGC
  TCCTACGGGGGCCAGTACAGATGCTACGGTGCATACAACCTCTCCTCCGAGTGGTCGGCC
  CCCAGCGACCCCCTGGACATCCTGATCACAGGACAGATCCATGGCACACCCTTCATCTCA
  GTGCAGCCAGGCCCCACAGTGGCCTCAGGAGAGAACGTGACCCTGCTGTGTCAGTCATGG
  CGGCAGTTCCACACTTTCCTTCTGACCAAGGCGGGAGCAGCTGATGCCCCACTCCGTCTA
  AGATCAATACACGAATATCCTAAGTACCAGGCTGAATTCCCCATGAGTCCTGTGACCTCA
  GCCCACGCGGGGACCTACAGGTGCTACGGCTCACTCAACTCCGACCCCTACCTGCTGTCT
  CACCCCAGTGAGCCCCTGGAGCTCGTGGTCTCAGGACCCTCCATGGGTTCCAGCCCCCCA
  CCCACCGGTCCCATCTCCACACCTGCAGGCCCTGAGGACCAGCCCCTCACCCCCACTGGG
  TCGGATCCCCAAAGTGGTCTGGGAAGGCACCTGGGGGTTGTGATCGGCATCTTGGTGGCC
  GTCGTCCTACTGCTCCTCCTCCTCCTCCTCCTCTTCCTCATCCTCCGACATCGACGTCAG
  GGCAAACACTGGACATCAACCCAGAGAAAGGCTGATTTCCAACATCCTGCAGGGGCTGTG
  GGGCCAGAGCCCACAGACAGAGGCCTGCAGTGGAGGTCCAGCCCAGCTGCCGACGCCCAG
  GAAGAAAACCTCTATGCTGCCGTGAAGGACACACAGCCTGAAGATGGGGTGGAGATGGAC
  ACTCGGGCTGCTGCATCTGAAGCCCCCCAGGATGTGACCTACGCCCAGCTGCACAGCTTG
  ACCCTCAGACGGAAGGCAACTGAGCCTCCTCCATCCCAGGAAGGGGAACCTCCAGCTGAG
  CCCAGCATCTACGCCACCCTGGCCATCCACTAGCCCGGAGGGTACGCAGACTCCACACTC
  AGTAGAAGGAGACTCAGGACTGCTGAAGGCACGGGAGCTGCCCCCAGTGGACACCAATGA
  ACCCCAGTCAGCCTGGACCCCTAACAAAGACCATGAGGAGATGCTGGGAACTTTGGGACT
  CACTTGATTCTGCAGTCGAAATAACTAATATCCCTACATTTTTTAATTAAAGCAACAGAC
  TTCTCAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005874.1 unedited
  GGCCTTTGTATACGACTCCTATAGGGCGGCGCGGCTGATCGCGGCGCGCCGGTACCGGTC
  CGGAATTCCCGGGATGACGGCACAGCCAGATGCGAGATGCGTCTCTGCTGATCTGAGTCT
  GCCTGCAGCATGGACCTGGGTCTTCCCTGAAGCATCTCCAGGGCTGGAGGGACGACTGCC
  ATGCACCGAGGGCTCATCCATCCGCAGAGCAGGGCAGTGGGAGGAGACGCCATGACCCCC
  ATCGTCACAGTCCTGATCTGTCTCGGGCTGAGTCTGGGCCCCAGGACCCACGTGCAGACA
  GGGACCATCCCCAAGCCCACCCTGTGGGCTGTGTTTTTACTCTGTGATCACCCAGGGGAG
  TCCCGTCACCCTCAGTTGTCAGGGGAGCCTTGAAGCCCAGGAGTACCGTCTATATAGGGA
  GAAAAAATCAGCATCTTGGATTACACGGATACGACCAGAGCTTGTGAAGAACGGCCAGTT
  CCACATCCCATCCATCACCTGGGAACACACAGGGCGATATGGCTGTCAGTATTACAGCCG
  CGCTCGGTGGTCTGAGCTCAGTGACCCCCTGGTGCTGGTGATGACAGGAGCCTACCCAAA
  ACCCACCCTCTCAGCCCAGCCCAGCCCTGTGGTGACCTCAGAGGAAAGGGTGACCCTCCA
  GTGTGAGTCACAGGTGGCATTTGGCGGCTTCATTCTGTGTAAGGAAGGAGAAGATGAACA
  CCCACAATGCCTGAACTCCCAGCCCCATGCCCGTGGTCGTCCCGCGCCATCTTCTCCGTG
  GGCCCCGTGAGCCCGAATCGCAGGTGGTCGACAGGTGCTATGGTATGACTTGAACTCTCC
  CTTATGTTGTGGTCTTCACCCAGTGATCTCTGAGCTCTGTCCCAGGTGTTTCTAGAGCAT
  CACTCTCATGCAGCGGTCTGTCTGCCCTTGGGAAAGGCTGACCTCATGGTTCTCTGAGTT
  CGGCTATGACGATTTGTTCTGTACAAGGAAGGGAACCGTGAACT
• Restriction Sites: Please inquire
• ACCN: NM_005874
• ORF Size: 1797 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005874.1, NP_005865.1
• RefSeq Size: 2221
• RefSeq ORF: 1797
• Locus ID: 10288
• Domains: ig, IGc2, IG
• Protein Families: Transmembrane
• Gene Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).