SOX9 (NM_000346) Human Untagged Clone

CAT#: SC321884

SOX9 (untagged)-Human SRY (sex determining region Y)-box 9 (SOX9)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SOX9
• Synonyms: CMD1; CMPD1; SRA1; SRXX2; SRXY10
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000346.2 ATCGTCGACCCACGCGTCCGAAGCGGAGCTCGAAACTGACTGGAAACTTCAGTGGCGCGG
  AGACTCGCCAGTTTCAACCCCGGAAACTTTTCTTTGCAGGAGGAGAAGAGAAGGGGTGCA
  AGCGCCCCCACTTTTGCTCTTTTTCCTCCCCTCCTCCTCCTCTCCAATTCGCCTCCCCCC
  ACTTGGAGCGGGCAGCTGTGAACTGGCCACCCCGCGCCTTCCTAAGTGCTCGCCGCGGTA
  GCCGGCCGACGCGCCAGCTTCCCCGGGAGCCGCTTGCTCCGCATCCGGGCAGCCGAGGGG
  AGAGGAGCCCGCGCCTCGAGTCCCCGAGCCGCCGCGGCTTCTCGCCTTTCCCGGCCACCA
  GCCCCCTGCCCCGGGCCCGCGTATGAATCTCCTGGACCCCTTCATGAAGATGACCGACGA
  GCAGGAGAAGGGCCTGTCCGGCGCCCCCAGCCCCACCATGTCCGAGGACTCCGCGGGCTC
  GCCCTGCCCGTCGGGCTCCGGCTCGGACACCGAGAACACGCGGCCCCAGGAGAACACGTT
  CCCCAAGGGCGAGCCCGATCTGAAGAAGGAGAGCGAGGAGGACAAGTTCCCCGTGTGCAT
  CCGCGAGGCGGTCAGCCAGGTGCTCAAAGGCTACGACTGGACGCTGGTGCCCATGCCGGT
  GCGCGTCAACGGCTCCAGCAAGAACAAGCCGCACGTCAAGCGGCCCATGAACGCCTTCAT
  GGTGTGGGCGCAGGCGGCGCGCAGGAAGCTCGCGGACCAGTACCCGCACTTGCACAACGC
  CGAGCTCAGCAAGACGCTGGGCAAGCTCTGGAGACTTCTGAACGAGAGCGAGAAGCGGCC
  CTTCGTGGAGGAGGCGGAGCGGCTGCGCGTGCAGCACAAGAAGGACCACCCGGATTACAA
  GTACCAGCCGCGGCGGAGGAAGTCGGTGAAGAACGGGCAGGCGGAGGCAGAGGAGGCCAC
  GGAGCAGACGCACATCTCCCCCAACGCCATCTTCAAGGCGCTGCAGGCCGACTCGCCACA
  CTCCTCCTCCGGCATGAGCGAGGTGCACTCCCCCGGCGAGCACTCGGGGCAATCCCAGGG
  CCCACCGACCCCACCCACCACCCCCAAAACCGACGTGCAGCCGGGCAAGGCTGACCTGAA
  GCGAGAGGGGCGCCCCTTGCCAGAGGGGGGCAGACAGCCCCCTATCGACTTCCGCGACGT
  GGACATCGGCGAGCTGAGCAGCGACGTCATCTCCAACATCGAGACCTTCGATGTCAACGA
  GTTTGACCAGTACCTGCCGCCCAACGGCCACCCGGGGGTGCCGGCCACGCACGGCCAGGT
  CACCTACACGGGCAGCTACGGCATCAGCAGCACCGCGGCCACCCCGGCGAGCGCGGGCCA
  CGTGTGGATGTCCAAGCAGCAGGCGCCGCCGCCACCCCCGCAGCAGCCCCCACAGGCCCC
  GCCGGCCCCGCAGGCGCCCCCGCAGCCGCAGGCGGCGCCCCCACAGCAGCCGGCGGCACC
  CCCGCAGCAGCCACAGGCGCACACGCTGACCACGCTGAGCAGCGAGCCGGGCCAGTCCCA
  GCGAACGCACATCAAGACGGAGCAGCTGAGCCCCAGCCACTACAGCGAGCAGCAGCAGCA
  CTCGCCCCAACAGATCGCCTACAGCCCCTTCAACCTCCCACACTACAGCCCCTCCTACCC
  GCCCATCACCCGCTCACAGTACGACTACACCGACCACCAGAACTCCAGCTCCTACTACAG
  CCACGCGGCAGGCCAGGGCACCGGCCTCTACTCCACCTTCACCTACATGAACCCCGCTCA
  GCGCCCCATGTACACCCCCATCGCCGACACCTCTGGGGTCCCTTCCATCCCGCAGACCCA
  CAGCCCCCAGCACTGGGAACAACCCGTCTACACACAGCTCACTCGACCTTGAGGAGGCCT
  CCCACGAAGGGCGAAGATGGCCGAGATGATCCTAAAAATAACCGAAGAAAGAGAGGACCA
  ACCAGAATTCCCTTTGGACATTTGTGTTTTTTTGTTTTTTTATTTTGTTTTGTTTTTTCT
  TCTTCTTCTTCTTCCTTAAAGACATTTAAGCTAAAGGCAACTCGTACCCAAATTTCCAAG
  ACACAAACATGACCTATCCAAGCGCATTACCCACTTGTGGCCAATCAGTGGCCAGGCCAA
  CCTTGGCTAAATGGAGCAGCGAAATCAACGAGAAACTGGACTTTTTAAACCCTCTTCAGA
  GCAAGCGTGGAGGATGATGGAGAATCGTGTGATCAGTGTGCTAAATCTCTCTGCCTGTTT
  GGACTTTGTAATTATTTTTTTAGCAGTAATTAAAGAAAAAAGTCCTCTGTGAGGAATATT
  CTCTATTTTAAATATTTTTAGTATGTACTGTGTATGATTCATTACCATTTTGAGGGGATT
  TATACATATTTTTAGATAAAATTAAATGCTCTTATTTTTCCAACAGCTAAACTACTCTTA
  GTTGAACAGTGTGCCCTAGCTTTTCTTGCAACCAGAGTATTTTTGTACAGATTTGCTTTC
  TCTTACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_000346
• Insert Size: 2600 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: no
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000346.2, NP_000337.1
• RefSeq Size: 3935 bp
• RefSeq ORF: 1530 bp
• Locus ID: 6662
• Cytogenetics: 17q24.3
• Domains: HMG
• Protein Families: Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
• Gene Summary: 'The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq, Jul 2008]'