ZCCHC8 (NM_017612) Human Untagged Clone

CAT#: SC321940

ZCCHC8 (untagged)-Human zinc finger, CCHC domain containing 8 (ZCCHC8)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZCCHC8
• Synonyms: DKFZp434E2220
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_017612.2 CGCCTTCCAACCTTCTTCCCCAAGCCCTGGTGGCCGGCTCCGCCTCTTCTCGAATCTTTT
  CCACAGCCCAAAATGGCCGCAGAGGTGTATTTTGGCGATCTAGAGCTCTTCGAGCCGTTC
  GACCACCCAGAGGAGTCGATTCCGAAGCCCGTTCACACTCGCTTCAAGGACGACGACGGC
  GACGAGGAGGACGAAAATGGGGTCGGCGACGCGGAGCTACGGGAGCGGCTTCGGCAGTGC
  GAGGAGACCATCGAGCAGCTCCGCGCCGAGAATCAAGAACTTAAACGAAAATTGAACATT
  CTGACTCGACCGAGTGGAATATTGGTGAACGATACTAAGTTAGATGGACCTATATTACAG
  ATTCTATTCATGAACAATGCTATTTCAAAGCAATATCATCAAGAAATAGAGGAATTTGTA
  TCAAATTTAGTAAAAAGATTTGAGGAACAGCAGAAAAATGATGTGGAAAAGACTTCCTTT
  AATCTTTTGCCCCAGCCATCCAGTATTGTGCTAGAGGAGGACCACAAAGTGGAAGAGTCC
  TGTGCCATTAAAAACAACAAGGAAGCTTTCAGTGTTGTAGGAAGTGTCCTGTATTTTACT
  AATTTTTGCCTTGATAAATTGGGGCAACCGCTTCTAAATGAAAACCCTCAGCTTTCCGAA
  GGATGGGAAATACCCAAGTACCATCAAGTCTTCAGCCACATTGTTTCTCTAGAAGGGCAA
  GAAATACAAGTAAAGGCAAAAAGGCCAAAGCCTCACTGTTTCAATTGTGGTTCTGAAGAA
  CACCAAATGAAAGATTGCCCAATGCCTCGGAATGCTGCTCGAATAAGTGAAAAGAGAAAA
  GAGTATATGGATGCCTGTGGAGAAGCAAACAATCAGAATTTCCAGCAGCGATACCACGCA
  GAAGAAGTAGAAGAAAGATTTGGAAGATTCAAGCCAGGAGTTATTAGTGAGGAACTTCAA
  GATGCACTAGGTGTGACAGACAAGAGTCTTCCACCTTTTATCTATCGGATGCGCCAGCTA
  GGGTACCCACCAGGGTGGCTCAAAGAGGTTGAATTGGAGAATTCGGGGCTTGCACTCTAT
  GATGGAAAAGATGGCACTGATGGGGAAACAGAAGTTGGAGAAATACAACAGAATAAAAGT
  GTCACTTACGATCTCTCAAAATTGGTCAACTATCCTGGTTTTAATATATCTACTCCCAGA
  GGAATTCCAGACGAATGGAGGATCTTTGGTTCCATACCAATGCAGGCATGTCAGCAGAAG
  GATGTGTTTGCCAATTACCTTACTTCTAACTTCCAAGCGCCAGGTGTGAAGTCTGGCAAC
  AAGAGGTCTTCATCTCACTCTAGCCCAGGTAGTCCAAAGAAGCAGAAGAATGAAAGCAAC
  TCAGCGGGATCTCCCGCCGACATGGAGCTCGATTCAGATATGGAGGTACCACATGGTTCT
  CAGAGCAGCGAAAGTTTTCAGTTTCAACCACCATTACCTCCTGACACTCCTCCACTCCCC
  CGGGGAACTCCTCCACCCGTCTTCACCCCTCCACTCCCAAAGGGCACCCCGCCGCTGACT
  CCCAGTGACTCACCCCAGACCAGAACAGCATCTGGAGCTGTGGATGAGGACGCACTGACT
  CTAGAAGAACTTGAAGAACAGCAGAGGCGGATCTGGGCAGCTCTTGAGCAGGCCGAGAGC
  GTAAACAGCGACTCCGACGTTCCTGTGGACACACCTTTAACTGGCAATTCCGTTGCCTCA
  TCACCTTGTCCAAATGAGCTAGACCTCCCTGTCCCGGAGGGAAAAACATCTGAAAAGCAG
  ACGCTGGATGAGCCTGAGGTACCAGAGATTTTTACAAAGAAATCAGAAGCTGGACATGCC
  TCCAGTCCAGACTCTGAGGTGACATCACTTTGTCAGAAGGAAAAAGCAGAGTTGGCTCCG
  GTAAACACTGAAGGTGCCCTTCTTGATAATGGCAGTGTCGTACCAAACTGTGACATCAGC
  AATGGGGGCAGCCAGAAGCTCTTTCCTGCAGACACCAGTCCTTCAACGGCCACTAAAATT
  CATAGCCCTATACCTGACATGAGCAAATTTGCAACTGGAATCACGCCATTTGAATTTGAG
  AATATGGCAGAATCTACTGGAATGTACCTCAGGATAAGAAGCTTGTTAAAGAACTCACCC
  CGAAACCAGCAGAAAAACAAAAAGGCCTCTGAATAATGGCTTGACTTAGCACTGAGAGCT
  ATTTAATAACTTTGTTCCGTTAATTAGTACTAATTAAGTGGATAGATAGAATGGTTTTCC
  TGTTTGTCCCTCCCATGTTTAAAAATCTATCCAAGGTTCATGTTCCAAAGTCAAGCCTAT
  TTTAAAGAAAGACTGAGCTCACTAGTTCAGTATATTTTATTCTCACTGACAAAACTTGGG
  GGGAGATGTGAATATGACCTGGTTTAGAGAGGGTTTGTTAAGGTTTATACTATTTTTGGA
  TTGTGACTATCCGTCGAGAGTGATGGTTTTTATCTGTCTTTTGTACATTGTTTTCCCTTT
  CTACATTTTGCTAATTATCCTGTATATAAGTTTAATATATCACTTTTTAAAAGAAAAAAT
  TCTACCATTTTAAATTCATGTTTCAACTCCTACAACCAAATGAGAAAAATCAGGGATGAG
  CAGCTTTATCCCATTTGGGGTATTTTTGTAAGTGATTTACATGTGTCAATTTTAGTAATA
  CTTTTACTTTTTTGTAACTTCATCCTTCATATATGCTTGCTATACAGGTATGTTCATCTT
  TGTGTACAGAGGTTTAATAAATTAGTTTTCATATAAGAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017612.2 unedited
  GGGCTCTTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTC
  CGGAATTCCCGGGATCGCCTTCCAACCTTCTTCCCCAAGCCCTGGTGGCCGGCTCCGCCT
  CTTCTCGAATCTTTTCCACAGCCCAAAATGGCCGCAGAGGTGTATTTTGGCGATCTAGAG
  CTCTTCGAGCCGTTCGACCACCCAGAGGAGTCGATTCCGAAGCCCGTTCACACTCGCTTC
  AAGGACGACGACGGCGACGAGGAGGACGAAAATGGGGTCGGCGACGCGGAGCTACGGGAG
  CGGCTTCGGCAGTGCGAGGAGACCATCGAGCAGCTCCGCGCCGAGAATCAAGAACTTAAA
  CGAAAATTGAACATTCTGACTCGACCGAGTGGAATATTGGTGAACGATACTAAGTTAGAT
  GGACCTATATTACAGATTCTATTCATGAACAATGCTATTTCAAAGCAATATCATCAAGAA
  ATAGAGGAATTTGTATCAAATTTAGTAAAAAGATTTGAGGAACAGCAGAAAAATGATGTG
  GAAAAGACTTCCTTTAATCTTTTGCCCCAGCCATCCAGTATTGTGCTAGAGGAGGACCAC
  AAAGTGGAAGAGTCCTGTGCCATTAAAAACAACAAAGGAAGCTTTCAGTGTTGTAGGAAG
  TGTCCTGTATTTTACTAATTTTTGCCTTGATAAATTGGGGCAACCGCTTCTAAATGAAAA
  CCCTCAGCTTTCCGAAGATGGGAAATACCCAAGTACCATCAAGTCTTCAGCCACATTGTT
  TCTCTAGAGGCAGAAATACAAGTAAAGGCAAAAAGCCAAAGCCTCACTGTTTCATTGTGG
  TTCTGAGACACAATGAAAGATTGCCAATGCCTCGGATGCTGCTCGATATGAAAGAGAAAA
  GAGTTAATTGGATGCTTGGTGGAGAAGCAAACATC
• Restriction Sites: Please inquire
• ACCN: NM_017612
• ORF Size: 2124 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_017612.2, NP_060082.2
• RefSeq Size: 2874
• RefSeq ORF: 2124
• Locus ID: 55596
• Domains: PSP
• Gene Summary: This gene encodes a scaffold protein which serves as an assessory factor to the nuclear RNA exosome complex. The encoded protein forms a trimeric human nuclear exosome targeting (NEXT) complex, together with hMTR4 and the RNA-binding factor RBM7 which promotes the exosomal degradation of non-coding promoter-upstream transcripts, enhancer RNAs and 3'-extended products of histone- and small nuclear RNA transcription. This complex is also thought to recruit the exosome to degrade intronic RNAs via its interaction with both the exosome and the spliceosome. It contains both an N-terminal zinc-knuckle domain and a C-terminal proline-rich domain. [provided by RefSeq, Apr 2017]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.