NOB1 (NM_014062) Human Untagged Clone

CAT#: SC321941

NOB1 (untagged)-Human NIN1/RPN12 binding protein 1 homolog (S. cerevisiae) (NOB1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NOB1
• Synonyms: ART-4; MST158; MSTP158; NOB1P; PSMD8BP1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014062.1 CATGGCTCCAGTGGAGCACGTTGTGGCGGATGCTGGGGCTTTCCTGCGGCATGCGGCTCT
  GCAGGACATCGGGAAGAACATTTACACCATCCGGGAGGTGGTCACTGAGATTCGGGACAA
  GGCCACACGCAGGCGGCTCGCTGTCCTGCCCTACGAGCTGCGGTTCAAGGAGCCCTTACC
  GGAATACGTGCGGCTGGTGACTGAGTTTTCAAAGAAAACAGGAGACTACCCCAGCCTCTC
  TGCCACGGACATCCAAGTGCTTGCACTCACATACCAGTTGGAAGCAGAGTTTGTTGGGGT
  GTCTCACCTAAAACAAGAACCACAGAAGGTTAAGGTGAGCTCATCGATTCAGCACCCAGA
  AACACCTCTGCACATTTCTGGTTTCCATCTGCCCTACAAGCCTAAACCCCCACAAGAAAC
  AGAAAAAGGACACTCAGCTTGTGAGCCTGAGAACCTGGAATTTAGTTCCTTCATGTTCTG
  GAGAAACCCTTTGCCCAACATCGATCATGAACTGCAGGAGCTGCTGATTGACAGAGGTGA
  GGACGTTCCAAGTGAGGAGGAGGAGGAGGAAGAAAACGGGTTTGAAGACAGAAAAGATGA
  CAGCGATGACGACGGGGGTGGCTGGATAACCCCCAGTAACATCAAGCAGATCCAGCAGGA
  GCTGGAGCAGTGTGACGTCCCCGAGGACGTGCGGGTTGGCTGCCTGACCACAGACTTCGC
  CATGCAGAATGTTCTGCTGCAGATGGGGCTGCACGTGCTGGCGGTGAACGGCATGCTGAT
  TCGTGAGGCCCGGAGCTACATCTTGCGCTGCCATGGCTGTTTCAAGACAACGTCTGACAT
  GAGCCGAGTGTTCTGCTCACACTGTGGGAACAAGACCCTGAAGAAAGTGTCCGTGACCGT
  CAGCGACGACGGCACCCTGCACATGCACTTCTCCCGCAACCCCAAGGTGCTGAACCCCCG
  CGGCCTCCGGTACTCGCTTCCCACTCCCAAAGGGGGCAAATACGCCATCAACCCCCATCT
  CACCGAGGATCAGCGCTTCCCTCAGCTGCGACTCTCCCAAAAGGCCAGGCAGAAAACCAA
  CGTGTTCGCCCCTGACTACATCGCCGGGGTGTCACCCTTTGTCGAGAATGACATCTCCAG
  CCGCTCAGCTACCCTGCAGGTCCGGGACAGCACCTTGGGAGCTGGGCGGAGACGCTTAAA
  TCCCAACGCTTCCAGAAAGAAGTTTGTGAAGAAAAGGTGAAGAGCGAGTTCCCGCAGGCA
  AATTGGATGGGCGTCTGGCCGCCGTGGAGTTCCGGTGACCCATTTCCCCAGCCGTGTCGT
  CTCCAGGACCACCCGATGGAAATAACAGGCGGGCTTCACGGTGCGGCTCTGTCCGCCCAT
  GCCCCGCTGGGTCTGCAGGGAACTGGACTGTCCCATGGCCTGTGAGCACCGGAGCGCCTG
  GCTGCCTGCCAAGGAAGTGCAATTGCATAAAAACAGAAAGAACAACGCCCTGGAGCCAAT
  CTTCAAGAAAGGAATTTCCAAAGGATAATATTTTTCTAATAAATGCGGCTGCAACCTCCT
  GTGCATTTAATTAAATAGGCCAAATTTTTGCTGCTTAGGTCATCTCAAGGCTGATACTTG
  AGCTGTGTGCCCAGAGATCATGCATTTAGATTTATATTTTTGCCAGAAAATACAAGGTTA
  TAATAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014062.1 unedited
  GGCCTTTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATATCGTCGACCCACGCGTCCGCATGGCTCCAGTGGAGCACGTTGTGGC
  GGATGCTGGGGCTTTCCTGCGGCATGCGGCTCTGCAGGACATCGGGAAGAACATTTACAC
  CATCCGGGAGGTGGTCACTGAGATTCGGGACAAGGCCACACGCAGGCGGCTCGCTGTCCT
  GCCCTACGAGCTGCGGTTCAAGGAGCCCTTACCGGAATACGTGCGGCTGGTGACTGAGTT
  TTCAAAGAAAACAGGAGACTACCCCAGCCTCTCTGCCACGGACATCCAAGTGCTTGCACT
  CACATACCAGTTGGAAGCAGAGTTTGTTGGGGTGTCTCACCTAAAACAAGAACCACAGAA
  GGTTAAGGTGAGCTCATCGATTCAGCACCCAGAAACACCTCTGCACATTTCTGGTTTCCA
  TCTGCCCTACAAGCCTAAACCCCCACAAGAAACAGAAAAAGGACACTCAGCTTGTGAGCC
  TGAGAACCTGGAATTTAGTTCCTTCATGTTCTGGAGAAACCCTTTGCCCAACATCGATCA
  TGAACTGCAGAGCTGCTGATTGACAGAGGTGAGGACGTTCCAAGTGAGGAGGAGGAGGAG
  GAAGAAAACGGGTTTGAAGACAGAAAAGATGACAGCGATGACGACGGGGTGGCTGGATAA
  CCCCCAGTAACATCAAGCAGATCCAGCAGAGCTGGAGCAGTGTGACGTCCCCGAGGACGT
  GCGGTTGGCTGCCTGACCACAGACTTCGCCATGCAGAATGTCTGCTGCAGATGGGGCTGC
  ACGTGCTGGCGGTGACGGCATGCTGATTCGTGGAGGCCCGGAGCTACATCTGCGCTGCAT
  GGCTGTTCAAGACAACGTCTGAACTGAGCGAGTGTTCTGCTCACACTGTGGGAACAAAGA
  CCTGGAAAAAGTGTTCCGTGAACGTTAACGGAAGAACG
• Restriction Sites: Please inquire
• ACCN: NM_014062
• ORF Size: 1239 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014062.1, NP_054781.1
• RefSeq Size: 1733
• RefSeq ORF: 1239
• Locus ID: 28987
• Gene Summary: In yeast, over 200 protein and RNA cofactors are required for ribosome assembly, and these are generally conserved in eukaryotes. These factors orchestrate modification and cleavage of the initial 35S precursor rRNA transcript into the mature 18S, 5.8S, and 25S rRNAs, folding of the rRNA, and binding of ribosomal proteins and 5S RNA. Nob1 is involved in pre-rRNA processing. In a late cytoplasmic processing step, Nob1 cleaves a 20S rRNA intermediate at cleavage site D to produce the mature 18S rRNA (Lamanna and Karbstein, 2009 [PubMed 19706509]). [supplied by OMIM, Nov 2010]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.