hnRNP L (HNRNPL) (NM_001005335) Human Untagged Clone

CAT#: SC321967

HNRNPL (untagged)-Human heterogeneous nuclear ribonucleoprotein L (HNRNPL), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HNRNPL
• Synonyms: hnRNP-L; HNRPL; P/OKcl.14
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC321967 GCAGAGGCAGCAGCCGGACGAGCAGCGGAGGCGGTCGGGAGCGATGGTGAAGATGGCGGC
  GGCGGGCGGCGGAGGCGGCGGTGGCCGCTACTACGGCGGCGGCAGTGAGGGCGGCCGGGC
  CCCTAAGCGGCTCAAGACTGACAACGCCGGCGACCAGCACGGAGGCGGCGGCGGTGGCGG
  TGGAGGAGCCGGGGCGGCGGGCGGCGGCGGCGGTGGGGAGAACTACGATGACCCGCACAA
  AACCCCTGCCTCCCCAGTTGTCCACATCAGGGGCCTGATTGACGGTGTGGTGGAAGCAGA
  CCTTGTGGAGGCCTTGCAGGAGTTTGGACCCATCAGCTATGTGGTGGTAATGCCTAAAAA
  GAGACAAGCACTGGTGGAGTTTGAAGATGTGTTGGGGGCTTGCAACGCAGTGAACTACGC
  AGCCGACAACCAAATATACATTGCTGGTCACCCAGCTTTTGTCAACTACTCTACCAGCCA
  GAAGATCTCCCGCCCTGGGGACTCGGATGACTCCCGGAGCGTGAACAGTGTGCTTCTCTT
  TACCATCCTGAACCCCATTTATTCGATCACCACGGATGTTCTTTACACTATCTGTAATCC
  TTGTGGCCCTGTCCAGAGAATTGTCATTTTCAGGAAGAATGGAGTTCAGGCGATGGTGGA
  ATTTGACTCAGTTCAAAGTGCCCAGCGGGCCAAGGCCTCTCTCAATGGGGCTGATATCTA
  TTCTGGCTGTTGCACTCTGAAGATCGAATACGCAAAGCCTACACGCTTGAATGTGTTCAA
  GAATGATCAGGATACTTGGGACTACACAAACCCCAATCTCAGTGGACAAGGTGACCCTGG
  CAGCAACCCCAACAAACGCCAGAGGCAGCCCCCTCTCCTGGGAGATCACCCCGCAGAATA
  TGGAGGGCCCCACGGTGGGTACCACAGCCATTACCATGATGAGGGCTACGGGCCCCCCCC
  ACCTCACTACGAAGGGAGAAGGATGGGTCCACCAGTGGGGGGTCACCGTCGGGGCCCAAG
  TCGCTACGGCCCCCAGTATGGGCACCCCCCACCCCCTCCCCCACCACCCGAGTATGGCCC
  TCACGCCGACAGCCCTGTGCTCATGGTCTATGGCTTGGATCAATCTAAGATGAACTGTGA
  CCGAGTCTTCAATGTCTTCTGCTTATATGGCAATGTGGAGAAGGTGAAATTCATGAAAAG
  CAAGCCGGGGGCCGCCATGGTGGAGATGGCTGATGGCTACGCTGTAGACCGGGCCATTAC
  CCACCTCAACAACAACTTCATGTTTGGGCAGAAGCTGAATGTCTGTGTCTCCAAGCAGCC
  AGCCATCATGCCTGGTCAGTCATACGGGTTGGAAGACGGGTCTTGCAGTTACAAAGACTT
  CAGTGAATCCCGGAACAATCGGTTCTCCACCCCAGAGCAGGCAGCCAAGAACCGCATCCA
  GCACCCCAGCAACGTGCTGCACTTCTTCAACGCCCCGCTGGAGGTGACCGAGGAGAACTT
  CTTTGAGATCTGCGATGAGCTGGGAGTGAAGCGGCCATCTTCTGTGAAAGTATTCTCAGG
  CAAAAGTGAGCGCAGCTCCTCTGGACTGCTGGAGTGGGAATCCAAGAGCGATGCCCTGGA
  GACTCTGGGCTTCCTGAACCATTACCAGATGAAAAACCCAAATGGTCCATACCCTTACAC
  TCTGAAGTTGTGTTTCTCCACTGCTCAGCACGCCTCCTAATTAGGTGCCTAGGAAGAGTC
  CCATCTGAGCAGGAAGACATTTCTCTTTCCTTTATGCCATTTTTTGTTTTTGTTATTTGC
  AAAAGATCTTGTATTCCTTTTTTTTTTTTTTTTTAAATGCTAGGTTTGTAGAGGCTTACT
  TAACCTTAATGGAAACGCTGGAAATCTGCAGGGGGAGGGAGAGGGGAACTGTTATCTCCC
  AAGATTAACCTTCACTTTTAAAAAATTATTGTACATGTGATTTTTTTTTTTCCTGTTCAT
  ACATTTGTGCTGCCCATGTACTCTTGGCACATTTCAATAAAATTGTTTGGAAAATAAAAA
  AAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_001005335
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001005335.1, NP_001005335.1
• RefSeq Size: 1895 bp
• RefSeq ORF: 1371 bp
• Locus ID: 3191
• Cytogenetics: 19q13.2
• Gene Summary: 'Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. Heterogeneous nuclear ribonucleoprotein L is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. Heterogeneous nuclear ribonucleoprotein L is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) differs in the 5' UTR and coding region compared to variant 1. The resulting isoform (b) has a shorter N-terminus compared to isoform a.