Peroxiredoxin 2 (PRDX2) (NM_181738) Human Untagged Clone

CAT#: SC322002

PRDX2 (untagged)-Human peroxiredoxin 2 (PRDX2), nuclear gene encoding mitochondrial protein, transcript variant 3


  "NM_181738" in other vectors (6)

Reconstitution Protocol

USD 420.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PRDX2
Synonyms NKEFB; PRP; PRX2; PRXII; PTX1; TDPX1; TPX1; TSA
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for SC322002 CGCGGGTCCACGCGTGTGATCGTCCGTGCGTCTAGCCTTTGCCCACGCAGCTTTCAGTCA
TGGCCTCCGGTAACGCGCGCATCGGAAAGCCAGCCCCTGACTTCAAGGCCACAGCGGTGG
TTGATGGCGCCTTCAAAGAGGTGAAGCTGTCGGACTACAAAGGGAAGTACGTGGTCCTCT
TTTTCTACCCTCTGGACTTCACTTTTGTGTGCCCCACCGAGATCATCGCGTTCAGCAACC
GTGCAGAGGACTTCCGCAAGCTGGGCTGTGAAGTGCTGGGCGTCTCGGTGGACTCTCAGT
TCACCCACCTGGCTTGGTATGAGCAGGGGCCAAAGAGGGAGGTTGCAGCTAAGCTCACAC
CCTCAGGTCCTAGCAGTGTGGCTTCGTGGCCATTGCTCAACCTCTGGAACCTGCGTTTCC
CCATCGTGAAAATAATGGAAACATTGCCGCCCAAGTCTTTAAGGATGATGACAGTAATTA
GCATTTGACAACTAGTTGCCTGGTATATAGAGTTGCAGATGCAACTCAGATGCAACTCTA
TCTACTCTATGTACTTAGTTCCCAGGAGGGAGGCTGTGCTGCCCTATTTCATGAAGATGG
AAACTCCAGTTCACCGAAGTGAAGGGCTGTACCCCATGACACAGCTAGAGGAGGATGGGG
ACTCTTAACACAGGCTCTCTGCTGGGTGATGCTGCAAGTTACAAGTACATGTGAAGCCAC
TTAGCTGGAGCTGTGCCTCTCAAACTCAGTCTTCCCAGCCATGGGGATACAGTCCTTGCA
CCCAACCCAGGGTGGGGTGGGTGAGGCTCCCAGCGGCCTACTCTAAAGCCCCTTATCTCC
GGCCTCCAGTGCTTATCACATTGGGCCCACAGGGTGAGGACCCTGCTGTGCCAGGCATCC
TGAGGCCCCAACTCTGTCTCCCCTACTCCCAGGATCAACACCCCCCGGAAAGAGGGAGGC
TTGGGCCCCCTGAACATCCCCCTGCTTGCTGACGTGACCAGACGCTTGTCTGAGGATTAC
GGCGTGCTGAAAACAGATGAGGGCATTGCCTACAGGTACTGTGGGACCCTCAGCCCGGCT
CAGGGAGCGCCCTGCCCCCCATTCCTGTGATGCTGGGACCACTCCTGTACAATGTCTTCT
CTGCCCCCAGCCCTGTGGCTAGCAGCGGGTGGTTGGTAGTCCCTTCCTTGTCTCTGGCAG
TGGGAGCTATCAGCTCCTCACTGGGAACCCTGATGTCTTCAGGGGCCTCTTTATCATCGA
TGGCAAGGGTGTCCTTCGCCAGATCACTGTTAATGATTTGCCTGTGGGACGCTCCGTGGA
TGAGGCTCTGCGGCTGGTCCAGGCCTTCCAGTACACAGACGAGCATGGGGAAGTTTGTCC
CGCTGGCTGGAAGCCTGGCAGTGACACGATTAAGCCCAACGTGGATGACAGCAAGGAATA
TTTCTCCAAACACAATTAGGCTGGCTAACGGATAGTGAGCTTGTGCCCCTGCCTAGGTGC
CTGTGCTGGGTGTCCACCTGTGCCCCCACCTGGGTGCCCTATGCTGACCCAGGAAAGGCC
AGACCTGCCCCTCCAAACTCCACAGTATGGGACCCTGGAGGGCTAGGCCAAGGCCTTCTC
ATGCCTCCACCTAGAAGCTGAATAGTGACGCCCTCCCCCAAGCCCACCCAGCCGCACACA
GGCCTAGAGGTAACCAATAAAGTATTAGGGAAAGGTGAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_181738
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_181738.1, NP_859428.1
RefSeq Size 710 bp
RefSeq ORF 429 bp
Locus ID 7001
Cytogenetics 19p13.13
Protein Families Druggable Genome
Gene Summary 'This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]'
Transcript Variant: This variant (3) uses an alternative splice site, compared to variant 1, which results in a translational frameshift. The resulting protein (isoform c) has a distinct C-terminus and is shorter than isoform a.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.