Mortality Factor 4 like 2 (MORF4L2) (NM_012286) Human Untagged Clone

CAT#: SC322120

MORF4L2 (untagged)-Human mortality factor 4 like 2 (MORF4L2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MORF4L2
• Synonyms: MORFL2; MRGX
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322120 ACTATGGCGGTTGGAGGAACGGCAGTGATCACACGTCGGCTGCTGGGAAGATCTGGATTC
  TCGTTTCAGGTCACCATCAGAAAAGCTAAGTTTGCTGTATAGTGAGGATCAGGAGATCTG
  ATCCTGATTGCAGAACCTTCCCTGATTACAGAATCTTGGGATTGTTGAGAGGATTACATG
  TAAAGTACCAGGACAGTGCATGGCACATGTTGTATCTCCCACTTCACCCTTCTAGACCAT
  CCCAGAAGATCTATAAGATTTCATCTGGGAAATCACTAGGAGTTCTTGGAAGGGAAAGAA
  GGAAGATTGTTGGTTGGAATAAAAACAGGGTTGAATGAGTTCCAGAAAGCAGGGTTCTCA
  ACCTCGTGGACAGCAATCTGCAGAAGAAGAGAACTTCAAAAAACCAACTAGAAGCAACAT
  GCAGAGAAGTAAAATGAGAGGGGCCTCCTCAGGAAAGAAGACAGCTGGTCCACAGCAGAA
  AAATCTTGAACCAGCTCTCCCAGGAAGATGGGGTGGTCGCTCTGCAGAGAACCCCCCTTC
  AGGATCCGTGAGGAAGACCAGAAAGAACAAGCAGAAGACTCCTGGAAACGGAGATGGTGG
  CAGTACCAGCGAAGCACCTCAGCCCCCTCGGAAGAAAAGGGCCCGGGCAGACCCCACTGT
  TGAAAGTGAGGAGGCGTTTAAGAATAGAATGGAGGTTAAAGTGAAGATTCCTGAAGAATT
  AAAACCATGGCTTGTTGAGGACTGGGACTTAGTTACCAGGCAGAAGCAGCTGTTTCAACT
  CCCTGCCAAGAAAAATGTAGATGCAATTCTGGAGGAGTATGCAAATTGCAAGAAATCGCA
  GGGAAATGTTGATAATAAGGAATATGCGGTTAATGAAGTTGTGGCAGGAATAAAAGAATA
  TTTCAATGTGATGTTGGGCACTCAGCTGCTCTACAAATTTGAGAGGCCCCAGTATGCTGA
  AATCCTCTTGGCTCACCCTGATGCTCCAATGTCCCAGGTTTATGGAGCACCACACCTACT
  GAGATTATTTGTAAGAATTGGAGCAATGTTGGCCTATACGCCCCTTGATGAGAAAAGCCT
  TGCATTATTGTTGGGCTATTTGCATGATTTCCTAAAATATCTGGCAAAGAATTCTGCATC
  TCTCTTTACTGCCAGTGATTACAAAGTGGCTTCTGCTGAGTACCACCGCAAAGCCCTGTG
  AGCGTCTACAGACAGCTCACCATTTTTGTCCTGTATCTGTAAACACTTTTTGTTCTTAGT
  CTTTTTCTTGTAAAATTGATGTTCTTTAAAATCGTTAATGTATAACAGGGCTTATGTTTC
  AGTTTGTTTTCCGTTCTGTTTTAAACAGAAAATAAAAGGAGTGTAAGCTCCTTTTCTCAT
  TTCAAAGTTGCTACCAGTGTATGCAGTAATTAGAACAAAGAAGAAACATTCAGTAGAACA
  TTTTATTGCCTAGTTGACAACATTGCTTGAATGCTGGTGGTTCCTATCCCTTTGACACTA
  CACAATTTTCTAATATGTGTTAATGCTATGTGACAAAACGCCCTGATTCCTAGTGCCAAA
  GGTTCAACTTAATGTATATACCTGAAAACCCATGCATTTGTGCTCTTTTTTTTTTTTTAT
  GGTGCTTGAAGTAAAACAGCCCATCCTCTGCAAGTCCATCTATGTTGTTCTTAGGCATTC
  TATCTTTGCTCAAATTGTTGAAGGATGGTGATTTGTTTCATGGTTTTTGTATTTGAGTCT
  AATGCACGTTCTAACATGATAGAGGCAATGCATTATTGTGTAGCCACGGTTTTCTGGAAA
  AGTTGATATTTTAGGAATTGTATTTCAGATCTTAAATAAAATTTGTTTCTAAATTTCAAA
  GCAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322120 unedited
  GGACCTTTGTTATACGACTCCTATAGGGCGGCCGCATAACTTCGTATAGCATACATTATA
  CGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGCTCTAGCGAGGTGA
  CAGCGTAGAACCAGACTATGGCGGTTGGAGGAACGGCAGTGATCACACGTCGGCTGCTGG
  GAAGATCTGGATTCTCGTTTCAGGTCACCATCAGAAAAGCTAAGTTTGCTGTATAGTGAG
  GATCAGGAGATCTGATCCTGATTGCAGAACCTTCCCTGATTACAGAATCTTGGGATTGTT
  GAGAGGATTACATGTAAAGTACCAGGACAGTGCATGGCACATGTTGTATCTCCCACTTCA
  CCCTTCTAGACCATCCCAGAAGATCTATAAGATTTCATCTGGGAAATCACTAGGAGTTCT
  TGGAAGGGAAAGAAGGAAGATTGTTGGTTGGAATAAAAACAGGGTTGAATGAGTTCCAGA
  AAGCAGGGTTCTCAACCTCGTGGACAGCAATCTGCAGAAGAAGAGAACTTCAAAAAACCA
  ACTAGAAGCAACATGCAGAGAAGTAAAATGAGAGGGGCCTCCTCAGGAAAGAAGACAGCT
  GGTCCACAGCAGAAAAATCTTGAACCAGCTCTCCCAGGAAGATGGGGTGGTCGCTCTGCA
  GAGAACCCCCCTTCAGATCCGTGAGGAAGACCAGAAAGAACAAGCAGAAGACTCCTGGAA
  ACGGAGATGGTGGCAGTACCAGCGAAGCACCCTCAGCCCCCCTCGAAGAAAAGGGCCCGG
  GCAGACCCCACTGTTGAAAGTGAGAGGCGTTTAGAATAGAATGGAGTAAAGTGAAGATCT
  GAGATTAAAACCATGCTGTGAGACTGGGACTAGTTACAGCAGAAGCAGCTGTTTCAACTC
  CCTGCAAGAAAAAGA
• Restriction Sites: Please inquire
• ACCN: NM_012286
• ORF Size: 867 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_012286.1, NP_036418.1
• RefSeq Size: 1826
• RefSeq ORF: 867
• Locus ID: 9643
• Protein Families: Transcription Factors
• Gene Summary: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1.