EXOSC1 (NM_016046) Human Untagged Clone

CAT#: SC322121

EXOSC1 (untagged)-Human exosome component 1 (EXOSC1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EXOSC1
• Synonyms: CGI-108; CSL4; Csl4p; p13; SKI4; Ski4p
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322121 GGCAATCATGGCGCCACCTGTGAGATACTGCATCCCCGGCGAACGTCTGTGTAACTTGGA
  GGAGGGCAGCCCGGGCAGCGGCACCTACACCCGCCACGGCTACATCTTTTCGTCGCTTGC
  CGGCTGTCTGATGAAGAGCAGCGAGAATGGCGCGCTTCCAGTGGTGTCTGTAGTGAGAGA
  AACAGAGTCCCAGTTACTGCCAGATGTGGGAGCTATTGTAACCTGTAAGGTCTCTAGCAT
  CAATTCACGCTTTGCCAAAGTACACATCCTGTATGTGGGGTCCATGCCTCTTAAGAACTC
  TTTTCGAGGAACTATCCGCAAGGAAGATGTCCGAGCAACTGAAAAAGACAAGGTTGAAAT
  TTATAAGAGTTTCCGCCCAGGTGACATTGTCTTGGCCAAAGTGATCTCCTTAGGTGATGC
  ACAGTCCAACTACCTGCTAACCACCGCCGAGAACGAGCTGGGAGTGGTGGTAGCCCACAG
  TGAGTCAGGTATCCAGATGGTTCCCATCAGCTGGTGTGAGATGCAGTGCCCTAAGACCCA
  CACTAAAGAATTCCGGAAAGTAGCCCGAGTACAACCCGAATTCTTGCAGACCTAAGAAGC
  CACTTTTTACCCTATGGAAGGGGGTAAGCTGTTCCTGAGTATAACACCAAGATGCTGCTG
  TCTTTATTCAAACACCTGGCGTCGGCCAACAGCCACTTCCAGAAAAATCTTCCAGTTTAC
  GCTGTAGATGGAACATGTTTCTGTGAACCTATCAGTGGATTTCATTCTCTTGAGTAATAA
  ATCTTATCTTTTCAAGACAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322121 unedited
  GACGTTTGTATACGACTCCTATAGGGCGGCCGCACTAACTTCGTATAGCATACATTATAC
  GAAGTTATGGTATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGGGCAATCAT
  GGCGCCACCTGTGAGATACTGCATCCCCGGCGAACGTCTGTGTAACTTGGAGGAGGGCAG
  CCCGGGCAGCGGCACCTACACCCGCCACGGCTACATCTTTTCGTCGCTTGCCGGCTGTCT
  GATGAAGAGCAGCGAGAATGGCGCGCTTCCAGTGGTGTCTGTAGTGAGAGAAACAGAGTC
  CCAGTTACTGCCAGATGTGGGAGCTATTGTAACCTGTAAGGTCTCTAGCATCAATTCACG
  CTTTGCCAAAGTACACATCCTGTATGTGGGGTCCATGCCTCTTAAGAACTCTTTTCGAGG
  AACTATCCGCAAGGAAGATGTCCGAGCAACTGAAAAAGACAAGGTTGAAATTTATAAGAG
  TTTCCGCCCAGGTGACATTGTCTTGGCCAAAGTGATCTCCTTAGGTGATGCACAGTCCAA
  CTACCTGCTAACCACCGCCGAGAACGAGCTGGGAGTGGTGGTAGCCCACAGTGAGTCAGT
  ATCCAGATGGTTCCCATCAGCTGGTGTGAGATGCAGTGCCCTAAGACCCACACTAAAGAA
  TTCCGGAAAGTAGCCCGAGTACAACCCGAATTCTTGCAGACCTAAGAAGCCACTTTTTAC
  CCTATGGAAGGGGTAAGCTGTTCCTGAGTATACACCAAGATGCTGCTGTCTTTATTCAAA
  CACCTGCGTCGCCAACAGCCACTTCAGAAAAATCTCAGTTTACGCTGTAGATGAACATTG
  TTTCTTGTGAACCTATCATGATTTCATTCTTCTTGGAGTAATAAATCTTATCCTTCCAGA
  CTAAACAAACTCTCCACGCTGGATCGCCATAGCCTGATCCTCAGGGGCCCGTACGATATC
  AGCTTGGTCGAACC
• Restriction Sites: Please inquire
• ACCN: NM_016046
• ORF Size: 588 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_016046.3, NP_057130.1
• RefSeq Size: 1150
• RefSeq ORF: 588
• Locus ID: 51013
• Protein Pathways: RNA degradation
• Gene Summary: This gene encodes a core component of the exosome. The mammalian exosome is required for rapid degradation of AU rich element-containing RNAs but not for poly(A) shortening. The association of this protein with the exosome is mediated by protein-protein interactions with ribosomal RNA-processing protein 42 and ribosomal RNA-processing protein 46. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2016]
  Transcript Variant: This variant (1) encodes the longest isoform (a).