STAR (NM_000349) Human Untagged Clone

CAT#: SC322286

STAR (untagged)-Human steroidogenic acute regulatory protein (STAR), nuclear gene encoding mitochondrial protein

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STAR
• Synonyms: STARD1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322286 GGCAGCAGCAGCGGCGGCAGCAGCAGCGGCAGCGACCCCACCACTGCCACATTTGCCAGG
  AAACAATGCTGCTAGCGACATTCAAGCTGTGCGCTGGGAGCTCCTACAGACACATGCGCA
  ACATGAAGGGGCTGAGGCAACAGGCTGTGATGGCCATCAGCCAGGAGCTGAACCGGAGGG
  CCCTGGGGGGCCCCACCCCTAGCACGTGGATTAACCAGGTTCGGCGGCGGAGCTCTCTAC
  TCGGTTCTCGGCTGGAAGAGACTCTCTACAGTGACCAGGAGCTGGCCTATCTCCAGCAGG
  GGGAGGAGGCCATGCAGAAGGCCTTGGGCATCCTTAGCAACCAAGAGGGCTGGAAGAAGG
  AGAGTCAGCAGGACAATGGGGACAAAGTGATGAGTAAAGTGGTCCCAGATGTGGGCAAGG
  TGTTCCGGCTGGAGGTCGTGGTGGACCAGCCCATGGAGAGGCTCTATGAAGAGCTCGTGG
  AGCGCATGGAAGCAATGGGGGAGTGGAACCCCAATGTCAAGGAGATCAAGGTCCTGCAGA
  AGATCGGAAAAGATACATTCATTACTCACGAGCTGGCTGCCGAGGCAGCAGGAAACCTGG
  TGGGGCCCCGTGACTTTGTGAGCGTGCGCTGTGCCAAGCGCCGAGGCTCCACCTGTGTGC
  TGGCTGGCATGGCCACAGACTTCGGGAACATGCCTGAGCAGAAGGGTGTCATCAGGGCGG
  AGCACGGTCCCACTTGCATGGTGCTTCACCCGTTGGCTGGAAGTCCCTCTAAGACCAAAC
  TTACGTGGCTACTCAGCATCGACCTCAAGGGGTGGCTGCCCAAGAGCATCATCAACCAGG
  TCCTGTCCCAGACCCAGGTGGATTTTGCCAACCACCTGCGCAAGCGCCTGGAGTCCCACC
  CTGCCTCTGAAGCCAGGTGTTGAAGACCAGCCTGCTGTTCCCAACTGTGCCCAGCTGCAC
  TGGTACACACGCTCATCAGGAGAATCCCTACTGGAAGCCTGCAAGTCTAAGATCTCCATC
  TGGTGACAGTGGGATGGGTGGGGTTCGTGTTTAGAGTATGACACTAGGATTCAGATTGGT
  GAAAGTTTTTAGTACCAAGAAAACAGGGATGAGGCTCTTGGATTAAAAGGTAACTTCATT
  CACTGATTAGCTATGACATGAGGGTTCAGGCCCCTAAAATAATTGTAAAACTTTTTTTCT
  GGGCCCTTATGTACCCACCTAAAACCATCTTTAAAATGCTAGTGGCTGATATGGGTGTGG
  GGGATGCTAACCACAGGGCCTGAGAAGTCTTGCTTTATGGGCTCAAGAATGCCATGCGCT
  GGCAGTACATGTGCACAAAGCAGAATCTCAGAGGGTCTCCTGCAGCCCTCTGCTCCTCCC
  GGCCGCTGCACAGCAACACCACAGAACAAGCAGCACCCCACAGTGGGTGCCTTCCAGAAA
  TATAGTCCAAGCTTTCTCTGTGGAAAAAGACAAAACTCATTAGTAGACATGTTTCCCTAT
  TGCTTTCATAGGCACCAGTCAGAATAAAGAATCATAATTCACACAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_000349
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000349.2, NP_000340.2
• RefSeq Size: 2695 bp
• RefSeq ORF: 858 bp
• Locus ID: 6770
• Cytogenetics: 8p11.23
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene plays a key role in the acute regulation of steroid hormone synthesis by enhancing the conversion of cholesterol into pregnenolone. This protein permits the cleavage of cholesterol into pregnenolone by mediating the transport of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane. Mutations in this gene are a cause of congenital lipoid adrenal hyperplasia (CLAH), also called lipoid CAH. A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jul 2008]