RAB3IP (NM_001024647) Human Untagged Clone

CAT#: SC322302

RAB3IP (untagged)-Human RAB3A interacting protein (rabin3) (RAB3IP), transcript variant A

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RAB3IP
• Synonyms: RABIN3; RABIN8
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322302 CTAAGCAAGCCTGGGCAATGGCGGGCGTCCCTCCCCCAGCCTCGTTGCCGCCTTGCAGTT
  TGATCTCAGACTGCTGTGCTAGCAATCAGCGAGATTCCGTGGGCGTAGGACCCTCTGAGC
  CAGGTGTGGGATATAGTCTCGTGGTGCGCCGTTTCTTAAGCCGGTCTGAAAAGCGCAATA
  TTCGGATGGGAGTGACCCGATTTTCCAGGAACTGAAGTTAAAAGATGAAGAATGTGAGAG
  GCTTTCAAAAGTGCGAGATCAACTTGGACAGGAATTGGAAGAACTCACAGCTAGTCTATT
  TGAGGAAGCTCATAAAATGGTGAGAGAAGCAAATATCAAGCAGGCAACAGCAGAAAAACA
  GCTAAAAGAAGCACAAGGAAAAATTGATGTACTTCAAGCTGAAGTAGCTGCATTGAAGAC
  ACTTGTATTGTCCAGTTCTCCAACATCACCTACGCAGGAGCCTTTGCCAGGTGGAAAGAC
  ACCTTTTAAAAAGGGGCATACAAGAAATAAAAGCACAAGCAGTGCTATGAGTGGCAGTCA
  TCAGGACCTCAGTGTGATACAGCCAATTGTAAAAGACTGCAAAGAGGCTGACTTATCCTT
  GTATAATGAATTCCGATTGTGGAAGGATGAGCCCACAATGGACAGGACGTGTCCTTTCTT
  AGACAAAATCTACCAGGAAGATATCTTTCCATGTTTAACATTCTCAAAAAGTGAGTTGGC
  TTCAGCTGTTCTGGAGGCTGTGGAAAACAATACTCTAAGCATTGAACCAGTGGGATTACA
  ACCTATCCGGTTTGTGAAAGCTTCTGCAGTTGAATGCGGAGGACCAAAAAAATGTGCTCT
  CACTGGCCAGAGTAAGTCCTGTAAACACAGAATTAAATTAGGGGACTCAAGCAACTATTA
  TTATATTTCTCCTTTTTGCAGATACAGGATCACTTCTGTATGTAACTTTTTTACATACAT
  TCGATACATTCAGCAGGGACTCGTGAAACAGCAGGATGTTGATCAGATGTTTTGGGAGGT
  TATGCAGTTGAGAAAAGAGATGTCATTGGCAAAGCTGGGTTATTTCAAAGAGGAACTCTG
  ATGCTCTGCGTGGGACCATGCCTGAACTCCCCGAATAACTGAAAAATGGCTGAATATTTT
  TATGGTTACTTGATATTTATTTCCAAGGAGTGAGCCTAAGACTTTTTTCCCCTTTTGCAA
  ATTGCTCTAAGAAGTACCATGATTTCTTTTAAACTGATCTATGCTGTGTTTGCTTATTCT
  TTAGTTGAACACACTATGAAGAATTCCAGGTGTACTAGTGAATGTAATTTATAGTTGCCA
  AAAAAAAAAAAAACCTGAAATAAATAAATGTTAGATTGAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322302 unedited
  TACCATTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATATCGTCGACCCACGCGTCCGCTAAGCAAGCCTGGGCAATGGCGGGCG
  TCCCTCCCCCAGCCTCGTTGCCGCCTTGCAGTTTGATCTCAGACTGCTGTGCTAGCAATC
  AGCGAGATTCCGTGGGCGTAGGACCCTCTGAGCCAGGTGTGGGATATAGTCTCGTGGTGC
  GCCGTTTCTTAAGCCGGTCTGAAAAGCGCAATATTCGGATGGGAGTGACCCGATTTTCCA
  GGAACTGAAGTTAAAAGATGAAGAATGTGAGAGGCTTTCAAAAGTGCGAGATCAACTTGG
  ACAGGAATTGGAAGAACTCACAGCTAGTCTATTTGAGGAAGCTCATAAAATGGTGAGAGA
  AGCAAATATCAAGCAGGCAACAGCAGAAAAACAGCTAAAAGAAGCACAAGGAAAAATTGA
  TGTACTTCAAGCTGAAGTAGCTGCATTGAAGACACTTGTATTGTCCAGTTCTCCAACATC
  ACCTACGCAGGAGCCTTTGCCAGGTGGAAAGACACCTTTTAAAAAGGGGCATACAAGAAA
  TAAAAGCACAAGCAGTGCTATGAGTGGCAGTCATCACGACCTCAGTGTGATACAGCCAAT
  TGTAAAAGACTGCAAAGAGGCTGACTTATCCTTGTATAATGAATTTCCGATTGTGGGAAG
  GATGAGCCCCACAATGGACAGGACGTGTCCCTTTTCTTAGAACAAAATCTACCAGAGATA
  TCTTTTCCATGTTTAACATTCTCAAAAAGTGAGTTGGCTTCAGCTGTTTCTGAGCTGTGG
  AAAAACATACTCTAGCATTGGACAAGTTGGGATAACACTATCCGTTGTGAAGGCTCTGCA
  GTGGAATGCGAGACGAAAAATGTGCTCAACTTGCCAGAGATAAGTCCC
• Restriction Sites: Please inquire
• ACCN: NM_001024647
• ORF Size: 765 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001024647.2, NP_001019818.1
• RefSeq Size: 8839
• RefSeq ORF: 765
• Locus ID: 117177
• Gene Summary: Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Mediates the release of GDP from RAB8A and RAB8B but not from RAB3A or RAB5. Modulates actin organization and promotes polarized transport of RAB8A-specific vesicles to the cell surface. Together with RAB11A, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (A) has multiple differences, which result in a distinct 5' UTR and cause translation initiation at a downstream start codon, compared to variant alpha 2. The resulting isoform (A) has a shorter N-terminus, compared to isoform alpha 2. Variants A and B encode the same isoform A. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.