PGEA1 (CBY1) (NM_001002880) Human Untagged Clone

CAT#: SC322372

CBY1 (untagged)-Human chibby homolog 1 (Drosophila) (CBY1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CBY1
• Synonyms: arb1; C22orf2; CBY; Chibby1; HS508I15A; PGEA1; PIGEA-14; PIGEA14
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322372 CAAGGTAACTCTGGGCTACAGAGTCCTTGCTGGGGGTTCGGGGAGCGCTTGGACCCCGGC
  TTCTGGGACGCGTCAGGAGAAGGGAGCACTGGCTTTGCTTTCATCAGGCCAAAGATGCCT
  TTCTTTGGGAATACGTTCAGTCCGAAGAAGACACCTCCTCGGAAGTCGGCATCTCTCTCC
  AACCTGCATTCTTTGGATCGATCAACCCGGGAGGTGGAGCTGGGCTTGGAATACGGATCC
  CCGACTATGAACCTGGCAGGGCAAAGCCTGAAGTTTGAAAATGGCCAGTGGATAGCAGAG
  ACAGGGGTTAGTGGCGGTGTGGACCGGAGGGAGGTTCAGCGCCTTCGCAGGCGGAACCAG
  CAGTTGGAGGAAGAGAACAATCTCTTGCGGCTGAAAGTGGACATCTTATTAGACATGCTT
  TCAGAGTCCACTGCTGAATCCCACTTAATGGAGAAGGAACTGGATGAACTGAGGATCAGC
  CGGAAGAGAAAATGAAGACCCCAGAGACATTTATTGGGGAGTAGGATGTGGCTGAGTGCT
  TTTTTTTTGGCCAGACTAGCGGATTCAGTCCTGGAAGAGAGTATCATATAATGAGACCCA
  CAGGCACTGGCACCCTTGGGTTGGCAATAGAAGGTGACATGGAATGGAGAAAACCAAGAT
  TCCAGATGGGGATAGTAACTAGAAGGTGCTTCAGATGCACTGCCTGCGGGTGCCAGTCTG
  AAAACCAGACCGCACAGAGGCCTGGGGCTGCTGATGAGCTTTTTGGTGCTCTCCACACAC
  AAGCTCGCAAACACACATGTCCCAGAATAGCTCTGTTGGGTTGTGTTGGGAGAAGCGGCT
  GGAGTTCATTCTCTCACCCCCTTATGTTGGTGTTTGGCGTGTGACAGCAGTTCTACAGAG
  CTCTGTGTTGGGGTCATGGATGAGCGGCTCTCTTGGCTCTTAAAGGCAGGCCTCTCTCTT
  CTTGCCTTTAAAGAATCCTCCTTCCTCACACCTGGCCTCCTCTGGCTTCAGCTTCTCAGC
  AGCAAGCACCAGCCTTCCACAACAACACTATATTTTTATGCTACTTTCCTGTTTGCACTA
  CTACTTTTTTATTAAACGATGTTAAATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_001002880
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001002880.1, NP_001002880.2
• RefSeq Size: 1287 bp
• RefSeq ORF: 510 bp
• Locus ID: 25776
• Cytogenetics: 22q13.1
• Protein Families: Transcription Factors
• Gene Summary: Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) contains an alternate exon compared to variant 1. The resulting isoform (b) is longer at the N-terminus compared to isoform a.