SIAT4A (ST3GAL1) (NM_173344) Human Untagged Clone

CAT#: SC322526

ST3GAL1 (untagged)-Human ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3GAL1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ST3GAL1
• Synonyms: 1; Gal-NAc6S; SIAT4A; SIATFL; ST3GalA; ST3GalA.1; ST3GalIA; ST3O
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322526 GGACACCCACACCCCTGTATTCTCCTCCGAACCCCTTCATGCCCAAATCCCGGAAACTCC
  AGCGTGTCTCCAGCCGTGTTGGTACCATTTTCAGATTTCATCTTCCTAAACTGGAAATGT
  CAATGAGAGGAAATTAACACCCCCAAGAGCTGCAGTGAGCAAATGCATTGAGCTTGGGTC
  AGGACAATTCCATTTGGGGACCAGAGATGGACGGTCACTCAGCCTATGGAGATGAAGAAA
  CTGAGGTTCAGAGAGGTTAAGAGACTCCACTGAGGTCACACAGCCGATGACAGACAACCT
  TCTGTGCCTTCATCAAGCTGGTTGTGTACCCACCATGTCCCTGGCGACAGGATGGGAAAG
  AAAAAGCCCTAATTAAGGATCGTCAGAAACCACAGTTGGAGGAGGACGGCAGAGACAGTT
  TCCCTCCCCGCTATACCAACACCCTTCCTTCGAGGTCCTCGCTCCTGAGGGACCCTGGAC
  TGTCACAGAGATTAATGACCCCTTATCTTCTTTGGATGTGAAAGGAAATCACTGGTTAAA
  GCTTGATCGAGAGACATTATCAGCTCTTTAAGGATTGCAGGAGAATAGGCTACTTTATTT
  TCTGAAAAGGAGGGAGTTCCTGCTACCCATCGTGGGAGGCCACCATCAGGACTGCGAAGA
  TGGTGACCCTGCGGAAGAGGACCCTGAAAGTGCTCACCTTCCTCGTGCTCTTCATCTTCC
  TCACCTCCTTCTTCCTGAACTACTCCCACACCATGGTGGCCACCACCTGGTTCCCCAAGC
  AGATGGTCCTGGAGCTCTCCGAGAACCTGAAGAGACTGATCAAGCACAGGCCTTGCACCT
  GCACCCACTGCATCGGGCAGCGCAAGCTCTCGGCCTGGTTCGATGAGAGGTTCAACCAGA
  CCATGCAGCCGCTGCTGACTGCCCAGAACGCGCTCTTGGAGGACGACACCTACCGATGGT
  GGCTGAGGCTCCAGCGGGAGAAGAAGCCCAATAACTTGAATGACACCATCAAGGAGCTGT
  TCAGAGTGGTGCCTGGGAATGTGGACCCTATGCTGGAGAAGAGGTCGGTGGGCTGCCGGC
  GCTGCGCCGTTGTGGGCAACTCGGGCAACCTGAGGGAGTCTTCTTATGGGCCTGAGATAG
  ACAGTCACGACTTTGTCCTCAGGATGAACAAGGCGCCCACGGCAGGGTTTGAAGCTGATG
  TTGGGACCAAGACCACCCACCATCTGGTGTACCCTGAGAGCTTCCGGGAGCTGGGAGATA
  ATGTCAGCATGATCCTGGTGCCCTTCAAGACCATCGACTTGGAGTGGGTGGTGAGCGCCA
  TCACCACGGGCACCATTTCCCACACCTACATCCCGGTTCCTGCAAAGATCAGAGTGAAAC
  AGGATAAGATCCTGATCTACCACCCAGCCTTCATCAAGTATGTCTTTGACAACTGGCTGC
  AAGGGCACGGGCGATACCCATCTACCGGCATCCTCTCGGTCATCTTCTCAATGCATGTCT
  GCGATGAGGTGGACTTGTACGGCTTCGGGGCAGACAGCAAAGGGAACTGGCACCACTACT
  GGGAGAACAACCCATCCGCGGGGGCTTTTCGCAAGACGGGGGTGCACGATGCAGACTTTG
  AGTCTAACGTGACGGCCACCTTGGCCTCCATCAATAAAATCCGGATCTTCAAGGGGAGAT
  GACGCAGTGAAGGGCTGAGGATGGACGCACTGTCACACCTCTGCATTTCCAGCCCCAGCA
  TCTTGCTGGAGCCGTTCCATCCCGGAGCTTGGAGGGGCAGCCTCAGGTGTGTGCCTGGGC
  ACCGCTCACAGCCTCTTGCACCCAGCCGTTGGCAGCATCTACTCAGCAAGGTCACTAAGC
  TCTGCCAGCGTGGCAGAGCATGTCTTGGAACCTGTCTTGAGTGGGGACAACGTCCCCCCA
  CTGCTGCCCTAGAGCTGGGGAGACGCTGGGAAAGGTTCAACCTCCACACACTAAAATCAT
  TTTGGCTCCTGGGGCAAGCTTGGGGAATGAATGTGGAAGATGCCTATATTCTGAGAGACA
  GGACAGTTTCCCAGGAAGATGGGCAGAGACTTGAGTGGCGATTACCTCCAGCACAGAGAC
  GTGCCAGGCGGTGTTGGCGCTCGGGGCGAGATGCTGCCCTTCTTTGCACGAAGCCTGGCC
  TCTTGCTTGGCGTGATAACCCTGTCATCTTCCCAAAGCTCATTTATGAGCCACCAGAGGC
  TCCTACCCCAAAGATTTTCACAGAAACTTGAGGCCAGGTGCCATGGCTCACACCTGTAAT
  CTGAACACTTTGGGAGGCCGAGGCGGGAGGATCACTTGAGCCCAGGAGTTCAAGACCAGC
  CTGGGCAACATAGTGAGACTCCTGTCTCTACAAAAATAAAAGATTTAAAAAAATTAGCCA
  GGCACGGTGGCACACACTTGTAGCCCCAGCTACTAGGGAGGCTGAGGAGGGAGGATCTCT
  TGTGCCTAGGAGTTCGAGGCTGCAGTGGGCTGTGATCACACCACTGCACTCCAGCCTGGG
  CAACAGAGTGAGACCCTGTCTCTGAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_173344
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_173344.1, NP_775479.1
• RefSeq Size: 2708 bp
• RefSeq ORF: 1023 bp
• Locus ID: 6482
• Cytogenetics: 8q24.22
• Protein Families: Secreted Protein, Transmembrane
• Protein Pathways: Glycosphingolipid biosynthesis - ganglio series, Glycosphingolipid biosynthesis - globo series, Keratan sulfate biosynthesis, Metabolic pathways, O-Glycan biosynthesis
• Gene Summary: 'The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.