KCNIP4 (NM_001035004) Human Untagged Clone

CAT#: SC322581

KCNIP4 (untagged)-Human Kv channel interacting protein 4 (KCNIP4), transcript variant 6


  "NM_001035004" in other vectors (4)

Reconstitution Protocol

USD 420.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol KCNIP4
Synonyms CALP; KCHIP4
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for SC322581 CCACGCGTCCGCCCACGCGTCCGCTCGAGTCTCGCTTCTGCACCCTGCGTCCCCAGACAT
GAATGTGAGGAGGGTGGAAAGCATTTCGGCTCAGCTGGAGGAGGCCAGCTCTACAGGCGG
TTTCCTGTACGCTCAGAACAGCACCAAGCGCAGCATTAAAGAGCGGCTCATGAAGCTCTT
GCCCTGCTCAGCTGCCAAAACGTCGTCTCCTGCTATTCAAAACAGCGTGGAAGATGAACT
GGAGATGGCCACCGTCAGGCATCGGCCCGAAGCCCTTGAGCTTCTGGAAGCCCAGAGCAA
ATTTACCAAGAAAGAGCTTCAGATCCTTTACAGAGGATTTAAGAACGAATGCCCCAGTGG
TGTTGTTAATGAAGAAACCTTCAAAGAGATTTACTCGCAGTTCTTTCCACAGGGAGACTC
TACAACATATGCACATTTTCTGTTCAATGCATTTGATACAGACCACAATGGAGCTGTGAG
TTTCGAGGATTTCATCAAAGGTCTTTCCATTTTGCTCCGGGGGACAGTACAAGAAAAACT
CAATTGGGCATTTAATCTGTATGACATAAATAAAGATGGCTACATCACTAAAGAGGAAAT
GCTTGATATAATGAAAGCAATATACGATATGATGGGTAAATGTACATATCCTGTCCTCAA
AGAAGATGCTCCCAGACAACACGTTGAAACATTTTTTCAGAAAATGGACAAAAATAAAGA
TGGGGTTGTTACCATAGATGAGTTCATTGAAAGCTGCCAAAAAGATGAAAACATAATGCG
CTCCATGCAGCTCTTTGAAAATGTGATTTAACTTGTCAAATAGATCCTGAATCCAACAGA
CAAATGTGAACTATTCTACCACCCTTAAAGTTGGAGCTACCACTTTTAGCATAGATTGCT
CAGCTTGACACTGAAGCATATTATGCAAACAAGCTTTGTTTTAATATAAAGCAATCCCCA
AAAGATTTGAGCTTTCAGTTATAAATTTGCATCCTTTTCATAATGCCACTGAGTTCAGGG
GATGGTCTAACTCATTTCATACTCTGTGAATATTCAAAAGTAATAGAATCTGGCATATAG
TTTTATTGGTTCCTTAGCCATGGGATTATTGAGGCTTTCACATATCAGTGATTTTAAAAT
ATCAGTGTTTTTTGCTACTCATTTGTATGTATTCAGTCCTAGGATTTTGAATGGTTTTCT
AATATAGTGACATCTGCATTTAATTTCCAGAAATTAAATTAATTTTCATGTTTGAATGCT
GTAATTCCATTTAAATTCCATTTATATACTTTAAGGAAACAAGATTACAACAATTAAAAA
AACACATAGTTCCAGTTTCTATGGCCTTCCCACCTTCTGTTAGAAATTAGTTTTATCTGG
CATTTTTAAACATTTAAAAATTATTAAACATTTAAAAATTAGTTTATTATCAGATATCAG
CATATGCCTAATAAAACTTATTTTAATAAGCAAAAAAAAAAAAAAAAAAAAAAA
Restriction Sites Please inquire     
ACCN NM_001035004
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001035004.1, NP_001030176.1
RefSeq Size 2345 bp
RefSeq ORF 567 bp
Locus ID 80333
Cytogenetics 4p15.31-p15.2
Protein Families Druggable Genome, Ion Channels: Other
Gene Summary This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (6) has an alternate exon which lacks an in-frame start codon, as compared to variant 1. Use of a downstream start codon results in an isoform (3) that has a shorter N-terminus, as compared to isoform 1. Variants 3 and 6 encode the same isoform (3).

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