KCNIP4 (NM_001035004) Human Untagged Clone

CAT#: SC322581

KCNIP4 (untagged)-Human Kv channel interacting protein 4 (KCNIP4), transcript variant 6

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNIP4
• Synonyms: CALP; KCHIP4
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322581 CCACGCGTCCGCCCACGCGTCCGCTCGAGTCTCGCTTCTGCACCCTGCGTCCCCAGACAT
  GAATGTGAGGAGGGTGGAAAGCATTTCGGCTCAGCTGGAGGAGGCCAGCTCTACAGGCGG
  TTTCCTGTACGCTCAGAACAGCACCAAGCGCAGCATTAAAGAGCGGCTCATGAAGCTCTT
  GCCCTGCTCAGCTGCCAAAACGTCGTCTCCTGCTATTCAAAACAGCGTGGAAGATGAACT
  GGAGATGGCCACCGTCAGGCATCGGCCCGAAGCCCTTGAGCTTCTGGAAGCCCAGAGCAA
  ATTTACCAAGAAAGAGCTTCAGATCCTTTACAGAGGATTTAAGAACGAATGCCCCAGTGG
  TGTTGTTAATGAAGAAACCTTCAAAGAGATTTACTCGCAGTTCTTTCCACAGGGAGACTC
  TACAACATATGCACATTTTCTGTTCAATGCATTTGATACAGACCACAATGGAGCTGTGAG
  TTTCGAGGATTTCATCAAAGGTCTTTCCATTTTGCTCCGGGGGACAGTACAAGAAAAACT
  CAATTGGGCATTTAATCTGTATGACATAAATAAAGATGGCTACATCACTAAAGAGGAAAT
  GCTTGATATAATGAAAGCAATATACGATATGATGGGTAAATGTACATATCCTGTCCTCAA
  AGAAGATGCTCCCAGACAACACGTTGAAACATTTTTTCAGAAAATGGACAAAAATAAAGA
  TGGGGTTGTTACCATAGATGAGTTCATTGAAAGCTGCCAAAAAGATGAAAACATAATGCG
  CTCCATGCAGCTCTTTGAAAATGTGATTTAACTTGTCAAATAGATCCTGAATCCAACAGA
  CAAATGTGAACTATTCTACCACCCTTAAAGTTGGAGCTACCACTTTTAGCATAGATTGCT
  CAGCTTGACACTGAAGCATATTATGCAAACAAGCTTTGTTTTAATATAAAGCAATCCCCA
  AAAGATTTGAGCTTTCAGTTATAAATTTGCATCCTTTTCATAATGCCACTGAGTTCAGGG
  GATGGTCTAACTCATTTCATACTCTGTGAATATTCAAAAGTAATAGAATCTGGCATATAG
  TTTTATTGGTTCCTTAGCCATGGGATTATTGAGGCTTTCACATATCAGTGATTTTAAAAT
  ATCAGTGTTTTTTGCTACTCATTTGTATGTATTCAGTCCTAGGATTTTGAATGGTTTTCT
  AATATAGTGACATCTGCATTTAATTTCCAGAAATTAAATTAATTTTCATGTTTGAATGCT
  GTAATTCCATTTAAATTCCATTTATATACTTTAAGGAAACAAGATTACAACAATTAAAAA
  AACACATAGTTCCAGTTTCTATGGCCTTCCCACCTTCTGTTAGAAATTAGTTTTATCTGG
  CATTTTTAAACATTTAAAAATTATTAAACATTTAAAAATTAGTTTATTATCAGATATCAG
  CATATGCCTAATAAAACTTATTTTAATAAGCAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_001035004
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001035004.1, NP_001030176.1
• RefSeq Size: 2345 bp
• RefSeq ORF: 567 bp
• Locus ID: 80333
• Cytogenetics: 4p15.31-p15.2
• Protein Families: Druggable Genome, Ion Channels: Other
• Gene Summary: This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. This protein member also interacts with presenilin. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (6) has an alternate exon which lacks an in-frame start codon, as compared to variant 1. Use of a downstream start codon results in an isoform (3) that has a shorter N-terminus, as compared to isoform 1. Variants 3 and 6 encode the same isoform (3).