Calnexin (CANX) (NM_001024649) Human Untagged Clone

CAT#: SC322601

CANX (untagged)-Human calnexin (CANX), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CANX
• Synonyms: CNX; IP90; P90
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322601 GGCACGTGACGGTCGGGCCGCCTCCGCCTCTCTCTTTACTGCGGCGCGGGGCAAGATCAT
  GGAAGGGAAGTGGTTGCTGTGTATGTTACTGGTGCTTGGAACTGCTATTGTTGAGGCTCA
  TGATGGACATGATGATGATGTGATTGATATTGAGGATGACCTTGACGATGTCATTGAAGA
  GGTAGAAGACTCAAAACCAGATACCACTGCTCCTCCTTCATCTCCCAAGGTTACTTACAA
  AGCTCCAGTTCCAACAGGGGAAGTATATTTTGCTGATTCTTTTGACAGAGGAACTCTGTC
  AGGGTGGATTTTATCCAAAGCCAAGAAAGACGATACCGATGATGAAATTGCCAAATATGA
  TGGAAAGTGGGAGGTAGAGGAAATGAAGGAGTCAAAGCTTCCAGGTGATAAAGGACTTGT
  GTTGATGTCTCGGGCCAAGCATCATGCCATCTCTGCTAAACTGAACAAGCCCTTCCTGTT
  TGACACCAAGCCTCTCATTGTTCAGTATGAGGTTAATTTCCAAAATGGAATAGAATGTGG
  TGGTGCCTATGTGAAACTGCTTTCTAAAACACCAGAACTCAACCTGGATCAGTTCCATGA
  CAAGACCCCTTATACGATTATGTTTGGTCCAGATAAATGTGGAGAGGACTATAAACTGCA
  CTTCATCTTCCGACACAAAAACCCCAAAACGGGTATCTATGAAGAAAAACATGCTAAGAG
  GCCAGATGCAGATCTGAAGACCTATTTTACTGATAAGAAAACACATCTTTACACACTAAT
  CTTGAATCCAGATAATAGTTTTGAAATACTGGTTGACCAATCTGTGGTGAATAGTGGAAA
  TCTGCTCAATGACATGACTCCTCCTGTAAATCCTTCACGTGAAATTGAGGACCCAGAAGA
  CCGGAAGCCCGAGGATTGGGATGAAAGACCAAAAATCCCAGATCCAGAAGCTGTCAAGCC
  AGATGACTGGGATGAAGATGCCCCTGCTAAGATTCCAGATGAAGAGGCCACAAAACCCGA
  AGGCTGGTTAGATGATGAGCCTGAGTACGTACCTGATCCAGACGCAGAGAAACCTGAGGA
  TTGGGATGAAGACATGGATGGAGAATGGGAGGCTCCTCAGATTGCCAACCCTAGATGTGA
  GTCAGCTCCTGGATGTGGTGTCTGGCAGCGACCTGTGATTGACAACCCCAATTATAAAGG
  CAAATGGAAGCCTCCTATGATTGACAATCCCAGTTACCAGGGAATCTGGAAACCCAGGAA
  AATACCAAATCCAGATTTCTTTGAAGATCTGGAACCTTTCAGAATGACTCCTTTTAGTGC
  TATTGGTTTGGAGCTGTGGTCCATGACCTCTGACATTTTTTTTGACAACTTTATCATTTG
  TGCTGATCGAAGAATAGTTGATGATTGGGCCAATGATGGATGGGGCCTGAAGAAAGCTGC
  TGATGGGGCTGCTGAGCCAGGCGTTGTGGGGCAGATGATCGAGGCAGCTGAAGAGCGCCC
  GTGGCTGTGGGTAGTCTATATTCTAACTGTAGCCCTTCCTGTGTTCCTGGTTATCCTCTT
  CTGCTGTTCTGGAAAGAAACAGACCAGTGGTATGGAGTATAAGAAAACTGATGCACCTCA
  ACCGGATGTGAAGGAAGAGGAAGAAGAGAAGGAAGAGGAAAAGGACAAGGGAGATGAGGA
  GGAGGAAGGAGAAGAGAAACTTGAAGAGAAACAGAAAAGTGATGCTGAAGAAGATGGTGG
  CACTGTCAGTCAAGAGGAGGAAGACAGAAAACCTAAAGCAGAGGAGGATGAAATTTTGAA
  CAGATCACCAAGAAACAGAAAGCCACGAAGAGAGTGAAACAATCTTAAGAGCTTGATCTG
  TGATTTCTTCTCCCTCCTCCCCTGCAAGAGTGGTCCTAGGAGAGGACCTGGCACACCTTA
  GGTTGACATTCAGAAAACTTCAAGACATCACCATCAGCAGGCTCCAGTTGAACACTAGTC
  TGTGTAACTTTAAACATCTAGCAGTAAATACTTGCAGTTGTGATATAAAGGACCCTGTTT
  CTGTAGAAAAGAAAACATTTAACATAATGGTTGTGAAATGTAACATGAAGCAAACTAACT
  TTTTTTTTTTAACATCTTTGTTTTTAAAATAGAATGATAGAACTTTGCCAGTCTTTAAGA
  TCTTGGCTTAATTTAATGTATTAATCTGTTTGTGCAAACATAATACCACCATTTAAAAAT
  GTTAGGGAGATGAGTTGCAGTTTTTATAATAGATTTTTTTTAAAGTTTGGTATTGTAAAA
  CATTCACACCTCTGTCCCTCAAAATTGATAATTACGTTTAAAGTGCAGTCATTTGTGGTT
  AGAATCTTGTTTTGTTTGCTTCCATTATTGAGTTCCTCCTAAGGAAATTGAGGAGAGGGA
  CTGAATAGAAGCCCAAATTCATATAAAAGTTGCGTTTAAGTTGTATTAAAAATAGATATA
  TAAGAAAAAATTCTTTCACTTGATGTTTGTTAGACCAGAAAGTGTGTGTGTTCTGTAGCT
  CAGTTCCCAGACAGCTTTTTAGGTAGTGGAGGAGGTGGCTTCATGTGGCACTTGGGCATT
  TATATTCCACTTGGGAGGGTCAGGCTGTGGCCTTCTGGAGCAGGTGGCTTGTTAAGGAAT
  GCTAGCAGGGCATGGCACGTGAGCTCCGGAATAGATGTCTTCATCACTTCTTCCACTGTG
  TGTTGACACTGTTTTCCTTACCTATTTCCTCAGATCCCCAGCTTTCTCCTCTGCTATGCA
  TTTTCTTCACAGTGCAGCTTGCAGTCTGTTGCTGAAAATGATTATAAGCCCTGCATAATG
  TTAAGCTTTATTGTGATTACGTGTATGTTTCTTCTTTCTTTTAAGCAGACCCATACCTTT
  CCAGGGTCAAAGTACAGAATAGAATACATTGATACAAAGTACAGAAAAATACTTTGATTT
  TTATCCATTTCTTTTACTCTGTGTAAAGACTTGAGAAGTCTAATTCACAGGCAAACCAAT
  ACAGAATTGACTGCAGTTGAACAGACTAGAAGTATTTGTGGGAGGAGTGACATGAAGCAT
  GAGTTATCTGATTTTTTTTGTAGCTGCTATATATTTTAAGCCTTCATTTGCAATTCATGT
  AACAGTTGTGTCATAAATTACACAATAAAGCAGTCCTGTTCAAATTTTTTTTTAACGTGG
  CTTGTAGAATTTTTAAAAAAGTGATCTTAGGTTTGTTTTTTCATGCGGGATGCAGATGGG
  TGCTATCAGAGCCTCTCCCACACCACTATAGTGTAATAATGTTATTATTACTCTACACTG
  AAACGTATTCAGAGTTAGATATTATTTTAGCTTCAGTTGTTCTTTAGAGGCTTTCAAATG
  TACCGATGATACTGTTTCTTGCACTGAATATATAAACACTCCACAGTGTTTATATTGGGA
  AGATATTGGGAAGGAAATATATTTGTAAAAGATGAAGGCTGTATCTATTTTTTTTTCTTT
  TTAAAGTTTGTTCACTTAAATTCTTTTGAGGATGGGATGTATTTTTCTTGCTGTTCAGTG
  CTTTTTCCTTTTCATCTGTTGTTCTGTGGTCACAGTGACCTTAGCTACATAGCAGACTTT
  CCCAAATGTATTGATTACAAATAAACAGTTGTTACTTAGCAAGACCTGAAAATATGTCTG
  CAGGTTTCTCCTTGAAGCAAATGTGTGGGATCATTGCATTTCCAGAAATCTGCCTCCTTC
  ACCCTCCGTTGACAGTATATGTCATGCCTCACTTTCTTCTAGCTGAGCTTTAAATCATTA
  GAGCTTAAATTGTCAGATCGTTCATTGCCTTTCCAGGGTTATTTAGTAAAGTTTGTTGAA
  AACAAAAACGCCTTTTCTTGGTTCTTTTTTCAGTTATTTTGAAGGTCCAGCATCCTGATT
  AAATGTCTGACACATTAATGAATGACCAGCAGCAGCTTTCAGCTCTTAAAAAGACACTTA
  TATTTTGATTTTACATGCTGGTTACCTGTTCCATTGTTGTCAAATGCCCACTCTCCATCA
  GATGTGTTCCTCCATTTTTTTATCCACAAAGTACTCCTCACTTTTCAATTTGTCATGTTA
  CTAAATGGTGTTACATTAAAGCCCTGTGTTAAGTGTCAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_001024649
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001024649.1, NP_001019820.1
• RefSeq Size: 4900 bp
• RefSeq ORF: 1779 bp
• Locus ID: 821
• Cytogenetics: 5q35.3
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Antigen processing and presentation
• Gene Summary: 'This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2018]'
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.