ZNF384 (NM_001039920) Human Untagged Clone

CAT#: SC322692

ZNF384 (untagged)-Human zinc finger protein 384 (ZNF384), transcript variant 6

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZNF384
• Synonyms: CAGH1; CAGH1A; CIZ; ERDA2; NMP4; NP; TNRC1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322692 AGCTCTTCTCTGAGCCTGTTGGGGGGAGGGAGGGGGGCGTGGAGGAACTGGGGTTCGCGG
  GAGCACGAGCTGCAGCACCACTTCCGGAAAGTTCAGGAGCCCTGGAAAGGAGAAGGAATA
  AGACGGCAGGAGGAAGAGAGAGAGAGGGTAGAATGGAAGAATCTCACTTCAATTCTAACC
  CGTACTTCTGGCCTTCTATCCCCACAGTCTCAGGTCAGATCGAGAACACAATGTTCATCA
  ACAAGATGAAGGATCAGCTGTTGCCAGAGAAGGGCTGTGGTCTGGCCCCACCTCACTACC
  CCACCTTGCTGACAGTGCCTGCCTCAGTGTCCCTGCCCTCAGGCATCAGTATGGACACAG
  AGTCCAAGTCAGACCAGCTGACCCCACACAGCCAAGCGTCCGTTACCCAGAATATCACGG
  TGGTCCCTGTGCCGTCTACAGGACTGATGACTGCTGCCCTGCAGGTTGTCCCTGACCTCT
  CCAAGAAGGTAGCATCGACCCTAACCGAGGAAGGAGGCGGAGGTGGTGGTGGAGGTGGCA
  GTGTGGCTCCTAAGCCACCCCGGGGCCGGAAGAAGAAGCGGATGCTGGAATCAGGGCTGC
  CCGAGATGAATGACCCTTATGTCCTCTCCCCTGAGGATGATGATGACCATCAGAAAGACG
  GCAAGACCTACAGGTGCCGGATGTGCTCACTGACATTCTACTCCAAGTCGGAGATGCAGA
  TCCACTCCAAGTCACACACCGAGACCAAGCCCCACAAGTGCCCACATTGCTCCAAGACCT
  TCGCCAACAGCTCCTACCTGGCCCAGCACATCCGTATACACTCAGGGGCTAAGCCCTACA
  GTTGTAACTTCTGTGAGAAATCCTTCCGCCAGCTCTCCCACCTTCAGCAGCACACCCGAA
  TCCACACTGGTGATAGACCATACAAATGTGCACACCCAGGCTGTGAGAAAGCCTTCACAC
  AACTCTCCAATCTGCAGTCCCACAGACGGCAACACAACAAAGATAAACCCTTCAAGTGCC
  ACAACTGTCATCGGGCGTACACGGATGCAGCCTCACTAGAGGTGCACCTGTCTACGCACA
  CAGTGAAGCATGCCAAGGTGTACACCTGCACTATCTGCAGTCGGGCATACACATCAGAAA
  CATACCTTATGAAACATATGCGCAAACACAACCCGCCTGATCTTCAGCAACAGGTGCAGG
  CAGCAGCAGCAGCGGCAGCAGTGGCCCAGGCCCAGGCTCAAGCTCAAGCCCAGGCTCAGG
  CTCAGGCTCAAGCCCAGGCCCAGGCCCAGGCCTCCCAGGCATCACAGCAGCAGCAGCAGC
  AGCAGCAGCAGCAGCAGCAGCAGCAACAGCCACCACCACACTTCCAGTCTCCTGGGGCAG
  CCCCCCAGGGTGGGGGTGGTGGGGACAGCAATCCCAACCCTCCACCCCAGTGTTCCTTTG
  ACCTGACCCCGTATAAGACGGCGGAGCATCATAAGGACATCTGCCTCACTGTCACCACCA
  GCACCATCCAGGTGGAGCACCTGGCCAGCTCTTAGAGATCCGTGCTGCCACCCACTGGGA
  AGAGGAAGAAGTAGTCCTGGTGTCTTCTTTCTCCAACTCTTGGTGGGAAAAGTCCTTTTC
  TTCCTTGACAGGCCTTGGCTCCATCTCCTTGGGCCTCTGTCACGGCTTTCCTTCACAGGA
  TACCATCCTTTTTCTGAACTCTTCTTCAAAAGGAACATCAGCCCTCCTGATTGCAAAGGA
  ATACTGAGCTGATGGTGTCATCCAGCAGCCTCCCCTCCCAAGCAAAGCTTCTAAAACTGG
  GGGTCGGTGCTCAAGGGAAGGATTTGCTATGACCTCATAGAACCTTGTCCAGTGTGGCCA
  CTTACCCTATCCTTACCCTCCTTATCCTCAAAGTTTGGGCTGATGTAAGACTAGAGGCTG
  GCCCTCCCAGATAACAGAGAAAAGGGAGCCCCAAATGCAACCAGCCTCTTGTTCTATTCT
  TGCCTGCAAAAGAACAGAGGTTTCTCAAATGCCTCAGTCCCTGAGAGCCATTTCTTCCCC
  TACATCGTCTCACTTTGCTTCCTATTGACTGCTGGTAGAAGGAGATTTGGGGTAGGGGCT
  AGACCTCCTTTTATTTGAAGGGGGCAAGGGCTGAGATGTGGTCCCCAAGGGGCCAGAAAT
  TCCCAAGTTGGTCACAGGTGGCTTAGAAGTGTGTGTTATGGTTTTACGGATTTCCTTGAA
  GCCTCTCTCCTTCTCTGCCTACAAAGACCCTATACTCTCAGTCTCCCCAACCCACCCCCA
  AGGAGCTGTGGGAGGCTTTGTGTTATCTGTGAAACTCCAAAACAGGGGTGTTGCGGAGAA
  GGGAGAGTTCAAGGCAAACGCAAGGACTGGACTTAGCTCCCTAGGTGCCACAGTCAGATG
  CCGGACACGGATTTATATATAAATATATATATATAAATATATTATACTCACTCATCACGG
  CCATCTTTGTTGTAACCATTTCTGTGTTTATAAATGCATTATCTCTGAAAAAAAAAAAAA
  AAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322692 unedited
  GTCGCATTTTAGTATATTGTATACGACTCCTATAGGGCGGCCCGCGATCGCGGCGCGCCG
  GTACCGGTCCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGAGCTCTTCTCTGAGCC
  TGTTGGGGGGAGGGAGGGGGGCGTGGAGGAACTGGGGTTCGCGGGAGCACGAGCTGCAGC
  ACCACTTCCGGAAAGTTCAGGAGCCCTGGAAAGGAGAAGGAATAAGACGGCAGGAGGAAG
  AGAGAGAGAGGGTAGAATGGAAGAATCTCACTTCAATTCTAACCCGTACTTCTGGCCTTC
  TATCCCCACAGTCTCAGGTCAGATCGAGAACACAATGTTCATCAACAAGATGAAGGATCA
  GCTGTTGCCAGAGAAGGGCTGTGGTCTGGCCCCACCTCACTACCCCACCTTGCTGACAGT
  GCCTGCCTCAGTGTCCCTGCCCTCAGGCATCAGTATGGACACAGAGTCCAAGTCAGACCA
  GCTGACCCCACACAGCCAAGCGTCCGTTACCCAGAATATCACGGTGGTCCCTGTGCCGTC
  TACAGGACTGATGACTGCTGCCCTGCAGGTTGTCCCTGACCTCTCCAAGAAGGTAGCATC
  GACCCTAACCGAGAAGGAGGCGGAGGTGGTGGTGGAGGTGGCAGTGTGGCTCCTAAGCCA
  CCCCGGGGCCGGAAGAGAAGCGGATGCTGGGAATCAGGGCCTGCCCGAGATGAAATGACC
  CTTATGTCCTCTCCCCTGAGGATGATGATGACCCATCAAAAAGACGCAAGACCTACATGT
  GCCGGATTGTGCCTCACTGACATTCTACTCCAGTCCGAGATGCAGATCCACTCAGTCAAC
  ACACGGAGAACCAAGCCCACAAGTGGCACATTGCTCCAGACTTGCCAACGCTCTCTACTT
  GCAGACCATTCGTTATACACCTCTAAGGCCTTAAGG
• Restriction Sites: Please inquire
• ACCN: NM_001039920
• ORF Size: 1386 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001039920.1, NP_001035009.1
• RefSeq Size: 2824
• RefSeq ORF: 1386
• Locus ID: 171017
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]
  Transcript Variant: This variant (6) lacks two alternate in-frame exons and uses an alternate in-frame splice site in the central coding region, compared to variant 7, resulting in an isoform (c) that is shorter than isoform d.