sphingosine 1 phosphate phosphatase 1 (SGPP1) (NM_030791) Human Untagged Clone

CAT#: SC322734

SGPP1 (untagged)-Human sphingosine-1-phosphate phosphatase 1 (SGPP1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SGPP1
• Synonyms: SPP-1; SPPase1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322734 GCGCTGTGCCGGTTCCGCTGCCGCTGGCCAGGAGCGCGGGGACAGTTCGGGGCTGCGCCG
  GAGGCCGGCCCGCCTTCCCGGGGGTTCCGTTATCATGTCGCTGAGGCAGCGCCTGGCCCA
  GCTGGTTGGCCGTCTGCAGGACCCGCAGAAAGTGGCCCGTTTCCAGCGGCTGTGCGGGGT
  GGAAGCGCCGCCGCGCCGCTCAGCAGACCGGAGGGAGGATGAGAAAGCGGAGGCGCCTCT
  CGCCGGAGACCCTCGACTGCGAGGGCGGCAGCCAGGGGCGCCTGGAGGCCCCCAGCCTCC
  CGGGAGCGACCGCAATCAGTGCCCGGCCAAGCCGGACGGCGGCGGCGCCCCCAACGGCGT
  GCGGAACGGGCTGGCGGCCGAGCTGGGCCCGGCCTCGCCGCGGCGCGCGGGCGCTCTGCG
  CCGCAACTCGCTGACGGGCGAGGAGGGCCAGCTGGCCCGCGTGAGCAACTGGCCGCTCTA
  CTGCCTGTTCTGCTTCGGCACGGAGCTGGGCAACGAACTCTTCTACATCCTGTTCTTCCC
  CTTCTGGATCTGGAACCTGGACCCTCTGGTGGGCCGGAGGCTCGTGGTCATCTGGGTGCT
  GGTCATGTACCTGGGCCAGTGCACCAAGGACATCATCCGCTGGCCGAGGCCCGCCTCGCC
  GCCCGTGGTCAAGTTGGAGGTCTTCTACAACTCTGAGTACAGCATGCCCTCCACCCATGC
  CATGTCCGGCACCGCCATCCCCATTTCTATGGTCCTCCTCACCTATGGCCGCTGGCAGTA
  CCCTCTTATATATGGACTGATTCTTATTCCCTGCTGGTGTTCTCTAGTTTGCCTAAGTAG
  AATTTACATGGGAATGCACTCTATTCTGGATATTATTGCTGGATTCCTATATACCATTTT
  AATCTTAGCTGTCTTCTATCCATTTGTGGACCTGATTGACAACTTCAACCAAACTCACAA
  ATATGCTCCATTCATCATCATCGGGCTTCATTTAGCTTTGGGGATCTTTTCTTTCACTCT
  TGACACCTGGAGCACATCCCGAGGAGACACAGCCGAGATACTAGGAAGTGGTGCTGGAAT
  TGCATGTGGATCTCATGTTACTTATAACATGGGTCTAGTATTAGATCCTTCTCTAGATAC
  ATTACCTTTAGCTGGGCCCCCCATTACTGTGACTCTGTTTGGAAAAGCCATATTGCGGAT
  CCTCATAGGGATGGTATTTGTACTAATAATCAGAGATGTAATGAAAAAGATCACCATTCC
  TTTAGCCTGCAAAATCTTCAATATACCGTGTGATGATATTCGAAAAGCAAGACAGCACAT
  GGAAGTTGAACTTCCTTATCGGTATATTACCTATGGAATGGTTGGTTTCTCCATCACATT
  TTTTGTTCCTTACATATTTTTCTTTATTGGTATCTCTTGATGGAGAAGTATTGTTTATGA
  TAAGAAAGGAGGGTATCAGTTACTGATACCCAAAAATATATTCCAGGTAAAGCCAGGTCA
  GAATTAGGCTTTTGCAGGAATTTAACTTAAATAATTATTTAAGTAAATTCATAAGAGTCA
  GTGCATTTTATCATTGCACATCCAGATACTGTTTTAGGTGAGCTGAGCTATTTCGTTACT
  GAGAAAATGATAAGTATCCATTTAGAATGTTCATGTAATGTTTGGAGAGTTTTGTATTAT
  GGATTCAACTTATATATAATATATATAAGGTACATAATATGCAATTATGTATCTGATATA
  TATTATATATAAAATAATATACCTAAGTGTTTTTTTAAACTATGGGAGTGTATTATAAAA
  TCAATAATAATATGCAAACAGTTGTGCCTGTGTATTTGAACTACATACAGGTATGTTGTT
  ATTAACAGATATATTTAACATTTATTTACTATGGGAGCCATTTCCTAATTGAATTGCGTA
  ATTACTAGACCAGAATGCATATGCTACTATACATTGATTTACTGCCTGTTTTTACACTGC
  CATTACCTTTCATGTTATCCATGATGTTGAACATGGGAGGCATTTTTAATGGACCAAATT
  TTTAGAAAAATTAGTTTTTGGATTTTTTTTTAAGTTCTGTATACTGTTTTGAATGAACTT
  TATTTGCAGCTATTCTGGATGTCAGTTTAATAATTCAGGTACTGAATTTTATTGCTTGCT
  AATTGTGCCTTTCCGTTGCTAAATTAAGAAATGCTATGTGTACTGTGATGTAAAAATAAG
  ACATTAACTTTATCTTAAGTTACATATAATCAAGCAAATATTTTAAAAAATGTATGTCAG
  GGTGACAGGCATAAAAGTAAATTACCCTTAACTCTTTAGCCTTTATTTAGAAAGAAATGT
  GGAATGGGCTAAACTTTCTCACCAATTTATTAGAAAGCTAAATGGATAAATACTTCCCTT
  TTTGTAGATATTTTTCTGTGCATTGTAAGTTATAGGAGCAGGACATATTTTTTGTACATT
  GTCTTGATTGTTTATACTGCAGGTAGGTATTTCCAGTGAATGGAAACGTTGAAATTTATA
  GATGGGACAATGCACATACTTCATATGTAAACAAAGCATTTTTCTAAATAATTTGGAAAG
  GATTGGATTTAGCACCGTTAACTTTTAATACCCATTTATTGGCTATTTAAGGTAAATTAT
  AAAACCTAAAATTAGTATCAGTATTTTAGATCCTATTATTTTTTCAACTTTCTATTATTT
  TCACAGTGGAAAATTTGCGTATAGTATTAAACTATTCTTTTTTCTGTCTACCTTTATATT
  TTGAAGTGTGGTTGTACTTACGTTAATAGTAAGTGTATTTGTAGAAAGTTTTTCATAAAG
  AAGAGATTAACTTTCCATATAAATAAATACCAGGTATGAAATTACTGATTTTAGTGCAAT
  ATCTGTATGATTATCCAGAACTATCACTTCAGATGTTTCTATTTTGGGCACCATAACTAT
  TTGAGCTCATATTTTTATAATTCTGATTGAGAATTTAGGGGCATGGTAATTTTTACCAAA
  ACTGAAGCTGGTAATTTTAAGTAAAGCAACTAAATTTACCCTTTACTTATTAGTTAAAAG
  GAAACCAAGGCATGTAGGAAAATATTGGTACGTTGGAAAATGTGAAAAGAGCTTTACTTT
  CAAAATGTATGTTTAATGAATTGAATTTTAGGGACCGTTTCCCATAATTTGGGCCTATGC
  TATCCTGTTGATTTTTATGTCTAGCTTAAAAGGTATTTGAAAATGTTCCATTTGTGTTTT
  ATTATTTTCTGTCCTATGACAGTTCTATGCTAAATGTATTTTAAAATAAAAGCCAAATTG
  AAGATTAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for SC322734 unedited
  CCACGTACCATTGTATACGACTCCTATAGGGCGGCCGGAGATCGCGGCGCGCCGGTACCG
  GTCCGGAATTCCCGGGATGCGCTGTGCCGGTTCCGCTGCCGCTGGCCAGGAGCGCGGGGA
  CAGTTCGGGGCTGCGCCGGAGGCCGGCCCGCCTTCCCGGGGGTTCCGTTATCATGTCGCT
  GAGGCAGCGCCTGGCCCAGCTGGTTGGCCGTCTGCAGGACCCGCAGAAAGTGGCCCGTTT
  CCAGCGGCTGTGCGGGGTGGAAGCGCCGCCGCGCCGCTCAGCAGACCGGAGGGAGGATGA
  GAAAGCGGAGGCGCCTCTCGCCGGAGACCCTCGACTGCGAGGGCGGCAGCCAGGGGCGCC
  TGGAGGCCCCCAGCCTCCCGGGAGCGACCGCAATCAGTGCCCGGCCAAGCCGGACGGCGG
  CGGCGCCCCCAACGGCGTGCGGAACGGGCTGGCGGCCGAGCTGGGCCCGGCCTCGCCGCG
  GCGCGCGGGCGCTCTGCGCCGCAACTCGCTGACGGGCGAGGAGGGCCAGCTGGCCCGCGT
  GAGCAACTGGCCGCTCTACTGCCTGTTCTGCTTCGGCACGGAGCTGGGCAACGAACTCTT
  CTACATCCTGTTCTTCCCCTTCTGGATCTGGAACCTGGACCCTCTGGTGGCCGGAGGCTC
  GTGGTCATCTGGGTGCTGGTCATGTACCTGGGCCAGTGCACCAAGGACATCATCCCGCTG
  GCCGAGGCCCGCCTCGCCGCCCGTGGTCAAGTTTGGAGGTCTTCTACACTCTGAGTACAG
  CATGCCCTCCACCCATGCCATGTCCGGCACCGCATCCCATTTCTATGGGTCCCTCCTCAC
  TATGCCGCTGGCAGTAGCCTCTTATATATGAACTGAATCTTATTCCTGGCTAGATGATTC
  TCTAAGTTTGGCCCTAGTGATTTACTAGGAAATGCAGCTCAATTCGCACTTATTGCTGAA
  TTGCTATATACCATTTATACATCCTTAC
• Restriction Sites: Please inquire
• ACCN: NM_030791
• ORF Size: 1326 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_030791.2, NP_110418.1
• RefSeq Size: 3323
• RefSeq ORF: 1326
• Locus ID: 81537
• Domains: acidPPc
• Protein Families: Druggable Genome, Phosphatase, Transmembrane
• Protein Pathways: Sphingolipid metabolism
• Gene Summary: Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]). [supplied by OMIM, Jun 2009]