SPRED2 (NM_001128210) Human Untagged Clone

CAT#: SC323030

SPRED2 (untagged)-Human sprouty-related, EVH1 domain containing 2 (SPRED2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SPRED2
• Synonyms: Spred-2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001128210, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCATCGCCTGGCAGTGACAGCTATATTGTGCGTGTCAAGGCTGTGGTTATGACCAGAGATGACTCCA
  GCGGGGGATGGTTCCCACAGGAAGGAGGCGGGATCAGTCGCGTCGGGGTCTGTAAGGTCATGCACCCCGA
  AGGCAATGGACGAAGCGGCTTTCTCATCCATGGTGAACGACAGAAAGACAAACTGGTGGTATTGGAATGC
  TATGTAAGAAAGGACTTGGTCTACACCAAAGCCAATCCAACGTTTCATCACTGGAAGGTCGATAATAGGA
  AGTTTGGACTTACTTTCCAAAGCCCTGCTGATGCCCGAGCCTTTGACAGGGGAGTAAGGAAAGCAATCGA
  AGACCTTATAGAAGGTTCAACAACGTCATCTTCCACCATCCATAATGAAGCTGAGCTTGGCGATGATGAC
  GTTTTTACAACAGCTACAGACAGTTCTTCTAATTCCTCTCAGAAGAGAGAGCAACCTACTCGGACAATCT
  CCTCTCCCACATCCTGTGAGCACCGGAGGATTTATACCCTGGGCCACCTCCACGACTCATACCCCACAGA
  CCACTATCACCTCGATCAGCCGATGCCAAGGCCCTACCGCCAGGTGAGCTTCCCGGACGACGACGAGGAG
  ATCGTGCGCATCAACCCCCGGGAGAAGATCTGGATGACGGGGTACGAGGATTACCGGCACGCACCCGTCA
  GGGGCAAGTACCCGGACCCCTCGGAGGACGCGGACTCCTCCTACGTGCGCTTCGCCAAGGGCGAGGTCCC
  CAAGCATGACTACAACTACCCCTACGTGGACTCCTCAGACTTTGGCCTAGGCGAGGACCCCAAAGGCCGC
  GGGGGCAGCGTGATCAAGACGCAGCCCTCCCGGGGCAAGTCGCGGCGGCGGAAGGAGGACGGAGAGCGCT
  CGCGGTGCGTGTACTGCAGGGACATGTTCAACCACGAGGAGAACCGCCGGGGCCACTGCCAGGACGCGCC
  CGACTCCGTGAGAACTTGCATCCGCCGGGTGAGCTGCATGTGGTGCGCGGACAGCATGCTCTATCACTGT
  ATGTCGGACCCCGAGGGAGACTATACAGACCCTTGCTCGTGCGATACTAGCGACGAGAAGTTTTGCCTCC
  GGTGGATGGCTCTTATTGCCTTGTCTTTCCTGGCCCCCTGTATGTGCTGTTACCTGCCCCTTCGGGCCTG
  CTACCACTGCGGAGTGATGTGCAGGTGCTGTGGCGGGAAGCACAAAGCGGCCGCGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001128210
• ORF Size: 1248 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001128210.1, NP_001121682.1
• RefSeq Size: 4104
• RefSeq ORF: 1248
• Locus ID: 200734
• Protein Pathways: Jak-STAT signaling pathway
• Gene Summary: SPRED2 is a member of the Sprouty (see SPRY1; MIM 602465)/SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (see MAPK1; MIM 176948) (Nonami et al., 2004 [PubMed 15465815]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus compared to isoform a.