GPBP1 (NM_001127236) Human Untagged Clone

CAT#: SC323094

GPBP1 (untagged)-Human GC-rich promoter binding protein 1 (GPBP1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GPBP1
• Synonyms: GPBP; SSH6; VASCULIN
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001127236, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGCAGCATGACTTTGCTCCAGCCTGGCTTAATTTCCCTACTCCACCATCATCAACAAAGGTCCTGA
  CCAGCAGTTTGAAATCGTCATTGAATTTTGAGAAGCATTCTGAAAACTTTGCATGGACAGAGAATCGTTA
  TGATGTGAACCGTCGACGACACAACTCTTCAGATGGCTTTGATTCTGCTATTGGGCGTCCTAATGGAGGT
  AACTTTGGAAGGAAAGAAAAAAATGGATGGCGTACACATGGAAGAAATGGTACAGAAAACATAAATCATC
  GAGGTGGATACCATGGTGGAAGTTCCCGTTCTCGTAGCAGTATTTTCCATGCAGGAAAAAGCCAAGGACT
  ACATGAAAACAACATACCTGACAATGAAACCGGGAGGAAAGAAGACAAGAGAGAACGCAAACAGTTTGAA
  GCTGAGGATTTTCCGTCTTTAAATCCTGAGTATGAGAGAGAACCAAATCACAATAAGTCTTTAGCTGCAG
  GTGTGTGGGAATATCCTCCGAATCCTAAATCTAGAGCTCCAAGGATGCTGGTCATTAAGAAAGGTAATAC
  AAAAGACTTACAGCTATCTGGATTCCCAGTAGTAGGAAATCTTCCGTCACAGCCAGTTAAGAATGGAACT
  GGTCCAAGTGTTTATAAAGGTTTAGTCCCTAAACCTGCTGCTCCACCTACAAAACCTACACAATGGAAAA
  GCCAAACAAAAGAAAATAAAGTTGGAACTTCTTTCCCTCATGAGTCCACATTTGGCGTTGGCAACTTTAA
  TGCTTTTAAATCAACTGCCAAGAACTTTAGTCCATCTACAAATTCAGTGAAAGAGTGTAATCGCTCAAAT
  TCCTCTTCTCCTGTTGACAAACTTAATCAGCAGCCTCGTCTAACCAAACTGACACGAATGCGCACTGATA
  AGAAGAGTGAATTTTTGAAAGCATTGAAAAGAGACAGAGTAGAAGAGGAACATGAAGATGAAAGCCGTGC
  TGGCTCAGAGAAGGATGACGACTCATTTAATTTACATAACAGCAATAGTACTCACCAAGAAAGGGATATA
  AACCGAAACTTCGATGAAAATGAAATTCCTCAAGAGAATGGCAATGCCTCAGTGATTTCCCAGCAGATCA
  TTCGGTCTTCAACCTTCCCACAAACTGATGTTCTTTCAAGTTCACTTGAGGCAGAACACAGATTGTTAAA
  GGAAATGGGCTGGCAGGAAGACAGTGAAAATGATGAAACATGTGCTCCCTTAACTGAGGATGAAATGAGA
  GAATTCCAAGTTATTAGTGAACAGTTACAGAAGAATGGTCTGAGAAAAAATGGTATTTTGAAAAATGGCT
  TGATCTGTGACTTCAAGTTTGGACCGTGGAAGAACAGCACTTTCAAACCCACAACTGAGAATGATGACAC
  AGAGACAAGTAGCAGTGATACATCAGATGACGACGATGTGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001127236
• ORF Size: 1443 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001127236.2, NP_001120708.1
• RefSeq Size: 3437
• RefSeq ORF: 1443
• Locus ID: 65056
• Gene Summary: This gene was originally isolated by subtractive hybridization of cDNAs expressed in atherosclerotic plaques with a thrombus, and was found to be expressed only in vascular smooth muscle cells. However, a shorter splice variant was found to be more ubiquitously expressed. This protein is suggested to play a role in the development of atherosclerosis. Studies in mice suggest that it may also function as a GC-rich promoter-specific trans-activating transcription factor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
  Transcript Variant: This variant (2) contains an additional in-frame coding exon compared to variant 1, resulting in a longer isoform (2) with a 7 aa peptide fragment not found in isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.