SLC39A14 (NM_001128431) Human Untagged Clone

CAT#: SC323103

SLC39A14 (untagged)-Human solute carrier family 39 (zinc transporter), member 14 (SLC39A14), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC39A14
• Synonyms: cig19; HCIN; HMNDYT2; LZT-Hs4; NET34; ZIP14
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001128431 edited
  GGTCGGCGCGCGTGTCTACGCGGACGCACCGGCTAAGCTGCTTCTGCCGCCGCCGGCCGC
  CTGGGACCTTGCGGTGAGGCTGCGCGGGGCCGAGGCCGCCTCCGAGCGCCAGGTTTATTC
  AGTCACCATGAAGCTGCTGCTGCTGCACCCGGCCTTCCAGAGCTGCCTCCTGCTGACCCT
  GCTTGGCTTATGGAGAACCACCCCTGAGGCTCACGCTTCATCCCTGGGTGCACCAGCTAT
  CAGCGCTGCCTCCTTCCTGCAGGATCTAATACATCGGTATGGCGAGGGTGACAGCCTCAC
  TCTGCAGCAGCTGAAGGCCCTACTCAACCACCTGGATGTGGGAGTGGGCCGGGGTAATGT
  CACCCAGCACGTGCAAGGACACAGGAACCTCTCCACGTGCTTTAGTTCTGGAGACCTCTT
  CACTGCCCACAATTTCAGCGAGCAGTCGCGGATTGGGAGCAGCGAGCTCCAGGAGTTCTG
  CCCCACCATCCTCCAGCAGCTGGATTCCCGGGCCTGCACCTCGGAGAACCAGGAAAACGA
  GGAGAATGAGCAGACGGAGGAGGGGCGGCCAAGCGCTGTTGAAGTGTGGGGATACGGTCT
  CCTCTGTGTGACCGTCATCTCCCTCTGCTCCCTCCTGGGGGCCAGCGTGGTGCCCTTCAT
  GAAGAAGACCTTTTACAAGAGGCTGCTGCTCTACTTCATAGCTCTGGCGATTGGAACCCT
  CTACTCCAACGCCCTCTTCCAGCTCATCCCGGAGGCATTTGGTTTCAACCCTCTGGAAGA
  TTATTATGTCTCCAAGTCTGCAGTGGTGTTTGGGGGCTTTTATCTTTTCTTTTTCACAGA
  GAAGATCTTGAAGATTCTTCTTAAGCAGAAAAATGAGCATCATCATGGACACAGCCATTA
  TGCCTCTGAGTCGCTTCCCTCCAAGAAGGACCAGGAGGAGGGGGTGATGGAGAAGCTGCA
  GAACGGGGACCTGGACCACATGATTCCTCAGCACTGCAGCAGTGAGCTGGACGGCAAGGC
  GCCCATGGTGGACGAGAAGGTCATTGTGGGCTCGCTCTCTGTGCAGGACCTGCAGGCTTC
  CCAGAGTGCTTGCTACTGGCTGAAAGGTGTCCGCTACTCTGATATCGGCACTCTGGCCTG
  GATGATCACTCTGAGCGACGGCCTCCATAATTTCATCGATGGCCTGGCCATCGGTGCTTC
  CTTCACTGTGTCAGTTTTCCAAGGCATCAGCACCTCGGTGGCCATCCTCTGTGAGGAGTT
  CCCACCTGAGCTAGGAGACTTTGTCATCCTGCTCAACGCTGGGATGAGCATCCAACAAGC
  TCTCTTCTTCAACTTCCTTTCTGCCTGCTGCTGCTACCTGGGTCTGGCCTTTGGCATCCT
  GGCCGGCAGCCACTTCTCTGCCAACTGGATTTTTGCGCTAGCTGGAGGAATGTTCTTGTA
  TATTTCTCTGGCTGATATGTTCCCTGAGATGAATGAGGTCTGTCAAGAGGATGAAAGGAA
  GGGCAGCATCTTGATTCCATTTATCATCCAGAACCTGGGCCTCCTGACTGGATTCACCAT
  CATGGTGGTCCTCACCATGTATTCAGGACAGATCCAGATTGGGTAGGGCTCTGCCAAGAG
  CCTGTGGGACTGGAAGTCGGGCCCTGGGCTGCCCGATCGCCAGCCCGAGGACTTACCATC
  CACAATGCACCACGGAAGAGGCCGTTCTATGAAAAACTGACACAGACTGTATTCCTGCAT
  TCAAATGTCAGCCGTTTGTAAAATGCTGTATCCTAGGAATAAGCTGCCCTGGTAACCAGT
  CTCTAGCTAGTGCCTCTTGCCCTCTCCTCACCTCCTTTTCTCTCAGTGACTCTGGAACCT
  GAATGCAGCTTACAAGACAAGCCTGACTTTTTTCTCTGATTACCTTGGCCTCCTCTTGGA
  ACCAGTGCTGAAAGGTTTTGAATCCTTTACCCAACAATGCAAAAATAGAGCCAATGGTTA
  TAACTTGGCTAGAAATATCAAGAGTTGAATCCATAGTGTGGGGCCCATGACTCTAGCTGG
  GCACCTTGGACCTCCAGCTGGCCAATAGAAGAGACAGGAGACAGGAAGCCTTCCCATTTT
  TTCAAAGTCTGTTTAATTGCCTATTACTTCTCTCAAAGAGAACCTGAAGTCAGAACACAT
  GAGCAGGGTGAGAGGTGAGGCAAGGTTCATCCTGAATGGGAGAGGAAGTCGAACCACTGC
  TGTGTGTCTTGTCAGGATGCTCACTTGTTCCTACTGAGATGCTGGATATTGATTTTGTAA
  CAGCACCTGGTGTTTCACGGCTGTCCGAGTGAGCTAACGTGGCGGTGTGGCTGCCTGGAC
  CTCCTCTTTCAGGTTAACGCTGACAGAATGGAGGCTCAGGCTGTCTGCAAGAAAACAGTT
  GGTTTGGCTGTGATTTTGACCTCCTCTTCCCCACTGCCATCTTCTAAGAGACTTTGTAGC
  TGCCTCCTAGAAGCACATTCTGAGCACATTTGAGACCTCTGTGTTAGAGGGGAGACTGCA
  CAAACTATCCTCCCCCAGGTTGAGACGTCTGCAGAGTGGCAAGCTGACTTGTAGAAATGG
  GGTGCCATTTATGCTCTACTTAGACAAGGGTAATCAGAAATGGAATCAGTGCAGGCAAAA
  TTTAGGATTTGCCGCTTCCATAAATCAAAGCATGACTAATAGGGGGTCTCTGAAATGTAA
  GGGCACAAACTTCACTTAGGGCATCGCAGATGTTTGCAGAATGGTTGGCCTAATGATTAT
  GCTACAGATGGGTTTTAAATGACCCGTCTAGGTTACTGCTTCCTTGCAAAAAAAGTCGAA
  TCCTGCATTGAATTGAATATGAATTTCTCTAACTCTCTCCAGAAAATGGATGGAGATAAC
  TTGTCTTTAAAACTGTAGGCCAGCCTTAGCCACTGTGGAGCCCTTGCCTCCGAGCTCTGG
  CTTCAAGGGGAGCTCTTCTCCAGGTTCACTAGGTGAATTGATTTATTATTATCATATTGA
  TAATGTGAGATTCTTTAGCCACTTTGGGGAGCCTGTCTCTCCAGAAGCCTTTCTTAGTGG
  TGCCCACAGTTGGAGCCCAGGGGCCATGTTTGCAAACTGATTCATGTGCATGGCTGACAG
  GAGTACTGGTTCACTACCAATGCCTGAGCTTTTCTCTTACATAGAAAAACTGTCCGCTCT
  CAGTAATCACAAGCAGCATCCGTTTTGTTTTCTCTTCTTGGGAGACATCTGTCAAACCAG
  GAATATTCTTGAAAAGAACGTGAGCAGGAAAAACTGCTGGTGATACTTTTTTTAAGTTTT
  GTTTTTATCTTGCCTGTTGGCTTCAATACATTTGAGAATACGCTGAAGAGGGAAAATTTC
  AGTGATGGAGATTCTAGATTAAATATCAGGACTGATTTCCTGGTGGGATTATGGTCCAGT
  TTTATCAAAGAACCAATTCCTTGAATGTTGGAATCTAACTTTTTATATTGTCATTATTAT
  TGTTGTTTTTAAACGGTTCTTTGTCTTTTCTGTTTTATTTTTCTCAAGCTGCTTTCAGGA
  GCTAGCAGAAAATAACTCAAAGTTGAAGACTCTGGAAGATTTTGCTTTAACCTAACTCGC
  ATTGATGTATTAAATTTATAATTTTAGCATTCCCAATAGATCCTATCATTCCTTAAACAT
  AATACCCTTTGTCTTGGAGTAGAATACTAAGTTAGAGTTAGTGGATTTCTAGTTTAGGAG
  AGGAGCTCAAAACTATAATCTTTAACAAATTGAAAAATGAAATAGGGTGTTTTCCCTTTT
  TGTGCACACCTATATTACCTTAAGAAATTTCCTTCCATAGACAGCTGCCTCAAAGGGAAA
  TCCTCTTTAAACCGTAGTTGGCGCAGAGGTCAGTCCTAGTCGGAGCTTAGGAGGGGCGGA
  GACGCTCACATCGTCTGACTTGAGTCGCCACTGATTGTGGCAACAGCTTTGCCTCATGAG
  TCAAAAATTGGCAATTTCTTTTGATTTTTAGTTGTTGAATTTGCTGTTTCAAGCATTTGT
  ACATATTAGAAGTCTAAGGAGTAGCAAGTCAGTGGGAGGACTTTTTCACCCCTGGCATTA
  GCAGCTTCGACCTCATTTTCCAGATGCACCAGCTCCTATTAATAAGTTAGCAAGGAAAGT
  GTATGTCACGTGCAGGAACAGTGAGGCAGGGACAGGGGTTCTGCTCCTTCTCACTTCACC
  ACCGGCACACAGCTTGCCCCTGTCTTTGCCCCCAAAGGTATTTTGTGTCTAGTGTCAAAT
  TGGAGCTATTCTTCACTGGTCCTTAACCTTGGGTTTTAAAAAGAAGGCTTCTCTGTTTGG
  GTAGCGTAAGAGCTGAGTATAGTAAGTCCTCTTCCAAAGAGATGGCAATATGCTGGGCAT
  CTACTTTAAAACAAAGTTGTCTGATTTTTGCAAGAGAGGTTAGGATTTTATTGTTCTTAT
  TTCCCTTTACAGTTCTGCAGTTCCATCACAGTATTTTTTTAAATAACTCAGGTGTATGAG
  AAGAAATTAGAAAAGAAAATTAACTTATGTGGACTGTAAATGTTTTATTTGTAAGATTCT
  ATAAATAAAGCTATATTCTGTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001128431
• ORF Size: 1479 bp
• Insert Size: 4699
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001128431.1.

Reference Data

• RefSeq: NM_001128431.1, NP_001121903.1
• RefSeq Size: 4699
• RefSeq ORF: 1479
• Locus ID: 23516
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia. [provided by RefSeq, May 2017]
  Transcript Variant: This variant (1) encodes isoform a. Variants 1 and 3 encode the same protein.