PSD95 (DLG4) (NM_001128827) Human Untagged Clone

CAT#: SC323181

DLG4 (untagged)-Human discs, large homolog 4 (Drosophila) (DLG4), transcript variant 2


  "NM_001128827" in other vectors (2)

Reconstitution Protocol

USD 1,460.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol DLG4
Synonyms PSD95; SAP-90; SAP90
Vector PCMV6-Neo
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_001128827 edited
ATGGACTGTCTCTGTATAGTGACAACCAAGAAATACCGCTACCAAGATGAAGACACGCCC
CCTCTGGAGCACAGCCCGGCCCACCTCCCCAACCAGGCCAATTCTCCCCCAGTGATTGTC
AACACAGATACCCTAGAAGCCCCAGGATATGTGAACGGGACCGAGGGGGAGATGGAATAC
GAGGAAATCACATTGGAAAGGGGTAACTCAGGTCTGGGCTTCAGCATCGCAGGTGGCACT
GACAACCCACACATCGGTGACGACCCATCCATTTTCATCACCAAGATCATTCCTGGTGGG
GCTGCGGCCCAGGATGGCCGCCTCAGGGTCAACGACAGCATCCTGTTTGTAAATGAAGTG
GACGTGCGCGAGGTGACCCACTCAGCGGCGGTGGAAGCCCTCAAAGAGGCAGGCTCCATC
GTTCGCCTCTATGTCATGCGCCGGAAGCCCCCGGCTGAGAAGGTCATGGAGATCAAGCTC
ATCAAGGGGCCTAAAGGTCTTGGCTTCAGCATCGCAGGGGGCGTAGGGAACCAGCACATC
CCAGGAGATAATAGCATCTATGTAACAAAGATCATCGAAGGGGGTGCTGCCCACAAGGAT
GGGAGGTTGCAGATTGGAGACAAGATCCTGGCGGTCAACAGTGTGGGGCTAGAGGACGTC
ATGCATGAAGATGCTGTGGCAGCCCTGAAGAACACGTATGATGTTGTCTACCTAAAGGTG
GCCAAGCCCAGCAATGCCTACCTGAGTGACAGCTATGCTCCCCCAGACATCACAACCTCT
TATTCCCAGCACCTGGACAATGAGATCAGTCACAGCAGCTACCTGGGCACCGACTACCCC
ACAGCCATGACCCCCACTTCCCCTCGGCGCTACTCTCCAGTGGCCAAGGACCTGCTCGGG
GAGGAAGACATTCCCCGAGAACCGAGGCGAATTGTGATCCACCGGGGCTCCACGGGCCTG
GGCTTCAACATCGTGGGTGGCGAGGACGGTGAAGGCATCTTCATCTCCTTTATCCTGGCC
GGGGGCCCTGCAGACCTCAGTGGGGAGCTGCGGAAGGGGGACCAGATCCTGTCGGTCAAC
GGTGTGGACCTCCGAAATGCCAGCCATGAGCAGGCTGCCATTGCCCTGAAGAATGCGGGT
CAGACGGTCACGATCATCGCTCAGTATAAACCAGAAGAGTACAGCCGATTCGAGGCCAAG
ATCCACGACCTTCGGGAACAGCTCATGAACAGCAGCCTGGGCTCAGGGACTGCGTCCCTG
CGGAGCAACCCCAAAAGGGGTTTCTACATCAGGGCCCTGTTTGATTACGACAAGACCAAG
GACTGCGGCTTCCTGAGCCAGGCCCTGAGCTTCCGCTTTGGGGATGTGCTGCATGTCATC
GATGCTAGTGATGAGGAGTGGTGGCAGGCACGGCGGGTCCACTCTGACAGTGAGACCGAC
GACATTGGGTTCATCCCCAGCAAACGGCGGGTTGAGCGACGAGAGTGGTCAAGGTTAAAG
GCCAAGGACTGGGGCTCCAGCTCTGGATCGCAGGGTCGAGAAGACTCGGTTCTGAGCTAC
GAGACAGTGACGCAGATGGAAGTGCACTATGCTCGCCCCATCATCATCCTTGGGCCCACC
AAGGACCGCGCCAACGATGATCTTCTCTCCGAGTTCCCCGACAAGTTTGGATCCTGTGTT
CCCCATACGACACGGCCCAAGCGGGAGTATGAGATAGATGGCCGGGATTACCACTTTGTG
TCGTCCCGGGAGAAAATGGAGAAGGACATTCAGGCGCACAAGTTCATTGAGGCCGGCCAG
TACAACAGCCACCTCTATGGGACCAGCGTCCAGTCCGTGCGAGAGGTGGCAGAGCAGGGG
AAGCACTGCATCCTCGATGTCTCGGCCAATGCCGTGCGGCGGCTGCAGGCGGCCCACCTG
CACCCCATCGCCATCTTCATCCGCCCCCGCTCCCTGGAGAATGTGCTAGAGATTAACAAG
CGGATCACAGAGGAGCAAGCCCGCAAAGCCTTCGACAGAGCCACCAAGCTGGAGCAGGAG
TTCACAGAGTGCTTCTCAGCCATCGTGGAGGGTGACAGCTTTGAGGAGATCTACCACAAG
GTGAAGCGTGTCATCGAGGACCTCTCAGGCCCCTACATCTGGGTTCCAGCCCGAGAGAGA
CTCTGA
Restriction Sites Please inquire     
ACCN NM_001128827
Insert Size 2200 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_001128827.1, NP_001122299.1
RefSeq Size 3478 bp
RefSeq ORF 2166 bp
Locus ID 1742
Cytogenetics 17p13.1
Protein Families Druggable Genome
Protein Pathways Huntington's disease
Gene Summary 'This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (2) contains a distinct 5' UTR and 5' coding region and uses an alternate in-frame splice site, compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus and lacks a 3 amino acid internal segment when compared to isoform 1.

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