PSD95 (DLG4) (NM_001128827) Human Untagged Clone

CAT#: SC323181

DLG4 (untagged)-Human discs, large homolog 4 (Drosophila) (DLG4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DLG4
• Synonyms: PSD95; SAP-90; SAP90
• Vector: PCMV6-Neo
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001128827 edited
  ATGGACTGTCTCTGTATAGTGACAACCAAGAAATACCGCTACCAAGATGAAGACACGCCC
  CCTCTGGAGCACAGCCCGGCCCACCTCCCCAACCAGGCCAATTCTCCCCCAGTGATTGTC
  AACACAGATACCCTAGAAGCCCCAGGATATGTGAACGGGACCGAGGGGGAGATGGAATAC
  GAGGAAATCACATTGGAAAGGGGTAACTCAGGTCTGGGCTTCAGCATCGCAGGTGGCACT
  GACAACCCACACATCGGTGACGACCCATCCATTTTCATCACCAAGATCATTCCTGGTGGG
  GCTGCGGCCCAGGATGGCCGCCTCAGGGTCAACGACAGCATCCTGTTTGTAAATGAAGTG
  GACGTGCGCGAGGTGACCCACTCAGCGGCGGTGGAAGCCCTCAAAGAGGCAGGCTCCATC
  GTTCGCCTCTATGTCATGCGCCGGAAGCCCCCGGCTGAGAAGGTCATGGAGATCAAGCTC
  ATCAAGGGGCCTAAAGGTCTTGGCTTCAGCATCGCAGGGGGCGTAGGGAACCAGCACATC
  CCAGGAGATAATAGCATCTATGTAACAAAGATCATCGAAGGGGGTGCTGCCCACAAGGAT
  GGGAGGTTGCAGATTGGAGACAAGATCCTGGCGGTCAACAGTGTGGGGCTAGAGGACGTC
  ATGCATGAAGATGCTGTGGCAGCCCTGAAGAACACGTATGATGTTGTCTACCTAAAGGTG
  GCCAAGCCCAGCAATGCCTACCTGAGTGACAGCTATGCTCCCCCAGACATCACAACCTCT
  TATTCCCAGCACCTGGACAATGAGATCAGTCACAGCAGCTACCTGGGCACCGACTACCCC
  ACAGCCATGACCCCCACTTCCCCTCGGCGCTACTCTCCAGTGGCCAAGGACCTGCTCGGG
  GAGGAAGACATTCCCCGAGAACCGAGGCGAATTGTGATCCACCGGGGCTCCACGGGCCTG
  GGCTTCAACATCGTGGGTGGCGAGGACGGTGAAGGCATCTTCATCTCCTTTATCCTGGCC
  GGGGGCCCTGCAGACCTCAGTGGGGAGCTGCGGAAGGGGGACCAGATCCTGTCGGTCAAC
  GGTGTGGACCTCCGAAATGCCAGCCATGAGCAGGCTGCCATTGCCCTGAAGAATGCGGGT
  CAGACGGTCACGATCATCGCTCAGTATAAACCAGAAGAGTACAGCCGATTCGAGGCCAAG
  ATCCACGACCTTCGGGAACAGCTCATGAACAGCAGCCTGGGCTCAGGGACTGCGTCCCTG
  CGGAGCAACCCCAAAAGGGGTTTCTACATCAGGGCCCTGTTTGATTACGACAAGACCAAG
  GACTGCGGCTTCCTGAGCCAGGCCCTGAGCTTCCGCTTTGGGGATGTGCTGCATGTCATC
  GATGCTAGTGATGAGGAGTGGTGGCAGGCACGGCGGGTCCACTCTGACAGTGAGACCGAC
  GACATTGGGTTCATCCCCAGCAAACGGCGGGTTGAGCGACGAGAGTGGTCAAGGTTAAAG
  GCCAAGGACTGGGGCTCCAGCTCTGGATCGCAGGGTCGAGAAGACTCGGTTCTGAGCTAC
  GAGACAGTGACGCAGATGGAAGTGCACTATGCTCGCCCCATCATCATCCTTGGGCCCACC
  AAGGACCGCGCCAACGATGATCTTCTCTCCGAGTTCCCCGACAAGTTTGGATCCTGTGTT
  CCCCATACGACACGGCCCAAGCGGGAGTATGAGATAGATGGCCGGGATTACCACTTTGTG
  TCGTCCCGGGAGAAAATGGAGAAGGACATTCAGGCGCACAAGTTCATTGAGGCCGGCCAG
  TACAACAGCCACCTCTATGGGACCAGCGTCCAGTCCGTGCGAGAGGTGGCAGAGCAGGGG
  AAGCACTGCATCCTCGATGTCTCGGCCAATGCCGTGCGGCGGCTGCAGGCGGCCCACCTG
  CACCCCATCGCCATCTTCATCCGCCCCCGCTCCCTGGAGAATGTGCTAGAGATTAACAAG
  CGGATCACAGAGGAGCAAGCCCGCAAAGCCTTCGACAGAGCCACCAAGCTGGAGCAGGAG
  TTCACAGAGTGCTTCTCAGCCATCGTGGAGGGTGACAGCTTTGAGGAGATCTACCACAAG
  GTGAAGCGTGTCATCGAGGACCTCTCAGGCCCCTACATCTGGGTTCCAGCCCGAGAGAGA
  CTCTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001128827
• Insert Size: 2200 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001128827.1, NP_001122299.1
• RefSeq Size: 3478 bp
• RefSeq ORF: 2166 bp
• Locus ID: 1742
• Cytogenetics: 17p13.1
• Protein Families: Druggable Genome
• Protein Pathways: Huntington's disease
• Gene Summary: 'This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (2) contains a distinct 5' UTR and 5' coding region and uses an alternate in-frame splice site, compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus and lacks a 3 amino acid internal segment when compared to isoform 1.