NLRP7 (NM_001127255) Human Untagged Clone

CAT#: SC323251

NLRP7 (untagged)-Human NLR family, pyrin domain containing 7 (NLRP7), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NLRP7
• Synonyms: CLR19.4; HYDM; NALP7; NOD12; PAN7; PYPAF3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC323251 sequence for NM_001127255 edited (data generated by NextGen Sequencing)
  
  
  ATGACATCGCCCCAGCTAGAGTGGACTCTGCAGACCCTTCTGGAGCAGCTGAACGAGGATGAATTAAAGA
  GTTTCAAATCCCTTTTATGGGCTTTTCCCCTCGAAGACGTGCTACAGAAGACCCCATGGTCTGAGGTGGA
  AGAGGCTGATGGCAAGAAACTGGCAGAAATTCTGGTCAACACCTCCTCAGAAAATTGGATAAGGAATGCG
  ACTGTGAACATCTTGGAAGAGATGAATCTCACGGAATTGTGTAAGATGGCAAAGGCTGAGATGATGGAGG
  ACGGACAGGTGCAAGAAATAGATAATCCTGAGCTGGGAGATGCAGAAGAAGACTCGGAGTTAGCAAAGCC
  AGGTGAAAAGGAAGGATGGAGAAATTCAATGGAGAAACAATCTTTGGTCTGGAAGAACACCTTTTGGCAA
  GGAGACATTGACAATTTCCATGACGACGTCACTCTGAGAAACCAACGGTTCATTCCATTCTTGAATCCCA
  GAACACCCAGGAAGCTAACACCTTACACGGTGGTGCTGCACGGCCCCGCAGGCGTGGGGAAAACCACGCT
  GGCCAAAAAGTGTATGCTGGACTGGACAGACTGCAACCTCAGCCCGACGCTCAGATACGCGTTCTACCTC
  AGCTGCAAGGAGCTCAGCCGCATGGGCCCCTGCAGTTTTGCAGAGCTGATCTCCAAAGACTGGCCTGAAT
  TGCAGGATGACATTCCAAGCATCCTAGCCCAAGCACAGAGAATCCTGTTCGTGGTCGATGGCCTTGATGA
  GCTGAAAGTCCCACCTGGGGCGCTGATCCAGGACATCTGCGGGGACTGGGAGAAGAAGAAGCCGGTGCCC
  GTCCTCCTGGGGAGTTTGCTGAAGAGGAAGATGTTACCCAGGGCAGCCTTGCTGGTCACCACGCGGCCCA
  GGGCACTGAGGGACCTCCGGATCCTGGCGCAGCAGCCGATCTACGTAAGGGTGGAGGGCTTCCTGGAGGA
  GGACAGGAGGGCCTATTTCCTGAGACACTTTGGAGACGAGGACCAAGCCATGCGTGCCTTTGAGCTAATG
  AGGAGCAACGCGGCCCTGTTCCAGCTGGGCTCGGCCCCCGCGGTGTGCTGGATTGTGTGCACGACTCTGA
  AGCTGCAGATGGAGAAGGGGGAGGACCCGGTCCCCACCTGCCTCACCCGCACGGGGCTGTTCCTGCGTTT
  CCTCTGCAGCCGGTTCCCGCAGGGCGCACAGCTGCGGGGCGCGCTGCGGACGCTGAGCCTCCTGGCCGCG
  CAGGGCCTGTGGGCGCAGATGTCCGTGTTCCACCGAGAGGACCTGGAAAGGCTCGGGGTGCAGGAGTCCG
  ACCTCCGTCTGTTCCTGGACGGAGACATCCTCCGCCAGGACAGAGTCTCCAAAGGCTGCTACTCCTTCAT
  CCACCTCAGCTTCCAGCAGTTTCTCACTGCCCTGTTCTACACCCTGGAGAAGGAGGAGGGGGAGGACAGG
  GACGGCCACGCCTGGGACATCGGGGACGTACAGAAGCTGCTTTCCGGAGAAGAAAGACTCAAGAACCCCG
  ACCTGATTCAAGTAGGACACTTCTTATTCGGCCTCGCTAACGAGAAGAGAGCCAAGGAGTTGGAGGCCAC
  TTTTGGCTGCCGGATGTCACCGGACATCAAACAGGAATTGCTGCAATGCAAAGCACATCTTCATGCAAAT
  AAGCCCTTATCCGTGACCGACCTGAAGGAGGTCTTGGGCTGCCTGTATGAGTCTCAGGAGGAGGAGCTGG
  CGAAGGTGGTGGTGGCCCCGTTCAAGGAAATTTCTATTCACCTGACAAATACTTCTGAAGTGATGCATTG
  TTCCTTCAGCCTGAAGCATTGTCAAGACTTGCAGAAACTCTCACTGCAGGTAGCAAAGGGGGTGTTCCTG
  GAGAATTACATGGATTTTGAACTGGACATTGAATTTGAAAGGTGCACTTACCTAACCATTCCGAACTGGG
  CTCGGCAGGATCTTCGCTCTCTTCGCCTCTGGACAGATTTCTGCTCTCTCTTCAGCTCAAACAGCAACCT
  CAAGTTTCTGGAAGTGAAACAAAGCTTCCTGAGTGACTCTTCTGTGCGGATTCTTTGTGACCACGTAACC
  CGTAGCACCTGTCATCTGCAGAAAGTGGAGATTAAAAACGTCACCCCTGACACCGCGTACCGGGACTTCT
  GTCTTGCTTTCATTGGGAAGAAGACCCTCACGCACCTGACCCTGGCAGGGCACATCGAGTGGGAACGCAC
  GATGATGCTGATGCTGTGTGACCTGCTCAGAAATCATAAATGCAACCTGCAGTACCTGAGGTTGGGAGGT
  CACTGTGCCACCCCGGAGCAGTGGGCTGAATTCTTCTATGTCCTCAAAGCCAACCAGTCCCTGAAGCACC
  TGCGTCTCTCAGCCAATGTGCTCCTGGATGAGGGTGCCATGTTGCTGTACAAGACCATGACACGCCCAAA
  ACACTTCCTGCAGATGTTGTCGTTGGAAAACTGTCGTCTTACAGAAGCCAGTTGCAAGGACCTTGCTGCT
  GTCTTGGTTGTCAGCAAGAAGCTGACACACCTGTGCTTGGCCAAGAACCCCATTGGGGATACAGGGGTGA
  AGTTTCTGTGTGAGGGCTTGAGTTACCCTGATTGTAAACTGCAGACCTTGGTGTTACAGCAATGCAGCAT
  AACCAAGCTTGGCTGTAGATACCTCTCAGAGGCGCTCCAAGAAGCCTGCAGCCTCACAAACCTGGACTTG
  AGTATCAACCAGATAGCTCGTGGATTGTGGATTCTCTGTCAGGCGTTAGAGAATCCAAACTGTAACCTAA
  AACACCTACGCCTCTGGAGCTGCTCCCTCATGCCTTTCTATTGTCAGCATCTTGGATCTGCTCTCCTCAG
  CAATCAGAAGCTTGAAACTCTGGACCTGGGCCAGAATCATTTGTGGAAGAGTGGCATAATTAAGCTCTTT
  GGGGTTCTAAGACAAAGAACTGGATCCTTGAAGATACTCAGGTTGAAGACCTATGAAACTAATTTGGAAA
  TCAAGAAGCTGTTGGAGGAAGTGAAAGAAAAGAATCCCAAGCTGACTATTGATTGCAATGCTTCCGGGGC
  AACGGCACCTCCGTGCTGTGACTTTTTTTGCTGA
  
  Clone variation with respect to NM_001127255.1
  390:a=>g 929:g=>a 931:a=>c 1441:a=>g 2682:c=>t 2775:g=>a
• Restriction Sites: Please inquire
• ACCN: NM_001127255
• ORF Size: 3114 bp
• Insert Size: 3200
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to contain 3 SNPs compared with NM_001127255.1.

Reference Data

• RefSeq: NM_001127255.1, NP_001120727.1
• RefSeq Size: 3421
• RefSeq ORF: 3114
• Locus ID: 199713
• Gene Summary: This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) represents the longest transcript and encodes the longest isoform (3).