Tomosyn (STXBP5) (NM_001127715) Human Untagged Clone

CAT#: SC323260

STXBP5 (untagged)-Human syntaxin binding protein 5 (tomosyn) (STXBP5), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STXBP5
• Synonyms: LGL3; LLGL3; Nbla04300
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001127715, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGGAAATTCAACATCAGGAAGGTGCTGGACGGCCTGACCGCCGGCTCGTCCTCGGCGTCGCAGCAGC
  AACAGCAGCAGCATCCGCCTGGGAACCGGGAGCCGGAGATCCAGGAAACGCTCCAGTCCGAGCACTTTCA
  GCTCTGCAAGACTGTTCGCCATGGATTTCCCTATCAACCCTCAGCCCTGGCCTTTGATCCTGTACAGAAG
  ATCCTGGCAGTGGGAACTCAGACTGGTGCTTTAAGGCTCTTTGGTCGTCCAGGAGTAGAATGTTATTGCC
  AGCATGACAGTGGAGCTGCAGTAATCCAGCTCCAGTTCCTGATTAATGAGGGAGCGCTTGTGAGTGCCTT
  GGCTGATGACACCTTACACTTATGGAATTTACGTCAGAAGAGGCCTGCCATACTACATTCGCTTAAATTT
  TGCAGAGAAAGGGTTACATTTTGCCATCTGCCTTTCCAGAGTAAGTGGCTCTATGTGGGCACTGAACGAG
  GTAATATACATATTGTCAATGTGGAGTCCTTCACACTCTCAGGCTACGTCATTATGTGGAATAAAGCCAT
  TGAACTGTCATCTAAATCTCACCCAGGACCTGTGGTCCATATAAGTGATAATCCAATGGACGAGGGAAAG
  CTTTTGATTGGCTTTGAATCTGGAACAGTAGTTTTATGGGACCTCAAATCAAAGAAAGCCGACTACAGAT
  ACACATATGATGAGGCTATCCACTCTGTTGCTTGGCATCATGAAGGAAAACAATTTATTTGCAGTCATTC
  AGATGGCACCTTGACTATATGGAATGTAAGGTCCCCTGCTAAACCAGTACAGACAATCACTCCACATGGA
  AAACAGTTAAAGGATGGGAAGAAGCCAGAACCATGCAAACCTATCCTCAAGGTGGAATTCAAAACGACTA
  GATCTGGGGAGCCTTTTATTATTTTATCAGGAGGTTTGTCATATGATACTGTAGGAAGAAGACCTTGCTT
  AACAGTGATGCATGGGAAAAGCACTGCTGTGCTAGAAATGGACTATTCAATTGTTGATTTTCTAACGCTG
  TGTGAAACACCATACCCAAATGATTTTCAAGAACCATATGCTGTGGTTGTTCTTCTAGAAAAGGATTTAG
  TACTTATAGACCTTGCACAAAATGGATATCCTATATTTGAAAATCCCTACCCTTTGAGTATACATGAGTC
  CCCTGTTACATGTTGCGAATATTTTGCGGATTGTCCTGTGGACCTTATTCCTGCACTTTATTCTGTTGGA
  GCTAGACAGAAACGTCAAGGTTACAGCAAAAAGGAATGGCCCATCAACGGAGGTAATTGGGGCTTGGGTG
  CTCAAAGTTACCCAGAAATAATTATTACAGGGCATGCTGATGGGTCAGTTAAGTTCTGGGATGCTTCTGC
  AATAACTCTACAAGTATTATATAAGCTAAAGACATCTAAAGTATTTGAAAAGTCAAGAAATAAAGATGAC
  AGGCCAAACACAGACATTGTAGATGAAGATCCATATGCCATTCAGATCATCTCCTGGTGTCCAGAAAGTA
  GAATGCTGTGCATCGCTGGAGTTTCAGCTCATGTCATTATTTATAGATTCAGCAAGCAGGAAGTAATCAC
  AGAAGTCATTCCGATGCTTGAAGTTCGATTATTATATGAGATAAATGATGTGGAAACTCCGGAGGGTGAG
  CAGCCACCACCTTTGCCAACACCCGTGGGAGGGTCCAACCCTCAGCCCATCCCTCCTCAGTCTCATCCAT
  CTACCAGTAGCAGTTCATCTGATGGGCTTCGTGATAATGTACCTTGTTTAAAAGTTAAAAACTCACCACT
  TAAACAGTCTCCAGGTTATCAAACAGAACTAGTTATTCAGTTGGTTTGGGTGGGTGGAGAACCACCACAA
  CAAATAACCAGCCTGGCAGTCAATTCTTCCTATGGACTGGTGGTTTTTGGCAATTGCAATGGCATTGCTA
  TGGTTGACTACCTCCAGAAAGCAGTGCTGCTCAACCTGGGCACTATTGAATTATATGGCTCTAATGATCC
  TTATCGGAGAGAACCCCGATCTCCTCGTAAATCTCGACAGCCTTCAGGAGCCGGTCTGTGTGATATTAGT
  GAAGGGACTGTTGTTCCAGAGGATCGCTGCAAATCTCCAACCTCTGGTTCTTCATCACCACACAATTCAG
  ATGATGAACAAAAAATGAATAATTTTATAGAAAAGGTGAAGACCAAAAGCAGAAAGTTTTCCAAGATGGT
  AGCCAATGATATAGCAAAGATGTCAAGGAAGTTAAGCTTACCTACTGACCTAAAGCCTGATTTAGATGTA
  AAGGATAACTCCTTTAGCCGATCACGGAGTTCAAGTGTAACAAGCATTGACAAAGAATCCCGAGAAGCGA
  TCTCCGCTCTTCATTTCTGTGAAACGTTTACTCGAAAGACGGACTCGTCCCCTTCCCCTTGTCTATGGGT
  TGGAACAACGCTAGGAACAGTGCTTGTCATTGCACTGAACCTTCCCCCAGGGGGAGAGCAAAGACTTCTT
  CAGCCAGTAATTGTGTCTCCAAGTGGTACTATATTGAGGTTAAAAGGTGCAATCTTGAGAATGGCATTTC
  TGGATACCACAGGCTGCTTAATACCACCTGCGTATGAACCCTGGAGAGAGCACAATGTTCCTGAAGAAAA
  AGACGAAAAGGAGAAATTGAAAAAACGGCGGCCTGTCTCAGTATCCCCCTCCTCTTCTCAGGAAATTAGT
  GAAAACCAGTATGCAGTGATATGTTCTGAAAAGCAAGCAAAAGTAATCTCACTGCCAACCCAGAACTGTG
  CTTATAAGCAAAATATTACAGAGACCTCGTTTGTGCTTCGTGGAGATATTGTAGCATTGAGTAACAGTAT
  CTGCCTTGCCTGTTTCTGTGCCAATGGACATATAATGACTTTTAGTTTGCCAAGTTTAAGACCTCTGTTG
  GATGTGTATTACTTGCCCCTTACCAATATGCGGATAGCCAGAACGTTCTGCTTTACCAACAATGGACAAG
  CATTATACCTTGTTTCACCTACAGAAATCCAGAGACTTACTTATAGTCAAGAGACCTGTGAAAATCTTCA
  GGAAATGTTGGGTGAACTCTTCACTCCTGTAGAAACACCTGAAGCACCAAACAGGGGATTCTTTAAAGGC
  TTATTTGGAGGTGGTGCACAATCTCTTGACAGAGAAGAACTATTTGGAGAATCGTCCTCAGGAAAGGCTT
  CAAGGAGCCTTGCACAGCATATTCCTGGCCCTGGTGGCATTGAAGGCGTAAAAGGGGCAGCATCTGGAGT
  TGTTGGTGAATTAGCACGAGCCAGGCTGGCACTAGATGAAAGAGGGCAGAAACTTGGCGATCTGGAAGAA
  AGAACTGCGGCCATGTTATCAAGTGCAGAGTCATTTTCTAAACATGCTCATGAGATTATGTTGAAATACA
  AAGATAAGAAGTGGTACCAGTTCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001127715
• ORF Size: 3456 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001127715.2, NP_001121187.1
• RefSeq Size: 9352
• RefSeq ORF: 3456
• Locus ID: 134957
• Gene Summary: Syntaxin 1 is a component of the 7S and 20S SNARE complexes which are involved in docking and fusion of synaptic vesicles with the presynaptic plasma membrane. This gene encodes a syntaxin 1 binding protein. In rat, a similar protein dissociates syntaxin 1 from the Munc18/n-Sec1/rbSec1 complex to form a 10S complex, an intermediate which can be converted to the 7S SNARE complex. Thus this protein is thought to be involved in neurotransmitter release by stimulating SNARE complex formation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) contains an additional segment in the coding region, compared to variant 1, resulting in a longer isoform (b). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.