STK38L (NM_015000) Human Untagged Clone

CAT#: SC323597

STK38L (untagged)-Kinase deficient mutant (K119M) of Human serine/threonine kinase 38 like (STK38L)


  "NM_015000" in other vectors (7)

Reconstitution Protocol

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    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol STK38L
Synonyms NDR2
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC323597 sequence for NM_015000 edited (data generated by NextGen Sequencing)
ATGGCAATGACGGCAGGGACTACAACAACCTTTCCTATGAGCAACCATACCCGGGAAAGA
GTGACTGTAGCCAAGCTCACATTGGAGAATTTTTATAGCAACCTAATTTTACAGCATGAA
GAGAGAGAAACCAGGCAGAAGAAATTAGAAGTGGCCATGGAAGAAGAAGGATTAGCAGAT
GAAGAGAAAAAGTTACGTCGATCACAACACGCTCGCAAAGAAACAGAGTTCTTACGGCTC
AAAAGGACCAGACTTGGCTTGGATGACTTTGAGTCTCTGAAAGTTATAGGAAGAGGAGCT
TTTGGAGAGGTGCGGTTGGTCCAGAAGAAAGATACAGGCCATATCTATGCAATGATGATA
TTGAGAAAGTCTGATATGCTTGAAAAAGAGCAGGTGGCCCATATCCGAGCAGAAAGAGAT
ATTTTGGTAGAAGCAGATGGTGCCTGGGTGGTGAAGATGTTTTACAGTTTTCAGGATAAG
AGGAATCTTTATCTAATCATGGAATTTCTCCCTGGAGGTGACATGATGACATTGCTAATG
AAGAAAGACACCTTGACAGAAGAGGAAACACAGTTCTACATTTCAGAGACTGTTCTGGCA
ATAGATGCGATCCACCAGTTGGGTTTCATCCATCGGGATATTAAGCCAGACAACCTTTTA
TTGGATGCCAAGGGTCATGTAAAATTATCTGATTTTGGTTTATGTACGGGATTAAAGAAA
GCTCACAGGACTGAATTTTATAGAAATCTCACACACAACCCACCAAGTGACTTCTCATTT
CAGAACATGAACTCAAAGAGGAAAGCAGAAACTTGGAAGAAGAACAGGAGACAACTGGCA
TATTCCACAGTTGGGACACCAGATTACATTGCTCCAGAAGTATTCATGCAGACTGGTTAC
AACAAATTGTGTGACTGGTGGTCTTTGGGAGTGATTATGTATGAAATGCTAATAGGATAT
CCACCTTTCTGCTCTGAAACACCTCAAGAAACATACAGAAAAGTGATGAACTGGAAAGAA
ACTCTGGTATTTCCTCCAGAGGTACCTATATCTGAGAAAGCCAAGGACTTAATTCTCAGA
TTTTGTATTGATTCTGAAAACAGAATTGGAAATAGTGGAGTAGAAGAAATAAAAGGTCAT
CCCTTTTTTGAAGGTGTCGACTGGGAGCACATAAGGGAAAGGCCAGCAGCAATCCCTATA
GAAATCAAAAGCATTGATGATACTTCAAATTTTGATGACTTCCCTGAATCTGATATTTTA
CAACCAGTGCCAAATACCACAGAACCGGACTACAAATCCAAAGACTGGGTTTTTCTCAAT
TATACCTATAAAAGGTTTGAAGGGTTGACTCAACGTGGCTCTATCCCCACCTACATGAAA
GCTGGGAAGTTATGA

Clone variation with respect to NM_015000.3
356 a=>t;993 g=>a
>OriGene 5' read for mutant NM_015000 unedited
ACCGCCCGTTCAGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGA
ACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCGGCCGGCTGCGGT
CCGTGCGGAGGCTGAGCCGGCCGCGGGCGCGACCGGAGGCAGTTTCCGTTACTATGGCAATGACGGCAGG
GACTACAACAACCTTTCCTATGAGCAACCATACCCGGGAAAGAGTGACTGTAGCCAAGCTCACATTGGAG
AATTTTTATAGCAACCTAATTTTACAGCATGAAGAGAGAGAAAACCAGGGCAGAGGAAATTAGAAGTGGG
CCATGGAAGAGGAGGGATTAGCAGATGAAAGAGAAAAAAGTTACGGTCCGATCACACAACCACGGCTTCG
CCAAAGAAACACAGAAGTTTCTTTACCGGCCTCCAAAAGGGACCCAGAACTTGCCTGGGAAGGAACTTTG
AGATTCTCCTGGAAAGTTTTAGGAAGAAGGACCCTTTTGGGAAAGTGTGCGGTGTGGTCAGAAAAGAAGA
TACACAGGCCATATCATATGCATGGTAGGATTTTGAAAAGTCTCGTGATATGCTGAAAAAGAGAGCGTGG
GCCCTATACCCAGAACAGAAGAGAGATATTTTGGATAAAAACATAGGGCCCGGGTGTGGAAATATGTTAT
AACATTTTAGAGATAAGAGGACTCTTATCATACTCGGGAATTTTCCTCGGAGAGAGAGATGAGACTGTGC
ATAGAGGAGAGAGACCTTGCGCAGAGAGAACACGTTCTATTTTCAAACGTGTGTGGCATATCGCTCTCCC
CATGGGTTACATCTCGGGATATACGCAACCTTAATGATGTCACGCAGTTGAATCGGGTGCTGTACGGTAG
AAGTCACGAACGAATTAGATT
>SC323597 kinase domain raw sequence. By performing BLASTX analysis with this sequence against NCBI refernce protein database, you can confirm the presence of the kinase-deficient mutation
CTCGMGCATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCAG
AATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCGGCCGGCTGCGGTCCGTGCGG
AGGCTGAGCCGGCCGCGGGCGCGACCGGAGGCAGTTTCCGTTACTATGGCAATGACGGCAGGGACTACAA
CAACCTTTCCTATGAGCAACCATACCCGGGAAAGAGTGACTGTAG
Restriction Sites Please inquire     
ACCN NM_015000
ORF Size 1395 bp
Insert Size 4700
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This kinase-deficient mutant clone was generated by created by site-directed mutagenesis from the corresponding wild-type clone. See details in "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." Cell. 2008 May p536-548.
Reference Data
RefSeq NM_015000.1, NP_055815.1
RefSeq Size 4725
RefSeq ORF 1395
Locus ID 23012
Domains pkinase
Protein Families Druggable Genome, Protein Kinase
Gene Summary Involved in the regulation of structural processes in differentiating and mature neuronal cells. [UniProtKB/Swiss-Prot Function]

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