STK38L (NM_015000) Human Untagged Clone

CAT#: SC323597

STK38L (untagged)-Kinase deficient mutant (K119M) of Human serine/threonine kinase 38 like (STK38L)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STK38L
• Synonyms: NDR2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC323597 sequence for NM_015000 edited (data generated by NextGen Sequencing)
  ATGGCAATGACGGCAGGGACTACAACAACCTTTCCTATGAGCAACCATACCCGGGAAAGA
  GTGACTGTAGCCAAGCTCACATTGGAGAATTTTTATAGCAACCTAATTTTACAGCATGAA
  GAGAGAGAAACCAGGCAGAAGAAATTAGAAGTGGCCATGGAAGAAGAAGGATTAGCAGAT
  GAAGAGAAAAAGTTACGTCGATCACAACACGCTCGCAAAGAAACAGAGTTCTTACGGCTC
  AAAAGGACCAGACTTGGCTTGGATGACTTTGAGTCTCTGAAAGTTATAGGAAGAGGAGCT
  TTTGGAGAGGTGCGGTTGGTCCAGAAGAAAGATACAGGCCATATCTATGCAATGATGATA
  TTGAGAAAGTCTGATATGCTTGAAAAAGAGCAGGTGGCCCATATCCGAGCAGAAAGAGAT
  ATTTTGGTAGAAGCAGATGGTGCCTGGGTGGTGAAGATGTTTTACAGTTTTCAGGATAAG
  AGGAATCTTTATCTAATCATGGAATTTCTCCCTGGAGGTGACATGATGACATTGCTAATG
  AAGAAAGACACCTTGACAGAAGAGGAAACACAGTTCTACATTTCAGAGACTGTTCTGGCA
  ATAGATGCGATCCACCAGTTGGGTTTCATCCATCGGGATATTAAGCCAGACAACCTTTTA
  TTGGATGCCAAGGGTCATGTAAAATTATCTGATTTTGGTTTATGTACGGGATTAAAGAAA
  GCTCACAGGACTGAATTTTATAGAAATCTCACACACAACCCACCAAGTGACTTCTCATTT
  CAGAACATGAACTCAAAGAGGAAAGCAGAAACTTGGAAGAAGAACAGGAGACAACTGGCA
  TATTCCACAGTTGGGACACCAGATTACATTGCTCCAGAAGTATTCATGCAGACTGGTTAC
  AACAAATTGTGTGACTGGTGGTCTTTGGGAGTGATTATGTATGAAATGCTAATAGGATAT
  CCACCTTTCTGCTCTGAAACACCTCAAGAAACATACAGAAAAGTGATGAACTGGAAAGAA
  ACTCTGGTATTTCCTCCAGAGGTACCTATATCTGAGAAAGCCAAGGACTTAATTCTCAGA
  TTTTGTATTGATTCTGAAAACAGAATTGGAAATAGTGGAGTAGAAGAAATAAAAGGTCAT
  CCCTTTTTTGAAGGTGTCGACTGGGAGCACATAAGGGAAAGGCCAGCAGCAATCCCTATA
  GAAATCAAAAGCATTGATGATACTTCAAATTTTGATGACTTCCCTGAATCTGATATTTTA
  CAACCAGTGCCAAATACCACAGAACCGGACTACAAATCCAAAGACTGGGTTTTTCTCAAT
  TATACCTATAAAAGGTTTGAAGGGTTGACTCAACGTGGCTCTATCCCCACCTACATGAAA
  GCTGGGAAGTTATGA
  
  Clone variation with respect to NM_015000.3
  356 a=>t;993 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for mutant NM_015000 unedited
  ACCGCCCGTTCAGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGA
  ACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCGGCCGGCTGCGGT
  CCGTGCGGAGGCTGAGCCGGCCGCGGGCGCGACCGGAGGCAGTTTCCGTTACTATGGCAATGACGGCAGG
  GACTACAACAACCTTTCCTATGAGCAACCATACCCGGGAAAGAGTGACTGTAGCCAAGCTCACATTGGAG
  AATTTTTATAGCAACCTAATTTTACAGCATGAAGAGAGAGAAAACCAGGGCAGAGGAAATTAGAAGTGGG
  CCATGGAAGAGGAGGGATTAGCAGATGAAAGAGAAAAAAGTTACGGTCCGATCACACAACCACGGCTTCG
  CCAAAGAAACACAGAAGTTTCTTTACCGGCCTCCAAAAGGGACCCAGAACTTGCCTGGGAAGGAACTTTG
  AGATTCTCCTGGAAAGTTTTAGGAAGAAGGACCCTTTTGGGAAAGTGTGCGGTGTGGTCAGAAAAGAAGA
  TACACAGGCCATATCATATGCATGGTAGGATTTTGAAAAGTCTCGTGATATGCTGAAAAAGAGAGCGTGG
  GCCCTATACCCAGAACAGAAGAGAGATATTTTGGATAAAAACATAGGGCCCGGGTGTGGAAATATGTTAT
  AACATTTTAGAGATAAGAGGACTCTTATCATACTCGGGAATTTTCCTCGGAGAGAGAGATGAGACTGTGC
  ATAGAGGAGAGAGACCTTGCGCAGAGAGAACACGTTCTATTTTCAAACGTGTGTGGCATATCGCTCTCCC
  CATGGGTTACATCTCGGGATATACGCAACCTTAATGATGTCACGCAGTTGAATCGGGTGCTGTACGGTAG
  AAGTCACGAACGAATTAGATT
  
  Kinase domain sequence

  >SC323597 kinase domain raw sequence. By performing BLASTX analysis with this sequence against NCBI refernce protein database, you can confirm the presence of the kinase-deficient mutation
  CTCGMGCATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCAG
  AATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCGGCCGGCTGCGGTCCGTGCGG
  AGGCTGAGCCGGCCGCGGGCGCGACCGGAGGCAGTTTCCGTTACTATGGCAATGACGGCAGGGACTACAA
  CAACCTTTCCTATGAGCAACCATACCCGGGAAAGAGTGACTGTAG
  
• Restriction Sites: Please inquire
• ACCN: NM_015000
• ORF Size: 1395 bp
• Insert Size: 4700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This kinase-deficient mutant clone was generated by created by site-directed mutagenesis from the corresponding wild-type clone. See details in "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." Cell. 2008 May p536-548.

Reference Data

• RefSeq: NM_015000.1, NP_055815.1
• RefSeq Size: 4725
• RefSeq ORF: 1395
• Locus ID: 23012
• Domains: pkinase
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: Involved in the regulation of structural processes in differentiating and mature neuronal cells. [UniProtKB/Swiss-Prot Function]