STK39 (NM_013233) Human Untagged Clone
CAT#: SC323657
STK39 (untagged)-Kinase deficient mutant (K94M) of Human serine threonine kinase 39 (STE20/SPS1 homolog, yeast) (STK39)
"NM_013233" in other vectors (7)
Product Images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | STK39 |
Synonyms | DCHT; PASK; SPAK |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>NCBI ORF sequence for NM_013233, the custom clone sequence may differ by one or more nucleotides
ATGGCGGAGCCGAGCGGCTCGCCCGTGCACGTCCAGCTTCCCCAGCAGGCGGCCCCGGTGACAGCGGCGG CGGCGGCGGCCCCGGCGGCCGCGACAGCAGCGCCGGCCCCGGCAGCTCCCGCGGCCCCGGCCCCGGCCCC GGCCCCGGCGGCACAGGCTGTCGGCTGGCCCATCTGCAGGGACGCGTACGAGCTGCAGGAGGTTATCGGC AGTGGAGCTACTGCTGTGGTTCAGGCAGCCCTATGCAAACCCAGGCAAGAACGTGTAGCAATAAAACGGA TCAACTTGGAAAAATGCCAGACCAGTATGGATGAACTATTAAAAGAAATTCAAGCCATGAGTCAGTGCAG CCATCCCAACGTAGTGACCTATTACACCTCTTTTGTGGTCAAAGATGAACTTTGGCTGGTCATGAAATTA CTAAGTGGAGGTTCAATGTTGGATATCATAAAATACATTGTCAACCGAGGAGAACACAAGAATGGAGTTC TGGAAGAGGCAATAATAGCAACAATTCTTAAAGAGGTTTTGGAAGGCTTAGACTATCTACACAGAAACGG TCAGATTCACAGGGATTTGAAAGCTGGTAATATTCTTCTGGGTGAGGATGGTTCAGTACAAATAGCAGAT TTTGGGGTAAGTGCGTTCCTAGCAACAGGGGGTGATGTTACCCGAAATAAAGTAAGAAAAACATTCGTTG GCACCCCATGTTGGATGGCTCCTGAAGTCATGGAACAGGTGAGAGGCTATGACTTCAAGGCTGACATGTG GAGTTTTGGAATAACTGCCATTGAATTAGCAACAGGAGCAGCGCCTTATCACAAATATCCTCCCATGAAA GTGTTAATGTTGACTTTGCAAAATGATCCACCCACTTTGGAAACAGGGGTAGAGGATAAAGAAATGATGA AAAAGTACGGCAAGTCCTTTAGAAAATTACTTTCACTGTGTCTTCAGAAAGATCCTTCCAAAAGGCCCAC AGCAGCAGAACTTTTAAAATGCAAATTCTTCCAGAAAGCCAAGAACAGAGAGTACCTGATTGAGAAGCTG CTTACAAGAACACCAGACATAGCCCAAAGAGCCAAAAAGGTAAGAAGAGTTCCTGGGTCAAGTGGTCACC TTCATAAAACCGAAGACGGGGACTGGGAGTGGAGTGACGACGAGATGGATGAGAAGAGCGAAGAAGGGAA AGCAGCTTTTTCTCAGGAAAAGTCACGAAGAGTAAAAGAAGAAAATCCAGAGATTGCAGTGAGTGCCAGC ACCATCCCCGAACAAATACAGTCCCTCTCTGTGCACGACTCTCAGGGCCCACCCAATGCTAATGAAGACT ACAGAGAAGCTTCTTCTTGTGCCGTGAACCTCGTTTTGAGATTAAGAAACTCCAGAAAGGAACTTAATGA CATACGATTTGAGTTTACTCCAGGAAGAGATACAGCAGATGGTGTATCTCAGGAGCTCTTCTCTGCTGGC TTGGTGGATGGTCACGATGTAGTTATAGTGGCTGCTAATTTACAGAAGATTGTAGATGATCCCAAAGCTT TAAAAACATTGACATTTAAGTTGGCTTCTGGCTGTGATGGGTCGGAGATTCCTGATGAAGTGAAGCTGAT TGGGTTTGCTCAGTTGAGTGTCAGCTGA >OriGene 5' read for mutant NM_013233 unedited
CCCGCCCGTTATCAGCAAAGGGCGGTAGGCGCTGTACGGCTGTGGAGGTCTATATAAGCAGAGCTCGTTT AGTGAACCGTCAGAATCTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGTCCTAGCT GGCTTCGGCGGGGACGGCGGCGGCGGCGGCGGCGGCGGCGGCGGGCGGGGAGGGCGTGCGCCGGCCGAGA GGTGTCGGCGGCGAGGCAAAGGAAGTTTCAAGTGGAAGGTCGTCCGTCGGCCGGCGCGTCCTCCTGCTCT CCTCCGCAGCATCATGGCGGAGCCGAGCGGCTCGCCCGTGCACGTCCAGCTTTCCCCAGCAGGCGGGCCC CGGTGACAGCGGGCGGGCGGGCGGCGGCCCCGGCCCCGGCCCCGGCGGGCACAGGCTGTCGGCTTGGCCC TCCTGCAGGGACGCGTACGAGCTGCAGGAGGGTTATCGGCAGTGGAACCTACTGGTGGTGGTTCAGGCAG CCCAATGCCAAACCCAGGCAAAAAGTTGTACCATTAAGGCGGATCAACTTGAAAAATGCCGAACCAGTAG GGATAAACTATAAAAGAAATTCACCATTGATTCATGGGCACCCCTCCCAACGGTGGACCTATTACCCCTT TTTTGTTGTCAAATAAAATTTTGGCGTGGACATGAATTTCAAGGGGGGGTCAGTGTGATCTAAAACACTG TGACCCCGAGAACACCAAGGATTCGAGAAAAGAAAAAAACAATCTCTAAGTGTTTGAGCGCAACACTATC ACAACGCGCATCACAGAGTTAGACTGTGTATCTCTGTGGATGATGTAAAAAAAATTTTG >SC323657 kinase domain raw sequence. By performing BLASTX analysis with this sequence against NCBI refernce protein database, you can confirm the presence of the kinase-deficient mutation
AAAACCAGSACKMGAGTWCGGCAGTGGAGCTACTGCTGTGGTTCAGGCAGCCCTATGCAAACCCAGGCAA GAACGTGTAGCAATAATGCGGATCAACTTGGAAAAATGCCAGACCAGTATGGATGAACTATTAAAAGAAA TTCAAGCCATGAGTCAGTGCAGCCATCCCAACGTAGTGACCTATTACACCTCTTTTGTGGTCAAAGATGA ACTTTGGCTGGTCATGAAATTACTAAGTGGAGGTTCAATGTTGGA |
Restriction Sites | Please inquire |
ACCN | NM_013233 |
ORF Size | 1644 bp |
Insert Size | 3160 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This kinase-deficient mutant clone was generated by created by site-directed mutagenesis from the corresponding wild-type clone. See details in "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." Cell. 2008 May p536-548. |
Reference Data | |
RefSeq | NM_013233.1, NP_037365.1 |
RefSeq Size | 3293 |
RefSeq ORF | 1644 |
Locus ID | 27347 |
Domains | pkinase, TyrKc, S_TKc |
Protein Families | Druggable Genome, Protein Kinase |
Gene Summary | This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC115335 | STK39 (untagged)-Human serine threonine kinase 39 (STK39) |
USD 920.00 |
|
RC223981 | STK39 (Myc-DDK-tagged)-Human serine threonine kinase 39 (STK39) |
USD 480.00 |
|
RG223981 | STK39 (GFP-tagged) - Human serine threonine kinase 39 (STK39) |
USD 605.00 |
|
RC223981L1 | Lenti ORF clone of Human serine threonine kinase 39 (STK39), Myc-DDK-tagged |
USD 840.00 |
|
RC223981L2 | Lenti ORF clone of Human serine threonine kinase 39 (STK39), mGFP tagged |
USD 680.00 |
|
RC223981L3 | Lenti ORF clone of Human serine threonine kinase 39 (STK39), Myc-DDK-tagged |
USD 680.00 |
|
RC223981L4 | Lenti ORF clone of Human serine threonine kinase 39 (STK39), mGFP tagged |
USD 680.00 |
{0} Product Review(s)
Be the first one to submit a review