CDK15 (NM_139158) Human Untagged Clone
CAT#: SC323695
CDK15 (untagged)-Kinase deficient mutant (K81M) of Human PFTAIRE protein kinase 2 (PFTK2)
"NM_139158" in other vectors (7)
Product Images
![](https://cdn.origene.com/img/defaults-img-expression-plasmids.jpg)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | CDK15 |
Synonyms | ALS2CR7; PFTAIRE2; PFTK2 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC323695 sequence for NM_139158 edited (data generated by NextGen Sequencing)
ATGACTTCATTTCACCCCAGGGGACTTCAAGCTGCCCGTGCCCAGAAGTTCAAGAGTAAA AGGCCACGGAGTAACAGTGATTGTTTTCAGGAAGAGGATCTGAGGCAGGGTTTTCAGTGG AGGAAGAGCCTCCCTTTTGGGGCAGCCTCATCTTACTTGAACTTGGAGAAGCTGGGTGAA GGCTCTTATGCGACAGTTTACAAGGGGATTAGCAGAATAAATGGACAACTAGTGGCTTTA AWRGTCATCAGCATGAATGCAGAGGAAGGAGTCCCATTTACAGCTATCCGAGAAGCTTCT CTCCTGAAGGGTTTGAAACATGCCAATATTGTGCTCCTGCATGACATAATCCACACCAAA GAGACACTGACATTCGTTTTTGAATACATGCACACAGACCTGGCCCAGTATATGTCTCAG CATCCAGGAGGGCTTCATCCTCATAATGTCAGACTTTTCATGTTTCAACTTTTGCGGGGC CTGGCGTACATCCACCACCAACACGTTCTTCACAGGGACCTGAAACCTCAGAACTTACTC ATCAGTCACCTGGGAGAGCTCAAACTGGCTGATTTTGGTCTTGCCCGGGCCAAGTCCATT CCCAGCCAGACATACTCTTCAGAAGTCGTGACCCTCTGGTACCGGCCCCCTGATGCTTTG CTGGGAGCCACTGAATATTCCTCTGAGCTGGACATATGGGGTGCAGGCTGCATCTTTATT GAAATGTTCCAGGGTCAACCTTTGTTTCCTGGGGTTTCCAACATCCTTGAACAGCTGGAG AAAATCTGGGAGGTGCTGGGAGTCCCTACAGAGGATACTTGGCCGGGAGTCTCCAAGCTA CCTAACTACAATCCAGAATGGTTCCCACTGCCTACGCCTCGAAGCCTTCATGTTGTCTGG AACAGGCTGGGCAGGGTTCCTGAAGCTGAAGACCTGGCCTCCCAGATGCTAAAAGGCTTT CCCAGAGACCGCGTCTCCGCCCAGGAAGCACTTGTTCATGATTATTTCAGCGCCCTGCCA TCTCAGCTGTACCAGCTTCCTGATGAGGAGTCTTTGTTTACAGTTTCAGGAGTGAGGCTA AAGCCAGAAATGTGTGACCTTTTGGCCTCCTACCAGAAAGGTCACCACCCAGCCCAGTTT AGCAAATGCTGGTGA Clone variation with respect to NM_139158.1 242 a=>w;243 a=>r >OriGene 5' read for mutant NM_139158 unedited
ACCGCCGTCTGAGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGA ACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGAGGAGTCCCCAGAG AGGCAGGAGGAAAACCAAGGAAGTGCCCACTTCACAGAATCAAGGAGGCTTTCAAAAAGGGTGGCATGAT TATGGTGTTAAATGCCACCAAAGAGTAAAGCAAGGACTCTTGCTCTGTCACCCAGTCTGAAGTGCTGTGG CGCAACCATGGCTCTATGCAGCCTTGACCTCCTGAACTCAAGCAATTGTCCCTGCCTCAGCCTTCCCAGT TGCTGGGACCGCGGCTGCCTCGTTTTCAGTTTGTGCACATCTGATTGCCAAGCAATCCCGGTCTGAGGTG GAAGTTTCTTGCACTGATAAGGAAAAACTGCTGAGGTTGTGAGGCTGCTCCAAGGCCGAAGCATCATCCT ACCGGACTAAAAAGAAGGCTCATGGTTCCAGAGACTTCATTTACCCAAGGGAATCTTAAGCCGCGCCCTG TGCCAGAAATTTCAGAGAGTAAAAGGCACAGGGATATAACGTGTGATGTGTTTTCGAGAAGAGTCTCGAG GCACAGGTTTCAGTGGGGCGGAAGGGGAGACCCTCCTTTGGGCGCGCCCTCATCTCTTTAGATTTGGAAG ACTGTTGAAGCGCTCTTGCGCAGTTTCACAGGGGTATCACAGAATAGGCACTCTGTGTCTATAGTGTCTC ACGATGCCAGAGAGTCTCTATACTTCCAAGCTTCTCTCGAGGTTGAATGCACATGGTGCTGCGTGGATAT ACCACAGACCTCGATCTCGGTTGATCGACGAACTGCAAATTCATCAGGCTTCTATGGCACTAGTGACATC GGCTGCATCCACAGCGTAAGAACGAACTGACATCCCTA >SC323695 kinase domain raw sequence. By performing BLASTX analysis with this sequence against NCBI refernce protein database, you can confirm the presence of the kinase-deficient mutation
CTCGMGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCA GAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGAGGAGTCCCCAGAGAGGCAGG AGGAAAACCAAGGAAGTGCCCACTTCACAGAATCAAGGAGGCTTTCAAAAAGGGTGGCATGATTATGGTG TTAAATGCCACCAAAGAGTAAAGCAAGGATCTTGCTCTGTCACCC |
Restriction Sites | Please inquire |
ACCN | NM_139158 |
ORF Size | 1155 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This kinase-deficient mutant clone was generated by created by site-directed mutagenesis from the corresponding wild-type clone. See details in "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." Cell. 2008 May p536-548. |
Reference Data | |
RefSeq | NM_139158.1, NP_631897.1 |
RefSeq Size | 1534 |
RefSeq ORF | 1155 |
Locus ID | 65061 |
Protein Families | Druggable Genome, Protein Kinase |
Gene Summary | Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'. [UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) has an alternate in-frame 5' exon and initiates translation at an upstream AUG compared to variant 1. This results in a shorter protein (isoform 3) with a distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
SC120591 | CDK15 (untagged)-Human cyclin-dependent kinase 15 (CDK15) |
USD 660.00 |
|
RC219623 | CDK15 (Myc-DDK-tagged)-Human cyclin-dependent kinase 15 (CDK15) |
USD 420.00 |
|
RG219623 | CDK15 (GFP-tagged) - Human cyclin-dependent kinase 15 (CDK15) |
USD 460.00 |
|
RC219623L1 | Lenti ORF clone of Human cyclin-dependent kinase 15 (CDK15), Myc-DDK-tagged |
USD 768.00 |
|
RC219623L2 | Lenti ORF clone of Human cyclin-dependent kinase 15 (CDK15), mGFP tagged |
USD 620.00 |
|
RC219623L3 | Lenti ORF clone of Human cyclin-dependent kinase 15 (CDK15), Myc-DDK-tagged |
USD 620.00 |
|
RC219623L4 | Lenti ORF clone of Human cyclin-dependent kinase 15 (CDK15), mGFP tagged |
USD 620.00 |
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