GBA2 (NM_020944) Human Untagged Clone

CAT#: SC323811

GBA2 (untagged)-Human glucosidase, beta (bile acid) 2 (GBA2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GBA2
• Synonyms: AD035; NLGase; SPG46
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_020944.2 CTTCCCACGGGCTGGCACCTGGGCGCGGGCGCTGCCCCGGAGCCGGCCGGCGGGACCTGG
  CGCCCAATCCTGGGGGACCCGGTGCCGTGGCCCAGGGGCCGGGCCGAGGTCCCGGGGGCG
  GTGCCTTGCGGGCCCGTCCCGGGGCGGTGCCTGGTGGGCTGGCCCCGCGGCTCCTCCCCT
  CTCTGCGGGCCCAGTCGCCCTTTGGCCGGGCGAGCTAATCGTCGGCTCAATGACGACGAG
  GCCCGACCCTTCCCGTCCAGGACCTACAGAGACAACCGAAGGAGAGCCCAAGGCGGCTTC
  TTTGCTGTCGCCGCCCCCACTGAAGCAAGAGCTCCCCGGCTCCACTGAAACACCAGCTCA
  TTTAAGCTTTCCCCAACGCCCGGCCCTCCGGGACGATACCTAACAACGACCGGCGCCCGC
  ATCTGGAATAGGCTGGCGAGATACTTAGTATCCGAGGGCTCGGGACTTGGCGCCATCGAG
  GTCATGGGGACCCAGGATCCAGGGAACATGGGAACCGGCGTCCCAGCCTCGGAGCAGATA
  AGCTGTGCCAAAGAGGATCCACAAGTTTATTGCCCTGAAGAGACTGGCGGCACCAAGGAT
  GTGCAGGTTACAGACTGTAAGAGTCCCGAAGACAGCCGACCCCCAAAAGAGACGGACTGC
  TGCAATCCGGAGGACTCTGGGCAGCTGATGGTTTCCTATGAGGGTAAAGCTATGGGCTAC
  CAGGTGCCTCCCTTTGGCTGGCGCATCTGTCTGGCTCATGAGTTTACAGAGAAGAGGAAA
  CCCTTTCAAGCTAACAACGTCTCCCTAAGCAACATGATAAAGCATATAGGCATGGGCTTG
  AGGTACCTGCAGTGGTGGTACCGGAAGACCCATGTGGAAAAGAAGACACCTTTCATCGAC
  ATGATCAATTCTGTACCCCTAAGACAGATTTATGGTTGTCCCTTGGGTGGCATCGGGGGA
  GGCACTATTACCCGTGGCTGGAGAGGCCAGTTCTGTCGTTGGCAGCTTAACCCTGGAATG
  TATCAGCACCGGACAGTCATCGCTGACCAATTCACAGTGTGCCTGCGTCGGGAAGGGCAG
  ACTGTGTACCAGCAAGTCCTGTCCCTGGAGCGCCCAAGTGTCCTCCGCAGCTGGAACTGG
  GGCCTGTGTGGGTACTTTGCTTTCTACCATGCCCTCTATCCCCGAGCCTGGACTGTCTAT
  CAGCTTCCTGGCCAGAATGTCACCCTCACCTGCCGTCAGATCACACCCATCTTGCCCCAT
  GACTACCAGGACAGCAGCCTGCCTGTAGGAGTCTTTGTGTGGGATGTGGAAAATGAAGGG
  GACGAAGCTCTAGATGTGTCCATCATGTTCTCCATGCGGAATGGACTGGGTGGTGGAGAC
  GATGCCCCAGGGGGTTTGTGGAATGAGCCCTTCTGTCTGGAGCGTAGCGGGGAAACTGTC
  CGGGGGCTGCTCCTGCATCATCCAACCCTTCCAAACCCCTACACGATGGCTGTGGCTGCA
  CGAGTCACGGCAGCTACCACGGTAACCCACATCACAGCCTTTGACCCTGACAGCACGGGG
  CAGCAGGTGTGGCAGGATCTACTTCAGGATGGACAGCTGGACTCTCCCACTGGCCAAAGC
  ACCCCTACGCAGAAAGGAGTAGGCATTGCTGGAGCTGTGTGTGTTTCCAGCAAGTTGCGA
  CCTCGAGGCCAGTGCCGCCTGGAGTTTTCACTGGCTTGGGACATGCCCAGGATCATGTTT
  GGAGCTAAAGGCCAAGTCCACTACAGGCGGTATACAAGGTTCTTTGGCCAGGATGGAGAT
  GCAGCACCTGCCCTCAGCCACTATGCACTGTGCCGATACGCAGAGTGGGAAGAGAGGATC
  TCAGCTTGGCAGAGCCCGGTATTGGATGACAGATCACTGCCTGCCTGGTACAAATCTGCG
  CTGTTCAATGAACTATACTTCCTGGCTGATGGAGGCACAGTGTGGCTGGAAGTTCTTGAG
  GACTCCCTACCAGAGGAGCTGGGCAGAAACATGTGTCACCTCCGCCCCACCCTACGGGAC
  TACGGTCGATTTGGCTACCTTGAGGGCCAGGAGTACCGCATGTACAACACATATGATGTC
  CACTTTTATGCTTCCTTTGCCCTCATCATGCTCTGGCCCAAACTTGAGCTCAGCCTACAG
  TATGACATGGCTCTGGCCACTCTCAGGGAGGACCTGACACGGCGACGGTACCTGATGAGT
  GGGGTGATGGCACCTGTGAAAAGGAGGAACGTCATCCCCCATGATATTGGGGACCCAGAT
  GATGAACCATGGCTCCGCGTCAATGCATATTTAATCCATGATACTGCTGATTGGAAGGAC
  CTGAACCTGAAGTTTGTGCTGCAGGTTTATCGGGACTATTACCTCACGGGTGATCAAAAC
  TTCCTGAAGGACATGTGGCCTGTGTGTCTAGCTGTGATGGAATCTGAAATGAAGTTTGAC
  AAGGACCATGATGGACTCATTGAAAATGGAGGCTATGCAGACCAGACCTATGATGGATGG
  GTGACCACAGGCCCCAGTGCTTACTGTGGAGGGCTGTGGCTGGCAGCTGTGGCTGTGATG
  GTCCAGATGGCTGCTCTGTGTGGGGCACAGGACATCCAGGATAAGTTTTCTTCTATCCTC
  AGCCGGGGCCAAGAAGCCTATGAGAGACTGCTGTGGAATGGCCGCTATTACAACTATGAC
  AGCAGCTCTCGGCCTCAGTCTCGTAGTGTTATGTCTGACCAGTGTGCTGGACAGTGGTTC
  CTGAAGGCCTGTGGCCTAGGAGAAGGAGACACTGAGGTGTTTCCTACCCAACATGTGGTC
  CGTGCTCTCCAAACTATCTTTGAGCTGAACGTCCAGGCCTTTGCAGGAGGGGCCATGGGG
  GCTGTGAATGGGATGCAGCCCCATGGTGTCCCTGATAAATCCAGTGTGCAGTCTGATGAA
  GTCTGGGTGGGTGTGGTCTACGGGCTGGCAGCTACCATGATCCAAGAGGGCCTGACTTGG
  GAGGGCTTCCAGACAGCTGAAGGCTGCTACCGTACCGTGTGGGAGCGCCTGGGTCTGGCC
  TTCCAGACCCCAGAGGCATACTGCCAGCAGCGAGTGTTCCGCTCACTGGCCTACATGCGG
  CCACTGAGCATATGGGCCATGCAGCTAGCCCTGCAACAGCAGCAGCACAAAAAGGCCTCC
  TGGCCAAAAGTCAAACAGGGCACAGGACTAAGGACAGGGCCTATGTTTGGACCAAAGGAA
  GCCATGGCAAACCTGAGCCCAGAGTGAGCCGTCTGAACTGTGGGAGGGAAGTGCTAACAG
  CCCAGCCTCCAGCCTGGCCTTTCCTCCTTCCCCTCTGAACCTCCTGCAACCCTGAGCCAT
  CAGGACAATCATACCCCTTCCCTTCTCTCCACCCAATTGTGCCAGTAAATGGGGGTTGAG
  GGTGACCTAGGCAGCATTAGAATCACTTATTTATTTCTTTCCTCACCTGTTCCCTGACTG
  CGTGAAATGTTCAGGGAGGTCAGTTGATTTCCCCAGGTACATTCATGGTGTGACAGACAC
  ATGGGTACAAATAAAAGACCCAGAAAGCCATTAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020944.2 unedited
  GGCTATTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTCCG
  GAATTCCCGGGATATCGTCGACCCACGCGTCCGCTTCCCACGGGCTGGCACCTGGGCGCG
  GGCGCTGCCCCGGAGCCGGCCGGCGGGACCTGGCGCCCAATCCTGGGGGACCCGGTGCCG
  TGGCCCAGGGGCCGGGCCGAGGTCCCGGGGGCGGTGCCTTGCGGGCCCGTCCCGGGGCGG
  AGAAAAAAGGAAAAAAAAAAAAAAAAAAAAAAAAAAAACTTAAATAAGACAATTGCATAA
  AGCT
• Restriction Sites: ECoRI-NOT
• ACCN: NM_020944
• ORF Size: 2784 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_020944.2, NP_065995.1
• RefSeq Size: 3639
• RefSeq ORF: 2784
• Locus ID: 57704
• Domains: DUF608
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism. [provided by RefSeq, Jul 2008]