GBA2 (NM_020944) Human Tagged ORF Clone

CAT#: RC203706L4

Lenti ORF clone of Human glucosidase, beta (bile acid) 2 (GBA2), mGFP tagged

Specifications

Product Data

• Type: Human Tagged ORF Clone
• Tag: mGFP
• Symbol: GBA2
• Synonyms: AD035; NLGase; SPG46
• Vector: pLenti-C-mGFP-P2A-Puro
• E. coli Selection: Chloramphenicol (34 ug/mL)
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203706).
• Restriction Sites: SgfI-MluI Cloning Scheme for this gene
• ACCN: NM_020944
• ORF Size: 2781 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.

Reference Data

• RefSeq: NM_020944.2, NP_065995.1
• RefSeq Size: 3639
• RefSeq ORF: 2784
• Locus ID: 57704
• Domains: DUF608
• Protein Families: Druggable Genome
• MW: 104.6 kDa
• Gene Summary: This gene encodes a microsomal beta-glucosidase that catalyzes the hydrolysis of bile acid 3-O-glucosides as endogenous compounds. Studies to determine subcellular localization of this protein in the liver indicated that the enzyme was mainly enriched in the microsomal fraction where it appeared to be confined to the endoplasmic reticulum. This putative transmembrane protein is thought to play a role in carbohydrate transport and metabolism. [provided by RefSeq, Jul 2008]