DLX3 (NM_005220) Human Untagged Clone

CAT#: SC323820

DLX3 (untagged)-Human distal-less homeobox 3 (DLX3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DLX3
• Synonyms: AI4; TDO
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005220.2 GCTTGGGACGCGAGGAGAGGCGCGCAGCGACCGCCTGACGGCAGGCAATGGTGTAAGCGC
  CTCTCGGCCTCCCCCTCCCCCCAGACGCGGCCGGGTCCTCCCTTCGCCTTCTGGACACAC
  ACCCCTGCCTCGTCTCTTCCGCCTCTCTTGCACTCCGGTCCGTTCCTGTCCTCTGCGGAG
  GCCAGCCCTGGGGAGGTGCAGCGCCCGCCAGGATGAGTGGCTCCTTCGATCGCAAGCTCA
  GCAGCATCCTCACCGACATCTCCAGCTCCCTTAGCTGCCATGCGGGCTCCAAGGACTCGC
  CTACCCTGCCCGAGTCTTCTGTCACTGACCTGGGCTACTACAGCGCTCCCCAGCACGATT
  ACTACTCGGGCCAGCCCTATGGCCAGACGGTGAACCCCTACACCTACCACCACCAATTCA
  ATCTCAATGGGCTTGCAGGCACGGGCGCTTACTCGCCCAAGTCGGAATATACCTACGGAG
  CCTCCTACCGGCAATACGGGGCGTATCGGGAGCAGCCGCTGCCAGCCCAGGACCCAGTGT
  CGGTGAAGGAGGAGCCGGAAGCAGAGGTGCGCATGGTGAATGGGAAGCCCAAGAAGGTCC
  GAAAGCCGCGTACAATCTACTCCAGCTACCAGCTGGCCGCCCTGCAGCGCCGCTTCCAGA
  AGGCCCAGTACCTGGCGCTGCCCGAGCGCGCCGAGCTGGCCGCGCAGCTGGGCCTCACGC
  AGACACAGGTGAAAATCTGGTTCCAGAACCGCCGTTCCAAGTTCAAGAAACTCTACAAGA
  ACGGGGAGGTGCCGCTGGAGCACAGTCCCAATAACAGTGATTCCATGGCCTGCAACTCAC
  CACCATCACCCGCCCTCTGGGACACCTCTTCCCACTCCACTCCGGCCCCTGCCCGCAGTC
  AGCTGCCCCCGCCGCTCCCATACAGTGCCTCCCCCAGCTACCTGGACGACCCCACCAACT
  CCTGGTATCACGCACAGAACCTGAGTGGACCCCACTTACAGCAGCAGCCGCCTCAGCCAG
  CCACCCTGCACCATGCCTCTCCCGGGCCCCCGCCCAACCCTGGGGCTGTGTACTGAGCAC
  CCATCTGGCCTGCACCCTTGACAAAGGACCCCAGGACCAGGCAGAAGGCGCCTCCGTCCT
  AGCCACTCAGGAATCATCGAGGAGCACAGGGAAAAGGAACTCCCTTTCCCCCTCCCTTGC
  CCCTTCCTCCAGGGACCCAAGCGCTTCCAGATGACATTTGCATGGACCAAGGATGCCCCC
  TGAACCTCCCTCCCTCTGCCTAGACACTGGGGTACCCCTCCAGATGTGGGGACATTCCAC
  CCCAGTGGGGACAGCCATTCCCCTACCTGCTCCAGGAGCCTGGATTGGCTTTAAATGGCT
  CATCATCTTCCAGCTTCTTAAACTTAGTGCCTGTTCCCAGACTGGAGACCTTGGGATGGG
  GGAGAGTGTGGAGGGTTTGCGGGTCCTGCCTGTGCTGGGGCACCTGGCACCGTGGATCTT
  AAAACTTGCCAGGCCTAGTTCCTCCTGAGCCTCTGGTGGTCTCCCCCTGCTCGAGCGGCC
  CCTCGGCCAATAAGACAGTGGACATCATGACGAGGACTCCGGGTGGGGACCTGAACTGGT
  CACCGCCCTGCACTTCTAGCCCTCATTTAAGATTTGAGGGTGAAACCAAAGAAAACCCCC
  TAAGTGAGGGAATCTTTTAATATTTGTGGCTTTAGAGGAAAGAACTAAAGGAGCCATCTC
  TCTCCCCTCTCCTCCGTTCCGAGAGGAGGGGTGGGTCTCAGACGTTTTTCCTATGGACTT
  ATTTCTTCCATGTCCAGGACTTTGCACAACTTTGGTTTTAAAAGCTGTTGAAAAATAGGA
  AAACAAAGGGCATTGTTCACAGATAGGGCCAAGTCTCCCCTTGCAAGGGTGCCTCTGTTC
  TGTCCCTGCCCCCACCTCACCTTCTCTACTCCTCCAGTAAGTTGGCAGTTTTGGTGCCAA
  ACCCCAAATCTCCAAAGAGACATACCAGGCAAGACAAACCCCCAAACACCTCCTTTCCGG
  TGGCCTTGGAAACAGATTGCTCCGAGCTGGAGAATGTCGGGTGAGGTGTATGGGAGAGGA
  GGGGAGAGTTAGAACTTGTGCCTTTGGGAGTAAGGGGTAACTGCCTGGAGGGCTGGTGGC
  ACTGCCCCTCCCTGACCCAGACATCCCACCAAAGCTAACTTTCCCCCACCCCTGATGCAG
  TAAAACATTGAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005220.2 unedited
  GGCATTTGAATGTTACACGAACATACTTCTAGGGCGGCCGGCGACTCGCGGCGCGCCGGT
  TACCGGTCCGGAATTTCCCGGGATATCGTCGACCCACGCGTCCGGCTTGGGACGCGAGGA
  GAGGCGCGCAGCGACCGCCTGACGGCAGGCAATGGTGTAAGCGCCTCTCGGCCTCCCCCT
  CCCCCCAGACGCGGCCGGGTCCTCCCTTCGCCTTCTGGACACACACCCCTGCCTCGTCTC
  TTCCGCCTCTCTTGCACTCCGGTCCGTTCCTGTCCTCTGCGGAGGCCAGCCCTGGGGAGG
  TGCAGCGCCCGCCAGGATGAGTGGCTCCTTCGATCGCAAGCTCAGCAGCATCCTCACCGA
  CATCTCCAGCTCCCTTAGCTGCCATGCGGGCTCCAAGGACTCGCCTACCCTGCCCGAGTC
  TTCTGTCACTGACCTGGGCTACTACAGCGCTCCCCAGCACGATTACTACTCGGGCCAGCC
  CTATGGCCAGACGGTGAACCCCTACACCTACCACCACCAATTCAATCTCAATGGGCTTGC
  AGGCACGGGCGCTTACTCGCCCAAGTCGGAATATACCTACGGAGCCTCCTACCGGCAATA
  CGGGGCGTATCGGGAGCAGCCGCTGCCAGCCCAGGACCCAGTGTCGGTGAAGGAGGAGCC
  GGAAGCAGAGGTGCGCATGGTGAATGGGAAGCCCAAGACGTCCGAAAGCCGCGTACAATC
  TACTCCAGCTACCAGCTGGCCGCCCTGCAGCGCGCTTCCAGAAGCCCATACCTGGCGCTG
  CCCGAGCGCGCCGAGCTGACCTCGCAACTGGACCTCCGCGACCCAGGTGATAATCCGTTC
  CTGAACCCCCGTGTCATGTCAGGAAATCTCAGACGGGGAGCGGCCGCTGAGCACAACGAC
  AC
• Restriction Sites: ECoRI-NOT
• ACCN: NM_005220
• ORF Size: 864 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005220.2, NP_005211.1
• RefSeq Size: 2613
• RefSeq ORF: 864
• Locus ID: 1747
• Domains: homeobox
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. Trichodentoosseous syndrome (TDO), an autosomal dominant condition, has been correlated with DLX3 gene mutation. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17. Mutations in this gene have been associated with the autosomal dominant conditions trichodentoosseous syndrome and amelogenesis imperfecta with taurodontism. [provided by RefSeq, Jul 2008]