KLF1 (NM_006563) Human Untagged Clone

CAT#: SC323869

KLF1 (untagged)-Human Kruppel-like factor 1 (erythroid) (KLF1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KLF1
• Synonyms: EKLF; EKLF/KLF1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_006563.2 CTTGAGGCCCAGGGTGGGCACCAGCCAGCCATGGCCACAGCCGAGACCGCCTTGCCCTCC
  ATCAGCACACTGACCGCCCTGGGCCCCTTCCCGGACACACAGGATGACTTCCTCAAGTGG
  TGGCGCTCCGAAGAGGCGCAGGACATGGGCCCGGGTCCTCCTGACCCCACGGAGCCGCCC
  CTCCACGTGAAGTCTGAGGACCAGCCCGGGGAGGAAGAGGACGATGAGAGGGGCGCGGAC
  GCCACCTGGGACCTGGATCTCCTCCTCACCAACTTCTCGGGCCCGGAGCCCGGTGGCGCG
  CCCCAGACCTGCGCTCTGGCGCCCAGCGAGGCCCCCGGGGCGCAATATCCGCCGCCGCCC
  GAGACTCTGGGCGCATATGCTGGCGGCCCGGGGCTGGTGGCTGGGCTTTTGGGTTCGGAG
  GATCACTCGGGTTGGGTGCGCCCTGCCCTGCGAGCCCGGGCTCCCGACGCCTTCGTGGGC
  CCAGCCCTGGCTCCAGCCCCGGCCCCCGAGCCCAAGGCGCTGGCGCTGCAACCGGTGTAC
  CCGGGGCCCGGCGCCGGCTCCTCGGGTGGCTACTTCCCGCGGACCGGGCTTTCAGTGCCT
  GCGGCGTCGGGCGCCCCCTACGGGCTACTGTCCGGGTACCCCGCGATGTACCCGGCGCCT
  CAGTACCAAGGGCACTTCCAGCTCTTCCGCGGGCTCCAGGGACCCGCGCCCGGTCCCGCC
  ACGTCCCCCTCCTTCCTGAGTTGTTTGGGACCCGGGACGGTGGGCACTGGACTCGGGGGG
  ACTGCAGAGGATCCAGGTGTGATAGCCGAGACCGCGCCATCCAAGCGAGGCCGACGTTCG
  TGGGCGCGCAAGAGGCAGGCAGCGCACACGTGCGCGCACCCGGGTTGCGGCAAGAGCTAC
  ACCAAGAGCTCCCACCTGAAGGCGCATCTGCGCACGCACACAGGGGAGAAGCCATACGCC
  TGCACGTGGGAAGGCTGCGGCTGGAGATTCGCGCGCTCGGACGAGCTGACCCGCCACTAC
  CGGAAACACACGGGGCAGCGCCCCTTCCGCTGCCAGCTCTGCCCACGTGCTTTTTCGCGC
  TCTGACCACCTGGCCTTGCACATGAAGCGCCACCTTTGAGCCCTGCCCTGGCACTTGGAC
  TCTCCTAGTGACTGGGGATGGGACAAGAAGCCTGTTTGGTGGTCTCTTCACACGGACGCG
  CGTGACACAATGCTGGGTGGTTTTCCCACGAATGGACCCTCTCCTGGACTCGCGTTCCCA
  AAGATCCACCCAAATATCAAACACGGACCCATAGACAGCCCTGGGGGAGCCTCTTACGGA
  AAATCCGACAAGCCTTCAGCCACAGGGAGCCACACAGAGATGTCCAAACTGTCGTGCAAA
  CCCAGTGAGACAGACCGCCAAATAAACGGACTCAGTGGACACTCAGACCAGCTCCCAGAT
  GGCCCTGGACAGCAGGAGAGGGTGTGGGATGAGGCTTCCCAGAGACCCTGGGTCTAGAAA
  GCGGCTCCTGAAGGTCCCTTATTGTGGCTGATATTAACTGTCAATGGTTATGGGTCCTAT
  AAAAATGCCCCTCCCAGATAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006563.2 unedited
  GACACCTTGTATACGACTCCTATAGGGCGGCCGGCGTATCGCGGCGCGCCGGTACCGGTC
  CGGAATTCCCGGGATCTTGAGGCCCAGGGTGGGCACCAGCCAGCCATGGCCACAGCCGAG
  ACCGCCTTGCCCTCCATCAGCACACTGACCGCCCTGGGCCCCTTCCCGGACACACAGGAT
  GACTTCCTCAAGTGGTGGCGCTCCGAAGAGGCGCAGGACATGGGCCCGGGTCCTCCTGAC
  CCCACGGAGCCGCCCCTCCACGTGAAGTCTGAGGACCAGCCCGGGGAGGAAGAGGACGAT
  GAGAGGGGCGCGGACGCCACCTGGGACCTGGATCTCCTCCTCACCAACTTCTCGGGCCCG
  GAGCCCGGTGGCGCGCCCCAGACCTGCGCTCTGGCGCCCAGCGAGGCCCCCGGGGCGCAA
  TATCCGCCGCCGCCCGAGACTCTGGGCGCATATGCTGGCGGCCCGGGGCTGGTGGCTGGG
  CTTTTGGGTTCGGAGGATCACTCGGGTTGGGTGCGCCCTGCCCTGCGAGCCCGGGCACCC
  GACGCCTTGGTGGGCACAGCCATGGGTCCAGCCCCAGGCGGGGGGGGGTCGAGGCACTTG
• Restriction Sites: ECoRI-NOT
• ACCN: NM_006563
• ORF Size: 1089 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_006563.2, NP_006554.1
• RefSeq Size: 1618
• RefSeq ORF: 1089
• Locus ID: 10661
• Protein Families: Transcription Factors
• Gene Summary: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009]