WRCH1 (RHOU) (NM_021205) Human Untagged Clone

CAT#: SC323988

RHOU (untagged)-Human ras homolog gene family, member U (RHOU), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RHOU
• Synonyms: ARHU; CDC42L1; G28K; hG28K; WRCH1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021205.4 CGGCGCTCGGACCGCTGTCCTCCAACAGCGCAGGGCAGAGCGGCTGGCGCCGCCGGAGCG
  CGGAGCCACGACCCTCCCTGGCCGCCTTTGTCTACTGGCCGTGCGGCCCGGAACCGCCAC
  TCTCCAGGGCCGGGGACGCGCCCGCAGCTGTCGGTGACAGCTCCTCCCTACCGCAACCCT
  CCGGGGCGGAGGGGCGGTCGGGCCGGGCCCTGCTAGCCCGCGACCGCAAGCCCGCGCTCG
  CGGATCGATGCCCCCGCAGCAGGGGGACCCCGCGTTCCCCGACCGCTGCGAGGCGCCTCC
  GGTGCCGCCGCGTCGGGAGCGCGGTGGACGCGGGGGACGCGGGCCTGGGGAGCCGGGGGG
  CCGGGGGCGTGCGGGGGGTGCCGAGGGGCGCGGCGTCAAGTGCGTGCTGGTCGGCGACGG
  CGCGGTGGGCAAGACGAGCCTGGTGGTGAGCTACACCACCAACGGCTACCCCACCGAGTA
  CATCCCTACTGCCTTCGACAACTTCTCCGCGGTGGTGTCTGTGGATGGGCGGCCCGTGAG
  ACTCCAACTCTGTGACACTGCCGGACAGGATGAATTTGACAAGCTGAGGCCTCTCTGCTA
  CACCAACACAGACATCTTCCTGCTCTGCTTCAGTGTCGTGAGCCCCTCATCCTTCCAGAA
  CGTCAGTGAGAAATGGGTGCCGGAGATTCGATGCCACTGTCCCAAAGCCCCCATCATCCT
  AGTTGGAACGCAGTCGGATCTCAGAGAAGATGTCAAAGTCCTCATTGAGTTGGACAAATG
  CAAAGAAAAGCCAGTGCCTGAAGAGGCGGCTAAGCTGTGCGCCGAGGAAATCAAAGCCGC
  CTCCTACATCGAGTGTTCAGCCTTGACTCAAAAAAACCTCAAAGAGGTCTTTGATGCAGC
  CATCGTCGCTGGCATTCAATACTCGGACACTCAGCAACAGCCAAAGAAGTCTAAAAGCAG
  GACTCCAGATAAAATGAAAAACCTCTCCAAGTCCTGGTGGAAGAAGTACTGCTGTTTCGT
  ATGATGCTGGCAAGACACCCAGAAAGGCTATTTTCAGATGAAATCGATATTAGAAGCTAT
  ATTAGCTGAAACAACTCCTTTTACTGCGTAGAACCTATATCGAGAGTGTGTGTATATGTA
  TTATAGGAGGAGCTCTCAATTTTATGTATTCTTTCTGCCTTTAATTTTCTTGTTTGTTTG
  AGCTTAGGGATGAGATACTTATGCAAGATATTTTTGAAGTAAATTAAACATTTTTCACAT
  CTCTGGAAATTTAGAGTTCTAGACCTCTGGTTAATTTATATCTAATATGAAGAAGACACC
  TCTAATCTGGATGTTAAGAATGAAGTTCTGCTACATTATAATGTACAGAAGAGCAAAAGG
  GAGGAACACTATGGTTAACCCTCTCTTGATTAAGGGCTACTTAATGCACAGTGCATTATG
  TACACAGGTCAACCATGGTAACAATAGTTCTTAGCTTTGAAACTCCATGCAAACCATGCC
  TTTTTTTTAAGGAGCAAAAATCTGAGAAAAAAAGTGAGAGACCTCTGCCTACAAAACCTC
  AAACCAGTCACTTTTGTCAATTGCTAATACCCAGTTACTTATGATTTAAAAACAACCAAC
  AGAAAACATCCCACTGACTGTATGGCACTCTGTAGTCAAAAAAGGAAACTTCCTTATTGG
  GACTTTTCTTTCTTAGTCCAGTTGTGTTGACACATATGAACACAGACAAAGTGCTATGCG
  GAGGAAAGCAAGTGTTGGTCAGTAGTTTCATGTTTTAGGGAGTGGTTCCTGTGGAGATCA
  GAAAGTGACATTTGCTTTCGGTACTGTAATACGTGCACCAAACTGCCTCAATCCTAGGTA
  ACGAGGGCAACAGGGAGCACCTGTCTGGATTGTTTTTAAACCTCCATACTCAAGCTGTCT
  CTTCGGCAGGGAGGTGAATACTCTTGAAAGGCCAACAGCAAGTGTTTGTGGGACACAACA
  CAGATAATTTTTTCTTAAGTCGGCCAAGATGTACTTCTCTGTGTGCACACCCATGCACAC
  TCATGCACACAGATACATAGGTCTGTATGGCTGTATTTGCTGTTGATTCAGACTTTCACA
  CCATTAATGGGGAAAAGCGTGGCCACAAAAACAGATGCTAGGAAGCTTGGCTTCCTCTTC
  TTGTTGACCCTTTTTTGAACCAACATCTTTTTTATTATATTCAGAGTATGTTTTTAAGTG
  TATCTTAATATATACATTTTTTAGGACATCTTAAATCTAAACAAAAAATAAAATGAACAT
  CTCTTGAAACCTGTTAAAACAACCAGTTAAAGCCACAGATGGCTTTCAGGGCAGTAGCAG
  CAGAGGCCAGTGGACTCTGAGGACTCCTGAGGGGCGGGGCGTGTAGCCAGCCAGGTGCAT
  GCCGGGACCATGGCCCCCATACTTGGCTGCTTCCTGTGACAGTGAAATACATCCTTCAAG
  GTGGCAGCTGTTAGGGCTGAATCTTCTGGAGAAAAAGGTGCCATCTCAGGAGAATAGCTT
  TTACTCTGGTAGGAATGCTTCCGAGACACCACAAGGCAGCCTGAACACTCAGTTGCAGGG
  TCGGGCTTGCGGTGGGTGACCCAGAGCCACCAAAGTCACATCCACAACTAATGAGGGAAA
  TCTGTAAAGCCAGTTAGATAGAAGAATTTTATTTTTCTGTGGGTTTTGTGTTGTCTTTTT
  TATGTTAAAAAGAAATCCAGTTTGTGTTTTTCTATAGAAAAAGTAAAAGATCAGGTTATA
  CTTTAGGTTAGGGGTTCTATTTATTCCTGTTAGTAAATAAAATTAACAAATTTCTTTGTT
  TAACAAAAGATTAATCTTTAAACCACTAAAATACATAGACTGATTGATTATTCAACACAT
  TGGAATTGATGTCGGTCATAGTTTCCTGAAGCATTTAGTTACAACCTGAAGGAATAAAAT
  GATTTGTGGAAATGCTTAAAATAGACCTAACTGAATACAGTCTCATCTTGCCGCGCCTGG
  CTTACCTATCTGTGGAAAGCTAGGCTTCCCAGGCTGGGCTCTGCCTGTCTGGTGCCTGGA
  GGTGTGGGAGGGAAGATGAGTTATTTAACTGGTAAGCGATTTGAAACACTATTTTTATAT
  TAAAGTAAATGGCATGGAGTATAGTGCAAATTCATTTTTAAGATAGAACACAAAACTTGA
  AAGAAGTTTTATGCGTGTGACAGTGTATGGGGCTGCAGTTGGTCTCCCTGGAGGGGACTT
  CCACACCTCCTGCCTTTAGGCCATGGGTGGAAAGTGCTCAGTGAAGTACACCTGTGTGGC
  CCAGTTCTGAAAGCTTTATACAGTTGAATTTTAAGTGGGGTTGATAACACCTTGGACTGT
  TAGTGTTAAAAATCTAGTGGGTTGACCTTTAAATGCAACAGTTTTTAAAATATATTGCTG
  CATTTTATAGAATAGTAAAGGTACGATTATACTTGAGATTTTCCTCCATTTTTATTTCTT
  CGTGAACATAGAGTTTGGGGCCGAAAATGTTTTTAAAGTATGTGTTTGAGTTAAATATAA
  AGTTGGTTCACTTCAAAGCTAAAAAATTGTTAAACTTGCAGCTTGGTATTGCAGAGAAGA
  TTTTATAAGAATTTTGCTTTAGAGAATGCCACTTTGGCTGAACTACAAGTGTAGGCCACC
  ATTATAATTTATAAATACAGCATACTTCAAAACTGTTTGTTATCTCTTGTTACCATGTAT
  GTATAAATGGACCTTTTATAACCTTGTTCTCTGCTTGACAGACTCAAGAGAAACTACCCA
  GGTATTACACAAGCCAAAATGGGAGCAAGGCCTTCTCTCCAGACTATCGTAACCTGGTGC
  CTTACCAAGTTGTGCTTTTCTGTTTTCAAGTGTAAATGATGTTGAGCAGAATGTTGTACT
  TGAAAATGCTATAAGTGAGATGGTATGAAATAAATTCTGACTTATGAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021205.4 unedited
  AGCCGTACTATTTGTAATACGACTCCTATAGGGCGGCCGGCGACGCGGCGCGCCGGTACC
  GGTCCGGAATTCCCGGGATCGGCGCTCGGACCGCTGTCCTCCAACAGCGCAGGGCAGAGC
  GGCTGGCGCCGCCGGAGCGCGGAGCCACGACCCTCCCTGGCCGCCTTTGTCTACTGGCCG
  TGCGGCCCGGAACCGCCACTCTCCAGGGCCGGGGACGCGCCCGCAGCTGTCGGTGACAGC
  TCCTCCCTACCGCAACCCTCCGGGGCGGAGGGGCGGTCGGGCCGGGCCCTGCTAGCCCGC
  GACCGCAAGCCCGCGCTCGCGGATCGATGCCCCCGCAGCAGGGGGACCCCGCGTTCCCTG
  ACCGCTGCGAGGCGCCTCCGGTGCCGCCGCGTCGGGAGCGCGGTGGACGCGGGGTACGCT
  TTCCTGGGGAGCCGGCGG
• Restriction Sites: ECoRI-NOT
• ACCN: NM_021205
• ORF Size: 777 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_021205.4, NP_067028.1
• RefSeq Size: 4369
• RefSeq ORF: 777
• Locus ID: 58480
• Domains: ras, RAN, RAS, RHO, RAB
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the Rho family of GTPases. This protein can activate PAK1 and JNK1, and can induce filopodium formation and stress fiber dissolution. It may also mediate the effects of WNT1 signaling in the regulation of cell morphology, cytoskeletal organization, and cell proliferation. A non-coding transcript variant of this gene results from naturally occurring read-through transcription between this locus and the neighboring DUSP5P (dual specificity phosphatase 5 pseudogene) locus. [provided by RefSeq, Mar 2011]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the functional protein.