Kallikrein 8 (KLK8) (NM_007196) Human Untagged Clone

CAT#: SC324103

KLK8 (untagged)-Human kallikrein-related peptidase 8 (KLK8), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KLK8
• Synonyms: HNP; NP; NRPN; PRSS19; TADG14
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_007196.2 CGCCCCTCGTGATGTCAGGGGCGCAGTAGCTCCGCCCACGTGGAGCTCGGGCGGTGTAGA
  GCTCAGCCCCTTGTGGCCCCGTCCTGGGCGTGTGCTGGGTTTGAATCCTGGCGGAGACCT
  GGGGGGAAATTGAGGGAGGGTCTGGATACCTTTAGAGCCAATGCAACGGATGATTTTTCA
  GTAAACGCGGGAAACCTCACCTTCTTTCTGCCTGAGCTGTGAGATGAGTGGAGAGCAAAC
  GGGTGGGCGGTGAAGGGCAGATGAGGGAACCGGTACCGCCTTGCAACTCCCCCTTAAACC
  CCTATGTTCCAGTTCCCAGAAGCTCCCCAGGCTCTAGTGCAGGAGGAGAAGGAGGAGGAG
  CAGGAGGTGGAGATTCCCAGTTAAAAGGCTCCAGAATCGTGTACCAGGCAGAGAACTGAA
  GTACTGGGGCCTCCTCCACTGGGTCCGAATCAGTAGGTGACCCCGCCCCTGGATTCTGGA
  AGACCTCACCATGGGACGCCCCCGACCTCGTGCGGCCAAGACGTGGATGTTCCTGCTCTT
  GCTGGGGGGAGCCTGGGCAGGACACTCCAGGGCACAGGAGGACAAGGTGCTGGGGGGTCA
  TGAGTGCCAACCCCATTCGCAGCCTTGGCAGGCGGCCTTGTTCCAGGGCCAGCAACTACT
  CTGTGGCGGTGTCCTTGTAGGTGGCAACTGGGTCCTTACAGCTGCCCACTGTAAAAAACC
  GAAATACACAGTACGCCTGGGAGACCACAGCCTACAGAATAAAGATGGCCCAGAGCAAGA
  AATACCTGTGGTTCAGTCCATCCCACACCCCTGCTACAACAGCAGCGATGTGGAGGACCA
  CAACCATGATCTGATGCTTCTTCAACTGCGTGACCAGGCATCCCTGGGGTCCAAAGTGAA
  GCCCATCAGCCTGGCAGATCATTGCACCCAGCCTGGCCAGAAGTGCACCGTCTCAGGCTG
  GGGCACTGTCACCAGTCCCCGAGAGAATTTTCCTGACACTCTCAACTGTGCAGAAGTAAA
  AATCTTTCCCCAGAAGAAGTGTGAGGATGCTTACCCGGGGCAGATCACAGATGTCATGGT
  CTGTGCAGGCAGCAGCAAAGGGGCTGACACGTGCCAGGGCGATTCTGGAGGCCCCCTGGT
  GTGTGATGGTGCACTCCAGGGCATCACATCCTGGGGCTCAGACCCCTGTGGGAGGTCCGA
  CAAACCTGGCGTCTATACCAACATCTGCCGCTACCTGGACTGGATCAAGAAGATCATAGG
  CAGCAAGGGCTGATTCTAGGATAAGCACTAGATCTCCCTTAATAAACTCACAACTCTCAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007196.2 unedited
  GGCACTTTGTATACGACTCCTATAGGGCGGCCGGCGACTCGCGGCGCGCCGGTACCGGTC
  CGGAATTCCCGGGATCGCCCCTCGTGATGTCAGGGGCGCAGTAGCTCCGCCCACGTGGAG
  CTCGGGCGGTGTAGAGCTCAGCCCCTTGTGGCCCCGTCCTGGGCGTGTGCTGGGTTTGAA
  TCCTGGCGGAGACCTGGGGGGAAATTGAGGGAGGGTCTGGATACCTTTAGAGCCAATGCA
  ACGGATGATTTTTCAGTAAACGCGGGAAACCTCACCTTCTTTCTGCCTGAGCTGTGAGAT
  GAGTGGAGAGCAAACGGGTGGGCGGTGAAGGGCAGATGAGGGAACCGGTACCGCCTTGCA
  ACTCCCCCTTAAACCCCTATGTTCCAGTTCCCAGAAGCTCCCCAGGCTCTAGTGCAGGAG
  GAGAAGGAGGAGGAGCAGGAGGTGGAGATTCCCAGTTAAAAGGCTCCAGAATCGTGTACC
  AGGCAGAGAACTGAAGTACTGGGGCCTCCTCCACTGGGTCCGAATCAGTAGGTGACCCCG
  CCCCTGGATTCTGGAAGACCTCACCATGGGACGCCCCCGACCTCGTGCGGCCAAGACGTG
  GATGTTCCTGCTCTTGCTGGGGGGAGCCTGGGCAGGACACTCCAGGGCACAGGAGGACAA
  GGTGCTGGGGGGTCATGAGTGCCAACCCCATTCGCAGCCTTGGCAGGCGGCCTTGTTCCA
  GGGCCAGCAACTACTCTGTGGCGGTGTCCTTGTAGTGGCAACTGGGTCCTTACAGCTGCC
  CCACTGTAAAAAACCGAAATACACAGTACGCCTGGGAGACCACAGCCTACAGAATAAAGA
  TGGCCCAGAGCAGAAATACCTGTGGTCAGTCATCCACACCCTGCTACACAGCAGCGATGT
  GGAGGACCACACCATGATTCTGATGCTTCTTCAACTGGCGTGGACCAGGCAATCCCTGGG
  GTTCCA
• Restriction Sites: ECoRI-NOT
• ACCN: NM_007196
• ORF Size: 783 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_007196.2, NP_009127.1
• RefSeq Size: 1013
• RefSeq ORF: 783
• Locus ID: 11202
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Gene Summary: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. The encoded protein may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (1, also known as T1) uses an alternate splice site in the 5' coding region, compared to variant 2. It encodes isoform 1, which is shorter than isoform 2.