PACRG (NM_001080379) Human Untagged Clone

CAT#: SC324110

PACRG (untagged)-Human PARK2 co-regulated (PACRG), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PACRG
• Synonyms: GLUP; HAK005771; PACRG2.1; PARK2CRG
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001080379.1 GGAGTTTCTGTGGAGCCAGCCACCCTCACCAGGTGCCTTCCATTAGAGTTTAATGCTTTG
  CTGCGGTTTCCTGAAAGAGCCCCACAGAGAGTGGGTCTCGATGGGTCCTGAACCGCACCA
  CAACCGGCCAGTGAGACCTCCTGCTCACATCCGTAAAGCCCACTGATTCTTTTACTACAC
  TTTTTATGAGAACAAGACATTTTCTAGGAAGATGGTGGCAGAAAAAGAGACCCTGAGCTT
  AAACAAATGCCCAGACAAGATGCCGAAGAGGACCAAGCTGCTGGCACAACAGCCGCTCCC
  GGTGCACCAGCCTCACTCTCTGGTTTCTGAGGGTTTCACAGTCAAAGCCATGATGAAAAA
  CTCAGTCGTGAGAGGCCCTCCAGCTGCAGGGGCATTTAAAGAAAGACCAACCAAGCCCAC
  AGCATTTCGAAAATTCTATGAGCGAGGTGACTTCCCAATTGCCCTTGAGCATGATTCGAA
  AGGAAACAAAATCGCCTGGAAGGTAGAAATTGAGAAGCTGGATTACCATCATTATCTGCC
  TCTGTTTTTTGATGGGCTTTGTGAAATGACATTTCCCTATGAGTTTTTTGCTCGGCAAGG
  AATCCACGACATGCTGGAACACGGTGGGAACAAGATCCTACCTGTCCTTCCACAGCTCAT
  TATCCCGATAAAAAATGCCTTGAACCTCCGAAACCGACAGGTCATCTGTGTCACTCTCAA
  GGTCCTCCAGCATCTGGTTGTGTCAGCTGAGATGGTGGGCAAGGCCTTGGTGCCTTATTA
  CCGTCAAATCCTCCCTGTCCTGAACATCTTTAAGAATATGAATGTGAACTCCGGAGACGG
  CATTGACTACAGCCAGCAGAAGAGGGAGAACATTGGGGACTTGATCCAGGAGACACTGGA
  GGCCTTCGAGCGCTACGGAGGAGAAAATGCCTTTATCAACATTAAGTACGTGGTCCCAAC
  CTACGAGTCTTGCTTGCTAAACTAACAGTGGCAGCAGCTGGGACTTGAAACCTCCCGTTG
  GTGTTGGGATCATCTGTCTCTGTTGCTTTTAGCATCTCATTCCTTGTGACTTCCACAGCT
  TTCTTTTCTACAGCTGCTAAAATAGTGGCTTATGGGCCATTGGACTGTTAGCCCTATTGA
  GAGCAAGGCTTTCCAATACATAAATAGTGTCTGTTTCTTAGATTACAATAGTGTACTGTG
  CTTATTTGTTCTAAGAGAAGAATTGCTTCTTTATACAGCTCCGACAGAAGCAGGAGTCCG
  AGTTAAACCTTCAGTTGTATAGACAATAAACTATAATTTTCATATGCAATTCAGCAATTG
  CTGTTCTGTGTGTGCCTGCCCTGGGGGTGATGTCAGAGGTTGTAAGGGAAGAGTTTATGC
  TGACTGCTTACTAGGTGTTTGTCATGGAAGAGAAGCATGGGTTCAGCAGTGCCTCTCTAG
  CAGCTGTGCGGAATAATGTGCTTTGACATTCAATAAAACTGTTGAATCTAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001080379.1 unedited
  TACACTGCTGTATACGACTCCTATAGGGCGGCCGGCGATCGCGGCGCGCCGGTACCGGTC
  CGGAATTCCCGGGATGGAGTTTCTGTGGAGCCAGCCACCCTCACCAGGTGCCTTCCATTA
  GAGTTTAATGCTTTGCTGCGGTTTCCTGAAAGAGCCCCACAGAGAGTGGGTCTCGATGGG
  TCCTGAACCGCACCACAACCGGCCAGTGAGACCTCCTGCTCACATCCGTAAAGCCCACTG
  ATTCTTTTACTACACTTTTTATGAGAACAAGACATTTTCTAGGAAGATGGTGGCAGAAAA
  AGAGACCCTGAGCTTAAACAAATGCCCAGACAAGATGCCGAAGAGGACCAAGCTGCTGGC
  ACAACAGCCGCTCCCGGTGCACCAGCCTCACTCTCTGGTTTCTGAGGGTTTCACAGTCAA
  AGCCATGATGAAAAACTCAGTCGTGAGAGGCCCTCCAGCTGCAGGGGCATTTAAAGAAAG
  ACCAACCAAGCCCACAGCATTTCGAAAATTCTATGAGCGAGGTGACTTCCCCAATTGCCC
  TTGAACATGATTCGAAAGGAAACAAAATCGCCTGGAAGGTAAAAATTGGAAAGC
• Restriction Sites: ECoRI-NOT
• ACCN: NM_001080379
• ORF Size: 774 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001080379.1, NP_001073848.1
• RefSeq Size: 1627
• RefSeq ORF: 774
• Locus ID: 135138
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a protein that is conserved across metazoans. In vertebrates, this gene is linked in a head-to-head arrangement with the adjacent parkin gene, which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones, including heat shock proteins 70 and 90, and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients, and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (3) lacks an exon at its 5' end and an in-frame internal exon, compared to variant 1. These differences produce a unique 5' UTR and a protein (isoform 2) that is shorter than isoform 1. Both variants 2 and 3 encode the same isoform.