HRPT2 (CDC73) (NM_024529) Human Untagged Clone

CAT#: SC324236

CDC73 (untagged)-Human cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) (CDC73)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDC73
• Synonyms: C1orf28; FIHP; HPTJT; HRPT1; HRPT2; HYX
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_024529.3 GGCGAGGCGACAAGAGAAGAAGGAGGCAGGCGCGGCGGCAGCGGCGGCGCCCCGAGCCGG
  CGGAGGCGAGGGGGGGGAAGATGGCGGACGTGCTTAGCGTCCTGCGACAGTACAACATCC
  AGAAGAAGGAGATTGTGGTGAAGGGAGACGAAGTGATCTTCGGGGAGTTCTCCTGGCCCA
  AGAATGTGAAGACCAACTATGTTGTTTGGGGGACTGGAAAGGAAGGCCAACCCAGAGAGT
  ACTACACATTGGATTCCATTTTATTTCTACTTAATAACGTGCACCTTTCTCATCCTGTTT
  ATGTCCGACGTGCAGCTACTGAAAATATTCCTGTGGTTAGAAGACCTGATCGAAAAGATC
  TACTTGGATATCTCAATGGTGAAGCGTCAACATCGGCAAGTATAGACAGAAGCGCTCCCT
  TAGAAATAGGTCTTCAGCGATCTACTCAAGTCAAACGAGCTGCAGATGAAGTTTTAGCAG
  AAGCAAAGAAACCACGAATTGAGGATGAAGAGTGTGTGCGCCTTGATAAAGAGAGATTGG
  CTGCCCGTTTGGAGGGTCACAAAGAAGGGATTGTACAGACTGAACAGATTAGGTCTTTGT
  CTGAAGCTATGTCAGTGGAAAAAATTGCTGCAATCAAAGCCAAAATTATGGCTAAGAAAA
  GATCTACTATCAAGACTGATCTAGATGATGACATAACTGCCCTTAAACAGAGGAGTTTTG
  TGGATGCTGAGGTAGATGTGACCCGAGATATTGTCAGCAGAGAGAGAGTATGGAGGACAC
  GAACAACTATCTTACAAAGCACAGGAAAGAATTTTTCCAAGAACATTTTTGCAATTCTTC
  AATCTGTAAAAGCCAGAGAAGAAGGGCGTGCACCTGAACAGCGACCTGCCCCAAATGCAG
  CACCTGTGGATCCCACTTTGCGCACCAAACAGCCTATCCCAGCTGCCTATAACAGATACG
  ATCAGGAAAGATTCAAAGGAAAAGAAGAAACGGAAGGCTTCAAAATTGACACTATGGGAA
  CCTACCATGGTATGACACTGAAATCTGTAACGGAGGGTGCATCTGCCCGGAAGACTCAGA
  CTCCTGCAGCCCAGCCAGTACCAAGACCAGTTTCTCAAGCAAGACCTCCCCCAAATCAGA
  AGAAAGGATCTCGAACACCCATTATCATAATTCCTGCAGCTACCACCTCTTTAATAACCA
  TGCTTAATGCAAAAGACCTTCTACAGGACCTGAAATTTGTCCCATCAGATGAAAAGAAGA
  AACAAGGTTGTCAACGAGAAAATGAAACTCTAATACAAAGAAGAAAAGACCAGATGCAAC
  CAGGGGGCACTGCAATTAGTGTTACAGTACCTTATAGAGTAGTAGACCAGCCCCTTAAAC
  TTATGCCTCAAGACTGGGACCGCGTTGTAGCCGTTTTTGTGCAGGGTCCTGCATGGCAGT
  TCAAAGGTTGGCCATGGCTTTTGCCTGATGGATCACCAGTTGATATATTTGCTAAAATTA
  AAGCCTTCCATCTGAAGTATGATGAAGTTCGTCTGGATCCAAATGTTCAGAAATGGGATG
  TAACAGTATTAGAACTCAGCTATCACAAACGTCATTTGGATAGACCAGTGTTCTTACGGT
  TTTGGGAAACATTGGACAGGTACATGGTAAAGCATAAATCGCACTTGAGATTCTGAATTA
  TTTGGCTCCTCCATTTCTGGAAATTGAGACTCAAGCTTTATGAATTTATCAAGAACTTAA
  AAATGAAGAAGGTCACAGATTGATCTTTTATAAGACCTTATTTGATGCTTTGTGCTTCAA
  GGAGATGATACCTGTCATCCATATAAGCAAACTTTTTGGCTTACAACTATTTTTTTAATA
  TTAGCCTTCTAGTCTGTAATGGAAATTGTATATTTTGATAGAAGTTTTTTCTCCATTGGT
  TAAATTAGCATTACTTAAAATTTGTTTCTTTAGAAAATAAATGCAGGTTATAAATGTGTG
  TATATTTAGAGATTATAAGGCTCTCTGAGCCATCTTCTGATTTTTCATTGCTCTATAATT
  CTTTTTACTGAAAATACTATGTTATGAATGGTATTAAATTTTAGTCTCTGGAACATCCAA
  AACCAAGCAAAGGGATGTGACTATTTTGAATGAATCAGAATGTCAACTTGTATGTACACT
  ATATCTACACTTACTCATTATTTAAAAAGAATAATGAAAAATCTAGATCAATTAAAAAAA
  AAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_024529.3 unedited
  TACAACGCTGTATACGACTCCTATAGGGCGGCCGGCGTACTCGCGGCGCGCCGGTACCGG
  TCCGGAATTCCCGGGATATCGTCGACCCACGCGTCCGGGCGAGGCGACAAGAGAAGAAGG
  AGGCAGGCGCGGCGGCAGCGGCGGCGCCCCGAGCCGGCGGAGGCGAGGGGGGGGAAGATG
  GCGGACGTGCTTAGCGTCCTGCGACAGTACAACATCCAGAAGAAGGAGATTGTGGTGAAG
  GGAGACGAAGTGATCTTCGGGGAGTTCTCCTGGCCCAAGAATGTGAAGACCAACTATGTT
  GTTTGGGGGACTGCAAAGGAAGGCCAACCCAAAGAAACAACGGATTGGGGTGTGTGGTTT
  ATCTCAACCTAACAACGCCCCAAGATAACATCCTGTG
• Restriction Sites: ECoRI-NOT
• ACCN: NM_024529
• ORF Size: 1596 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_024529.3, NP_078805.3
• RefSeq Size: 2980
• RefSeq ORF: 1596
• Locus ID: 79577
• Domains: Cdc73
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009]