NSP3 (SH2D3C) (NM_005489) Human Untagged Clone

CAT#: SC324275

SH2D3C (untagged)-Human SH2 domain containing 3C (SH2D3C), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SH2D3C
• Synonyms: CHAT; NSP3; PRO34088; SHEP1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_005489.1 GCGGGGGAAGCATGACTGCTGTGGGCCGAAGGTGCCCCGCGCTGGGGTCCCGAGGGGCTG
  CTGGAGAGCCAGAGGCTGGCAGCGACTATGTGAAGTTCTCCAAGGAGAAGTACATCCTGG
  ACTCATCGCCAGAGAAACTCCACAAGGAATTGGAGGAGGAGCTCAAACTCAGCAGCACGG
  ATCTCCGCAGCCATGCCTGGTACCATGGCCGCATCCCCCGAGAGGTCTCGGAGACCTTGG
  TACAACGCAACGGCGACTTCCTCATCCGGGACTCACTCACCAGCCTGGGCGACTATGTGC
  TCACGTGCCGCTGGCGCAACCAGGCCTTGCACTTCAAGATCAACAAGGTGGTGGTGAAGG
  CAGGCGAGAGCTACACACACATCCAGTACCTGTTTGAGCAGGAGAGCTTTGACCACGTGC
  CCGCCCTCGTGCGCTATCATGTGGGCAGCCGCAAGGCTGTGTCAGAGCAGAGTGGTGCCA
  TCATCTACTGCCCGGTGAACCGCACCTTCCCACTGCGCTACCTCGAGGCCAGCTATGGCC
  TGGGACAGGGGAGTAGCAAGCCTGCTAGCCCCGTCAGCCCCTCAGGCCCCAAGGGCAGCC
  ACATGAAGCGGCGCAGCGTCACCATGACCGATGGGCTCACTGCTGACAAGGTCACCCGCA
  GCGATGGCTGCCCCACCAGTACGTCGCTGCCCCGCCCTCGGGACTCCATCCGCAGCTGTG
  CCCTCAGCATGGACCAGATCCCAGACCTGCACTCACCCATGTCGCCCATCTCCGAGAGCC
  CTAGCTCCCCTGCCTACAGCACTGTAACCCGTGTCCATGCCGCCCCTGCAGCCCCTTCTG
  CCACAGCATTGCCTGCCTCCCCTGTCGCCCGCCGTTCCAGTGAGCCCCAGCTGTGTCCCG
  GAAGTGCCCCAAAGACCCATGGGGAGTCAGACAAGGGCCCCCACACCAGCCCCTCCCACA
  CCCTTGGCAAGGCCTCCCCGTCACCATCACTCAGCAGCTACAGTGACCCGGACTCTGGCC
  ACTACTGCCAGCTCCAGCCTCCCGTGCGTGGCAGCCGAGAGTGGGCAGCGACTGAGACCT
  CCAGCCAGCAGGCCAGGAGCTATGGGGAGAGGCTAAAGGAACTGTCAGAAAATGGGGCCC
  CTGAAGGGGACTGGGGCAAGACCTTCACAGTCCCCATCGTGGAAGTCACTTCTTCCTTCA
  ACCCGGCCACCTTCCAGTCACTACTGATCCCCAGGGATAACCGGCCACTGGAGGTGGGCC
  TTCTGCGCAAGGTCAAGGAGCTGCTGGCAGAAGTGGATGCCCGGACGCTGGCCCGGCATG
  TCACCAAGGTGGACTGCCTGGTTGCTAGGATACTGGGCGTTACCAAGGAGATGCAGACCC
  TAATGGGAGTCCGCTGGGGCATGGAACTGCTCACCCTCCCCCATGGCCGGCAGCTACGCC
  TAGACCTGCTGGAAAGGTTCCACACCATGTCCATCATGCTGGCCGTGGACATCCTGGGCT
  GCACCGGCTCTGCGGAGGAGCGGGCAGCGCTGCTGCACAAGACCATTCAGCTGGCGGCCG
  AGCTGCGGGGGACTATGGGCAACATGTTCAGCTTCGCGGCGGTCATGGGTGCCCTGGACA
  TGGCTCAGATTTCTCGGCTGGAGCAGACATGGGTGACCCTGCGGCAGCGACACACAGAGG
  GTGCCATCCTGTACGAGAAGAAGCTCAAGCCTTTTCTCAAGAGCCTCAACGAGGGCAAAG
  AAGGCCCGCCGCTGAGCAACACCACGTTTCCTCATGTGCTGCCCCTCATCACCCTGCTGG
  AGTGTGACTCGGCCCCACCAGAGGGCCCTGAGCCCTGGGGCAGCACGGAGCACGGCGTGG
  AGGTGGTGCTGGCTCACCTGGAGGCCGCCCGCACAGTGGCACACCACGGAGGCCTGTACC
  ACACCAATGCTGAAGTCAAGCTGCAGGGGTTCCAGGCCCGGCCGGAGCTCCTGGAGGTGT
  TCAGCACGGAGTTCCAGATGCGCCTTCTCTGGGGCAGTCAGGGTGCCAGCAGCAGCCAGG
  CCCGGCGCTATGAGAAGTTCGACAAGGTCCTCACTGCCCTGTCCCACAAGCTGGAACCTG
  CTGTCCGCTCCAGCGAGCTGTGACCCCAGGGACATTTCCCCTCTGCAGCTGCGGACAGCG
  TCAGGGGCAGAGGGGCACACAACTTTCCCCAGAGCACCCCAAGGACACTGTGATCAACCC
  GAGAATGTTCTGGGTTCAACTCAAGCATCTCCCTTGCACCTCCAGGGTCCTGCGTGGACT
  CTGGGTTCCATCCCACCTGCTACATGCTCACCAGGTCTCCATTGAGGAAGAACAGGAACG
  CCGGTTCCCCCACCAGCTTTTGCTGCTCCCCTTCCTGCTGGGGTTCCCTGTTTTCGAGCC
  ATGGGAGGCAGGCTGCTCACGCCTCCTCACTCTCTGTCTGTCCCTCACCAACACCAAGGC
  CTCCATCTCACTGTAAATAAGTCTCTGTTCTGTAAATAGATGTACAGAAGCCATGTTATT
  TCTTTCATATAATAAACTTTTATGACTCTTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005489.1 unedited
  GACAATGCATGCACGCCCCTCCCGCATGTCTTCTGACCTCCATAGAAGACACCGGGACCG
  ACTCCAGCCTCCGGACTCTAGCCTAGGCCGCGGGACGGATAACAATCTCACACAGGAAAC
  AGCTATGACCATTAGGCCTATTTAGGTGACACTATAGAACAAGTTTGTACAAAAAAGCAG
  GCTGGTACCGGTCCGGAATTCCCGGGATAGCGGGGGAAGCATGACTGCTGTGGGCCGAAG
  GTGCCCCGCGCTGGGGTCCCGAGGGGCTGCTGGAGAGCCAGAGGCTGGCAGCGACTATGT
  GAAGTTCTCCAAGGAGAAGTACATCCTGGACTCATCGCCAGAGAAACTCCACAAGGAATT
  GGAGGAGGAGCTCAAACTCAGCAGCACGGATCTCCGCAGCCATGCCTGGTACCATGGCCG
  CATCCCCCGAGAGGTCTCGGAGACCTTGGTACAACGCAACGGCGACTTCCTCATCCGGGA
  CTCACTCACCAGCCTGGGCGACTATGTGCTCACGTGCCGCTGGCGCAACCAGGCCTTGCA
  CTTCAAGATACACAAGGTGGTGGGTGAAACGCACGCGAGAGCTACACACACATTCCCGTA
  CTTGTGTTGAGCACGGACAGCTTTGACAACATGCCCCGCCCTCTGGGCTGAGCCTTGAGG
  AGCTAAGTGCAAGTATGTAGCGAAATA
• Restriction Sites: Please inquire
• ACCN: NM_005489
• ORF Size: 2112 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_005489.1, NP_005480.1
• RefSeq Size: 2164
• RefSeq ORF: 2112
• Locus ID: 10044
• Domains: SH2, RasGEF
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  Transcript Variant: This variant (2) includes alternate exons in the 5' coding region, compared to variant 1. It encodes isoform b, which is shorter and has a distinct N-terminus compared to isoform a.