FBXL2 (NM_012157) Human Untagged Clone

CAT#: SC324282

FBXL2 (untagged)-Human F-box and leucine-rich repeat protein 2 (FBXL2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBXL2
• Synonyms: FBL2; FBL3
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_012157.2 CGCGGCTCTTCGGCCATGGTTTTCTCAAACAATGATGAAGGCCTTATTAACAAAAAGTTA
  CCCAAAGAACTTCTGTTAAGAATATTTTCCTTCTTGGATATAGTAACTTTGTGCCGATGT
  GCACAGATTTCCAAGGCTTGGAACATCTTAGCCCTGGATGGAAGCAACTGGCAAAGAATA
  GATCTTTTTAACTTTCAAACAGATGTAGAGGGTCGAGTGGTGGAAAATATCTCGAAGCGA
  TGCGGTGGATTCCTGAGGAAGCTCAGCTTGCGAGGCTGCATTGGTGTTGGGGATTCCTCC
  TTGAAGACCTTTGCACAGAACTGCCGAAACATTGAACATTTGAACCTCAATGGATGCACA
  AAAATCACTGACAGCACGTGTTATAGCCTTAGCAGATTCTGTTCCAAGCTGAAACATCTG
  GATCTGACCTCCTGTGTGTCTATTACAAACAGCTCCTTGAAGGGGATCAGTGAGGGCTGC
  CGAAACCTGGAGTACCTGAACCTCTCTTGGTGTGATCAGATCACGAAGGATGGCATCGAG
  GCACTGGTGCGAGGTTGTCGAGGCCTGAAAGCCCTGCTCCTGAGGGGCTGCACACAGTTA
  GAAGATGAAGCTCTGAAACACATTCAGAATTACTGCCATGAGCTTGTGAGCCTCAACTTG
  CAGTCCTGCTCACGTATCACGGATGAAGGTGTGGTGCAGATATGCAGGGGCTGTCACCGG
  CTACAGGCTCTCTGCCTTTCGGGTTGCAGCAACCTCACAGATGCCTCTCTTACAGCCCTG
  GGTTTGAACTGTCCGCGACTGCAAATTTTGGAGGCTGCCCGATGCTCCCATTTGACTGAC
  GCAGGTTTTACACTTTTAGCTCGGAATTGCCACGAATTGGAGAAGATGGATCTTGAAGAA
  TGCATCCTGATAACCGACAGCACACTCATCCAGCTCTCCATTCACTGTCCTAAACTGCAA
  GCCCTGAGCCTGTCCCACTGTGAACTCATCACAGATGATGGGATCCTGCACCTGAGCAAC
  AGTACCTGTGGCCATGAGAGGCTGCGGGTACTGGAGTTGGACAACTGCCTCCTCATCACT
  GATGTGGCCCTGGAACACCTAGAGAACTGCCGAGGCCTGGAGCGCCTCGAGCTGTACGAC
  TGCCAGCAGGTTACCCGTGCAGGCATCAAGCGGATGCGGGCTCAGCTCCCTCATGTCAAA
  GTCCACGCCTACTTTGCTCCCGTCACCCCACCGACAGCAGTGGCAGGAAGTGGACAGCGA
  CTGTGCAGGTGCTGTGTCATTCTCTGACAGCAGCTGCCTGGGCCCAAGGGGTGATGAGGC
  ATCCTTTCCTCTAGAAGACCTGAGTCTTCCTGACCGACTCCACCATCACCCAATCTGTTG
  ATTCTCCATTGGGAAAGGCATTTACAGGTAAAAGACTTCTGTATGGATTGCAGTTACTCT
  GGTGATAGTTTTCACCTTTATTCTGCTGTGAAACAATCAAATCAAAGCCTTGTGTCAGTT
  AACACATGACAAGTGGTCTCAATGCAGCTAGGACCATGCCAGAAACCTGGATCTCTTAAG
  AGATTGGTACCTACCTAGGTACGAAAGTTCTACCCTTGGCATACTCAGCATTCCTCAAAA
  AGACCATCAGTGTTAGCACAAACTGAGCAGAAAAAATAAGCTGTTGATTTTCTACCTGAT
  ACTTAAGCCAGTGGCCTACTTTAATTCACAATTCCATTTTGATTAGCAGGACTTTTCCAC
  TTTGAAGATAAATAGCAACTTTATCAAAGTGACTGTACTGCAAATTAATTCATAATGCCT
  GATAGTTTTATATATAGAGACTTATGTGGAAGGCATGTTAATAGGTTTCCATGAGACACC
  AAAGAAAAGAGGACTCTATACTGGGTGGAGCAGGGTCTTCACCTTTTTGTTTCTGTCAAC
  TGTCATATACACCTCCAGGGACCAAAAACAAAAGCAGCTCGGAGTCTGTGTTGCCTGATT
  GGAAAGTAGAAGCTCTGGTGTATGCTACAGCACATAACACATTTTTACTAAAGGAAAAAA
  GCTAATTATGTCCATGCCTCTCGTAAAACTGGGGGGAACCTTAAAGAGAAAGAACTAAGG
  CTTAAGTTATCTGTAGTATAATCAATTAGAAGTAATGAATGGATGCATGTAAAATGGATG
  TGATTTTTTTTCAAGCTTATTTTGAAATCTTAAAAATCAGGTTACACCATAGCTACTCAA
  AAGTTTTACACACTTAAAACTCAGATCAGTAAGTGTTGGTACCTTTTAGACTCATAAAAT
  TGAATAAACCATTGCAATGCTTTAAAAAAAAAAAAAAAAAAAAAAAAAAA
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012157.2 unedited
  GTACTTAGCCTGCACGCCTCCCGCTGTTTTGACCTCCATAGAAGACACCGGGACCGATCC
  AGCCTCCGGACTCTAGCCTAGGCCGCGGGACGGATAACAATTTCACACAGGAAACAGCTA
  TGACCATTAGGCCTATTTAGGTGACACTATAGAACAAGTTTGTACAAAAAAGCAGGCTGG
  TACCGGTCCGGAATTCCCGGGATCGCGGCTCTTCGGCCATGGTTTTCTCAAACAATGATG
  AAGGCCTTATTAACAAAAAGTTACCCAAAGAACTTCTGTTAAGAATATTTTCCTTCTTGG
  ATATAGTAACTTTGTGCCGATGTGCACAGATTTCCAAGGCTTGGAACATCTTAGCCCTGG
  ATGGAAGCAACTGGCAAAGAATAGATCTTTTTAACTTTCAAACAGATGTAGAGGGTCGAG
  TGGTGGAAAATATCTCGAAGCGATGCGGTGGATTCCTGAGGAAGCTCAGCTTGCGAGGCT
  GCATTGGTGTTGGGGATTCCTCCTTGAAGACCTTTGCACAGAACTGCCGAAACATTGAAC
  ATTTGAACCTCAATGGATGCACAAAAATCACTGACAGCACGTGTTATAGCCTTAGCAGAT
  TCTGTTCCAAGCTGAAACATCTGGATCTGACCTCCTGTGTGTCTATTACAAACAGCTCCT
  TGAAAGGGATCAGTGAGGGCTGCCGAAACCTGAGTACCTGAACCTCTCTTGGTGTGATCA
  GATCACGAAGGATGGCATCGAGGCACTGGTGCGAGGTTGTCGAGGCCTGAAAGCCCTGCT
  CCTGAGGGCTGCACACAGTTAGAGATGAAGCTCTGAAAAACATTCAGATTACTGCCATGA
  GCTTGTGAGCCTCACTTGCAGTCCTGCTCACGTATCACGGATGAAGGTGGTGGTGCAAGA
  TATTGCAGGGGCTTGTCACCGGGCTAACAGGGCCTCCTCTGCC
• Restriction Sites: Please inquire
• ACCN: NM_012157
• ORF Size: 1272 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_012157.2, NP_036289.2
• RefSeq Size: 2378
• RefSeq ORF: 1272
• Locus ID: 25827
• Domains: LRR, F-box, LRR_CC
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 12 tandem leucine-rich repeats. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
  Transcript Variant: This variant (1) encodes isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.