PIAS3 (NM_006099) Human Untagged Clone

CAT#: SC324304

PIAS3 (untagged)-Human protein inhibitor of activated STAT, 3 (PIAS3)


  "NM_006099" in other vectors (7)

Reconstitution Protocol

USD 310.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PIAS3
Synonyms ZMIZ5
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_006099.3 CTGGGCCTGAGCTCCGGCTCCGGCTGGGGCGCCTGCGATGTCTCAAGATGGCGGAGCTGG
GCGAATTAAAGCACATGGTGATGAGTTTCCGGGTGTCTGAGCTCCAGGTGCTTCTTGGCT
TTGCTGGCCGGAACAAGAGTGGACGGAAGCACGAGCTCCTGGCCAAGGCTCTGCACCTCC
TGAAGTCCAGCTGTGCCCCTAGTGTCCAGATGAAGATCAAAGAGCTTTACCGACGACGCT
TTCCCCGGAAGACCCTGGGGCCCTCTGATCTCTCCCTTCTCTCTTTGCCCCCTGGCACCT
CTCCTGTAGGCTCCCCTGGTCCTCTAGCTCCCATTCCCCCAACGCTGTTGGCCCCTGGCA
CCCTGCTGGGCCCCAAGCGTGAGGTGGACATGCACCCCCCTCTGCCCCAGCCTGTGCACC
CTGATGTCACCATGAAACCATTGCCCTTCTATGAAGTCTATGGGGAGCTCATCCGGCCCA
CCACCCTTGCATCCACTTCTAGCCAGCGGTTTGAGGAAGCGCACTTTACCTTTGCCCTCA
CACCCCAGCAAGTGCAGCAGATTCTTACATCCAGAGAGGTTCTGCCAGGAGCCAAATGTG
ATTATACCATACAGGTGCAGCTAAGGTTCTGTCTCTGTGAGACCAGCTGCCCCCAGGAAG
ATTATTTTCCCCCCAACCTCTTTGTCAAGGTCAATGGGAAACTGTGCCCCCTGCCGGGTT
ACCTTCCCCCAACCAAGAATGGGGCCGAGCCCAAGAGGCCCAGCCGCCCCATCAACATCA
CACCCCTGGCTCGACTCTCAGCCACTGTTCCCAACACCATTGTGGTCAATTGGTCATCTG
AGTTCGGACGGAATTACTCCTTGTCTGTGTACCTGGTGAGGCAGTTGACTGCAGGAACCC
TTCTACAAAAACTCAGAGCAAAGGGTATCCGGAACCCAGACCACTCGCGGGCACTGATCA
AGGAGAAATTGACTGCTGACCCTGACAGTGAGGTGGCCACTACAAGTCTCCGGGTGTCAC
TCATGTGCCCGCTAGGGAAGATGCGCCTGACTGTCCCTTGTCGTGCCCTCACCTGCGCCC
ACCTGCAGAGCTTCGATGCTGCCCTTTATCTACAGATGAATGAGAAGAAGCCTACATGGA
CATGTCCTGTGTGTGACAAGAAGGCTCCCTATGAATCTCTTATCATTGATGGTTTATTTA
TGGAGATTCTTAGTTCCTGTTCAGATTGTGATGAGATCCAATTCATGGAAGATGGATCCT
GGTGCCCAATGAAACCCAAGAAGGAGGCATCTGAGGTTTGCCCCCCGCCAGGGTATGGGC
TGGATGGCCTCCAGTACAGCCCAGTCCAGGGGGGAGATCCATCAGAGAATAAGAAGAAGG
TCGAAGTTATTGACTTGACAATAGAAAGCTCATCAGATGAGGAGGATCTGCCCCCTACCA
AGAAGCACTGTTCTGTCACCTCAGCTGCCATCCCGGCCCTACCTGGAAGCAAAGGAGTCC
TGACATCTGGCCACCAGCCATCCTCGGTGCTAAGGAGCCCTGCTATGGGCACGTTGGGTG
GGGATTTCCTGTCCAGTCTCCCACTACATGAGTACCCACCTGCCTTCCCACTGGGAGCCG
ACATCCAAGGTTTAGATTTATTTTCATTTCTTCAGACAGAGAGTCAGCACTATGGCCCCT
CTGTCATCACCTCACTAGATGAACAGGATGCCCTTGGCCACTTCTTCCAGTACCGAGGGA
CCCCTTCTCACTTTCTGGGCCCACTGGCCCCCACGCTGGGGAGCTCCCACTGCAGCGCCA
CTCCGGCGCCCCCTCCTGGCCGTGTCAGCAGCATTGTGGCCCCTGGGGGGGCCTTGAGGG
AGGGGCATGGAGGACCCCTGCCCTCAGGTCCCTCTTTGACTGGCTGTCGGTCAGACATCA
TTTCCCTGGACTGAGTTCCCTGGATTATGGAAACTTCGCTGTCCCCCAACACTGAGCAAG
TATGCTGTGGAGTCCCAACCCCAGCTACTCTGATCCCTCTGGGGGCTCTGGCCAAGGGCC
AGACAGACCTTCACAGATGCCTACTTTTGGCCTCATCTCTGCCTGACAAGGCCAGCACCC
AAAGGGTTAATATTTAACCTCTTTTTAAGGACACTGGGGTCTGTTTCTGGAAATGTTCTT
TAGATGGTGGCACATTCCTTTGGGTATGTTAACCTAGGCAGTGGGAGGCAAATGGGATGG
TATGTGAGCTAGGAGAAGGGCTGAACCCTCAGCCTTGACTATGTCTAGAGCCTCTTGGGG
AAGGGGCACCTCTCTTGAACCCCAAATGCTCTCTCTTCTTATTACCCAAACCCATGGCTC
TATTTCTTCTTCACATCCATTGTCTCTTCATGTCTATTCCATTCCCTTCGGCCAAACAGA
CAGGTGGAAAAACTGAGACAGGCAGTTTCAGAGATGGACAGAGAACTTTATTTTGGATTG
TGGATGTGGACTTTTTTGTACATAAATAAGAAAAACCAAAATACTCCAAAGATGACTTCC
CCTGCCTCCTACTCCAGTATGACAGAGGAGGATGTAAGGCCTTAGCCATGATCTGCAGGG
GTCTGGGAGTCAGGCCCGGCCTATTGCTTGGGTCTCTCTCTATTTATATATCTAAGTTCA
CAGTGTTTCTTATTCCCCCCTAAGCTTCTAGAGGCTCATGGCCCTGTAGTTAGGCCTGGC
TCATTCTGCACCTTTCCAGGGAGGTGGAAGGACCCTGTGCCCTCCTTCCCAATCTTCTTT
TTCAGGCTCGCCAAGGCCTAGGACCTATGTTGTAATTTTACTTTTTATTTCTAAAGTTGT
AGTGAAGCTCTCACCCATAATAAAGGTTGTGAATGTTCAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_006099.3 unedited
GGCGAGCCTGTAAGCCTCCCGCTGTTTTGACCTCCATAGAAGACACCGGGACCGATCCAG
CCTCCGGACTCTAGCCTAGGCCGCGGGACGGATAACAATTTCACACAGGAAACAGCTATG
ACCATTAGGCCTATTTAGGTGACACTATAGAACAAGTTTGTACAAAAAAGCAGGCTGGTA
CCGGTCCGGAATTCCCGGGATCTGGGCCTGAGCTCCGGCTCCGGCTGGGGCGCCTGCGAT
GTCTCAAGATGGCGGAGCTGGGCGAATTAAAGCACATGGTGATGAGTTTCCGGGTGTCTG
AGCTCCAGGTGCTTCTTGGCTTTGCTGGCCGGAACAAGAGTGGACGGAAGCACGAGCTCC
TGGCCAAGGCTCTGCACCTCCTGAAGTCCAGCTGTGCCCCTAGTGTCCAGATGAAGATCA
AAGAGCTTTACCGACGACGCTTTCCCCGGAAGACCCTGGGGCCCTCTGATCTCTCCCTTC
TCTCTTTGCCCCCTGGCACCTCTCCTGTAGGCTCCCCTGGTCCTCTAGCTCCCATTCCCC
CAACGCTGTTGGCCCCTGGCACCCTGCTGGGCCCCAAGCGTGAGGTGGACATGCACCCCC
CTCTGCCCCAGCCTGTGCACCCTGATGTCACCATGAAACCATTGCCCTTCTATGAAGTCT
ATGGGGAGCTCATCCGGCCCACCACCCTTGCATCCACTTCTAGCCAGCGGTTTGAGGAAG
CGCACTTTACCTTTGCCCTCACACCCCAGCAAGTGCAGCAGATTCTTACATCCAGAGAGG
TTCTGCCAGGAGCCAAATGTGATTATACCATACAGGTGCAGCTAAGTTCTGTCTCTTGTG
AGACCAGCTGCCCCCAGGAAGATTATTTTCCCCCAACCTCTTTGTCAAGTCAATGGAAAC
TGTGCCCTGCGGTTACTCCCCACAGATGGGCGAGCCCAGAGCCAGCGCCCATCAACATCC
AA
Restriction Sites Please inquire     
ACCN NM_006099
ORF Size 1887 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_006099.3, NP_006090.2
RefSeq Size 2902
RefSeq ORF 1887
Locus ID 10401
Domains SAP, zf-MIZ
Protein Families Transcription Factors
Protein Pathways Jak-STAT signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis
Gene Summary This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

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