Thimet Oligopeptidase (THOP1) (NM_003249) Human Untagged Clone

CAT#: SC324358

THOP1 (untagged)-Human thimet oligopeptidase 1 (THOP1)


  "NM_003249" in other vectors (5)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol THOP1
Synonyms EP24.15; MEPD_HUMAN; MP78; TOP
Vector pCMV6-AC
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>OriGene sequence for NM_003249.3 GCCCCGGGAGCGCGGGCGGCGGGCCCCTTGGTCCTCAGGCGGCCGTGGCGGCGGTGGCGG
CGGTTGGGCCGAGGCAGGCGGCCTCAGTGGCCGAGGTGGCTGGACGCGTAGCAGGTGGAA
GGAGGGAGGGAGCCGCAGGCGCAGACCCACCCGCCATGAAGCCCCCCGCAGCCTGTGCAG
GAGACATGGCGGACGCAGCATCTCCGTGCTCTGTGGTAAACGACCTGCGGTGGGACCTGA
GTGCCCAGCAGATAGAGGAGCGCACCAGGGAGCTCATCGAGCAGACCAAGCGCGTGTATG
ACCAGGTTGGCACCCAGGAGTTTGAGGACGTGTCCTACGAGAGCACGCTCAAGGCGCTGG
CCGATGTGGAGGTCACCTACACAGTTCAGAGGAATATCCTTGACTTCCCCCAGCATGTTT
CCCCCTCCAAGGACATCCGGACAGCCAGCACAGAGGCCGACAAGAAGCTCTCTGAGTTCG
ACGTGGAGATGAGCATGAGGGAGGACGTGTACCAGAGGATCGTGTGGCTCCAGGAGAAAG
TTCAGAAGGACTCACTGAGGCCCGAGGCTGCGCGGTACCTGGAGCGGCTAATCAAGCTGG
GCCGGAGAAATGGGCTTCACCTCCCCAGAGAGACTCAGGAAAACATCAAACGCATCAAGA
AGAAGCTGAGCCTTCTGTGCATCGACTTCAACAAGAACCTGAACGAGGACACGACCTTCC
TGCCCTTCACGCTCCAGGAGCTAGGAGGGCTCCCCGAGGACTTTCTGAACTCCCTGGAGA
AGATGGAGGACGGCAAGTTGAAGGTCACCCTCAAGTACCCCCATTACTTCCCCCTCCTGA
AGAAATGCCACGTGCCTGAGACCAGGAGGAAAGTGGAGGAGGCCTTCAACTGCCGGTGCA
AGGAGGAGAACTGCGCTATCCTCAAGGAGCTGGTGACGCTGCGGGCCCAGAAGTCCCGCC
TGCTGGGGTTCCACACGCACGCCGACTATGTCCTGGAGATGAACATGGCCAAGACCAGCC
AGACCGTGGCCACCTTCCTAGATGAGCTGGCGCAGAAGCTGAAGCCCCTGGGGGAGCAGG
AGCGTGCGGTGATTCTGGAGCTGAAGCGTGCGGAGTGCGAGCGCCGGGGCCTGCCCTTCG
ACGGCCGCATCCGTGCCTGGGACATGCGCTACTACATGAACCAGGTGGAGGAGACGCGCT
ACTGCGTGGACCAGAACCTGCTCAAGGAGTACTTCCCCGTGCAGGTGGTCACGCACGGGC
TGCTGGGCATCTACCAGGAGCTCCTGGGGCTGGCCTTCCACCACGAGGAGGGCGCCAGTG
CCTGGCATGAGGACGTGCGGCTCTACACCGCGAGGGACGCGGCCTCGGGGGAGGTGGTCG
GCAAGTTCTACCTGGACCTGTACCCGCGGGAAGGAAAGTACGGGCACGCGGCCTGCTTTG
GCCTGCAGCCCGGCTGCCTGCGGCAGGATGGGAGCCGCCAGATCGCCATCGCGGCCATGG
TGGCCAACTTCACCAAGCCCACAGCCGACGCGCCCTCGCTGCTGCAGCATGACGAGGTGG
AGACCTACTTCCATGAGTTTGGCCACGTGATGCACCAGCTCTGCTCCCAGGCGGAGTTCG
CCATGTTCAGCGGGACCCACGTGGAGCGGGACTTTGTGGAGGCGCCGTCGCAGATGCTGG
AGAACTGGGTGTGGGAGCAGGAGCCGCTGCTGCGGATGTCGCGGCACTACCGCACAGGCA
GCGCCGTGCCCCGGGAGCTCCTGGAGAAGCTCATTGAGTCCCGGCAGGCCAACACAGGCC
TCTTCAACCTGCGCCAGATCGTCCTCGCCAAGGTGGACCAGGCCCTGCACACGCAGACGG
ACGCAGACCCCGCCGAGGAGTATGCGCGGCTCTGCCAGGAGATCCTCGGGGTCCCGGCCA
CGCCAGGAACCAACATGCCTGCAACCTTCGGCCATCTGGCAGGTGGCTACGACGCCCAGT
ACTACGGGTACCTGTGGAGCGAGGTGTATTCCATGGACATGTTCCACACGCGCTTCAAGC
AGGAGGGTGTCCTGAACAGCAAGGTTGGCATGGATTACAGAAGCTGCATCCTGAGACCCG
GCGGTTCCGAGGATGCCAGCGCCATGCTGAGGCGCTTCCTGGGCCGTGACCCCAAGCAGG
ACGCCTTCCTCCTGAGCAAGGGGCTGCAGGTCGGGGGCTGCGAGCCCGAGCCGCAGGTCT
GCTGAGGCCTGGCACTGCGACTGCCCAGTCTGGCCTGCGCTCCCGCCGCCCTGGTGCCTT
AGCCCCCGGCACAGGATGGGGCAGGCTCTGGCACAGTGCCTGGGACTGGCAGGGTGGCTG
AGCGGCTGTCTTGCCTCTTGTCATTGTCTGTCCCCACCCGGTCGTGGCCCACCCGGCTAG
AGACGGCGTCCTCAAGGCATCTGGAGGGCTTTCGTGGCTGCCAGGGCCTGGTCTTTGTTG
CACTAACACGTCTCCTCTCTGGGAAACGTCCCTTGTCAGGAGACGGCTCTTCTTTGAAAT
GAGGTCATTAAAAGGAAACAGAAAAAGAGAAAAAAAAAAAAAAAAAAA
>OriGene 5' read for NM_003249.3 unedited
GGCCATTTGTATACGACTCCTATAGGGCGGCCGGGAAACGGCACGAGGGCCCCGGGAGCG
CGGGCGGCGGGCCCCTTGGTCCTCAGGCGGCCGTGGCGGCGGTGGCGGCGGTTGGGCCGA
GGCAGGCGGCCTCAGTGGCCGAGGTGGCTGGACGCGTAGCAGGTGGAAGGAGGGAGGGAG
CCGCAGGCGCAGACCCACCCGCCATGAAGCCCCCCGCAGCCTGTGCAGGAGACATGGCGG
ACGCAGCATCTCCGTGCTCTGTGGTAAACGACCTGCGGTGGGACCTGAGTGCCCAGCAGA
TAGAGGAGCGCACCAGGGAGCTCATCGAGCAGACCAAGCGCGTGTATGACCAGGTTGGCA
CCCAGGAGTTTGAGGACGTGTCCTACGAGAGCACGCTCAAGGCGCTGGCCGATGTGGAGG
TCACCTACACAGTTCAGAGGAATATCCTTGACTTCCCCCAGCATGTTTCCCCCTCCAAGG
ACATCCGGACAGCCAGCACAGAGGCCGACAAGAAGCTCTCTGAGTTCGACGTGGAGATGA
GCATGAGGGAGGACGTGTACCAGAGGATCGTGTGGCTCCAGGAGAAAGTTCCAAAGGACT
CACTTGAGGCCCCGAGGCTGCGCGGTACCTGGAAGCGGCTAATCAAGCTTGGGCCGGAGA
AATGGGGCTTCACCCTCCCCCGAGAGACTCAGGAAAAACCTCAACCGCACCAAGAAAAAG
CCTGACCCTTCTGTGCCTTTGACTTTAACGC
Restriction Sites Please inquire     
ACCN NM_003249
ORF Size 2070 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
Reference Data
RefSeq NM_003249.3, NP_003240.1
RefSeq Size 2568
RefSeq ORF 2070
Locus ID 7064
Domains Peptidase_M3
Protein Families Druggable Genome, Protease
Protein Pathways Renin-angiotensin system
Gene Summary The protein encoded by this gene is a kininase that uses zinc as a cofactor. The encoded oligopeptidase cleaves cytosolic peptides, making them unavailable for display on antigen-presenting cells. This protein also cleaves neuropeptides under 20 aa in length and can degrade beta-amyloid precursor protein to amyloidogenic peptides. [provided by RefSeq, Nov 2015]

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